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Karyopharm Therapeutics
KPTI

Overview Fund Activity

149 hedge funds and large institutions have $303M invested in Karyopharm Therapeutics in 2022 Q2 according to their latest regulatory filings, with 28 funds opening new positions, 39 increasing their positions, 58 reducing their positions, and 13 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
149
Holders Change
+10
Holders Change %
+7.19%
% of All Funds
2.52%
Holding in Top 10
–
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-100%
% of All Funds
–
New
28
Increased
39
Reduced
58
Closed
13
Calls
$4.7M
Puts
$1.92M
Net Calls
+$2.77M
Net Calls Change
-$5.1M

Top Buyers

1
Walleye Capital
Walleye Capital
New York
$7.87M
2
Jacobs Levy Equity Management
Jacobs Levy Equity Management
New Jersey
$6.89M
3
RCMNY
Rubric Capital Management (New York)
New York
$19.8M
4
ECM
ExodusPoint Capital Management
New York
$2.91M
5
BNP Paribas Financial Markets
BNP Paribas Financial Markets
France
$2.64M

Top Sellers

1
CC
Commodore Capital
New York
$8.73M
2
ITP
Iron Triangle Partners
Connecticut
$4.96M
3
Millennium Management
Millennium Management
New York
$2.73M
4
FCM
Frontier Capital Management
Massachusetts
$2.85M
5
Bank of America
Bank of America
North Carolina
$2.16M
Name Holding Trade Value Shares
Change 		Shares
Change %
State Street
1
State Street
Massachusetts
$46.7M -$2.73M -40,312 -6%
BlackRock
2
BlackRock
New York
$36.6M +$880K +13,015 +2%
PAI
3
Palo Alto Investors
California
$25.4M – – –
RCMNY
4
Rubric Capital Management (New York)
New York
$19.8M +$3.57M +52,837 +22%
Vanguard Group
5
Vanguard Group
Pennsylvania
$19M +$1.18M +17,418 +7%
Morgan Stanley
6
Morgan Stanley
New York
$10.8M -$1.92M -28,391 -15%
CC
7
Commodore Capital
New York
$8.73M -$7.33M -108,362 -46%
Nuveen Asset Management
8
Nuveen Asset Management
Illinois
$8.55M +$344K +5,089 +4%
Walleye Capital
9
Walleye Capital
New York
$7.87M +$7.5M +110,822 +2,001%
Jacobs Levy Equity Management
10
Jacobs Levy Equity Management
New Jersey
$6.89M +$3.89M +57,569 +130%
CWG
11
C WorldWide Group
Denmark
$6.77M – – –
Goldman Sachs
12
Goldman Sachs
New York
$6.52M +$2.47M +36,500 +61%
Geode Capital Management
13
Geode Capital Management
Massachusetts
$5.98M -$52.2K -772 -0.9%
RHJA
14
Rice Hall James & Associates
California
$5.93M -$131K -1,940 -2%
CS
15
Candriam SCA
Luxembourg
$5.57M -$448K -6,620 -7%
ITP
16
Iron Triangle Partners
Connecticut
$4.96M -$4.06M -60,000 -45%
Two Sigma Investments
17
Two Sigma Investments
New York
$4.62M -$425K -6,278 -8%
Two Sigma Advisers
18
Two Sigma Advisers
New York
$4.45M +$950K +14,046 +27%
Northern Trust
19
Northern Trust
Illinois
$3.46M +$17K +251 +0.5%
ACM
20
Altium Capital Management
New York
$3.16M +$248K +3,667 +9%
ECM
21
ExodusPoint Capital Management
New York
$2.91M +$2.83M +41,767 +3,215%
FCM
22
Frontier Capital Management
Massachusetts
$2.85M -$2.92M -43,119 -51%
Millennium Management
23
Millennium Management
New York
$2.73M -$2.92M -43,166 -52%
Deutsche Bank
24
Deutsche Bank
Germany
$2.68M -$22.3K -329 -0.8%
BNP Paribas Financial Markets
25
BNP Paribas Financial Markets
France
$2.64M +$2.6M +38,383 +6,734%
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