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Karyopharm Therapeutics
KPTI

Overview Fund Activity

85 hedge funds and large institutions have $636M invested in Karyopharm Therapeutics in 2015 Q1 according to their latest regulatory filings, with 15 funds opening new positions, 49 increasing their positions, 14 reducing their positions, and 11 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
85
Holders Change
+4
Holders Change %
+4.94%
% of All Funds
2.27%
Holding in Top 10
1
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-50%
% of All Funds
0.03%
New
15
Increased
49
Reduced
14
Closed
11
Calls
$2.76M
Puts
$4.52M
Net Calls
-$1.76M
Net Calls Change
-$1.45M

Top Buyers

1
PAI
Palo Alto Investors
California
$29.1M
2
TCM
Tekla Capital Management
Massachusetts
$14.6M
3
State Street
State Street
Massachusetts
$30.2M
4
Fidelity Investments
Fidelity Investments
Massachusetts
$159M
5
PHS
PFM Health Sciences
California
$34.4M

Top Sellers

1
FCMI
Foresite Capital Management I
California
$0
2
BA
BlackRock Advisors
Delaware
$8.53M
3
BG
BlackRock Group
United Kingdom
$0
4
DCM
Driehaus Capital Management
Illinois
$0
5
UBS Group
UBS Group
Switzerland
$2.7M
Name Holding Trade Value Shares
Change 		Shares
Change %
Fidelity Investments
1
Fidelity Investments
Massachusetts
$159M +$8.4M +18,288 +6%
Franklin Resources
2
Franklin Resources
California
$148M +$6.01M +13,099 +4%
PHS
3
PFM Health Sciences
California
$34.4M +$8.38M +18,248 +32%
State Street
4
State Street
Massachusetts
$30.2M +$9.6M +20,908 +47%
PAI
5
Palo Alto Investors
California
$29.1M +$29.1M +63,402 New
BFA
6
BlackRock Fund Advisors
California
$26.6M +$3.19M +6,944 +14%
SAM
7
Sectoral Asset Management
Quebec, Canada
$21.6M +$5.43M +11,823 +33%
Vanguard Group
8
Vanguard Group
Pennsylvania
$17.2M +$4.48M +9,757 +35%
TCM
9
Tekla Capital Management
Massachusetts
$14.6M +$10.4M +22,614 +246%
BIT
10
BlackRock Institutional Trust
California
$13M +$6.31M +13,735 +94%
AllianceBernstein
11
AllianceBernstein
Tennessee
$12.5M -$289K -629 -2%
CAM
12
Cormorant Asset Management
Massachusetts
$9.21M -$2.57M -5,601 -22%
BA
13
BlackRock Advisors
Delaware
$8.53M -$10.1M -21,903 -54%
CS
14
Candriam SCA
Luxembourg
$8.24M -$888K -1,934 -10%
BBA
15
Baker Bros. Advisors
New York
$6.64M +$3.76M +8,193 +131%
CGI
16
CI Global Investments
California
$6.12M +$6.12M +13,333 New
Wellington Management Group
17
Wellington Management Group
Massachusetts
$5.38M -$1.24M -2,690 -19%
Northern Trust
18
Northern Trust
Illinois
$5.24M +$688K +1,499 +15%
Allianz Asset Management
19
Allianz Asset Management
Germany
$4.83M +$4.83M +10,512 New
PC
20
PointState Capital
New York
$4.59M +$1.53M +3,333 +50%
Bank of America
21
Bank of America
North Carolina
$4.56M +$3.37M +7,335 +284%
TG
22
TCW Group
California
$4.25M -$893K -1,944 -17%
GC
23
Guggenheim Capital
Illinois
$4M -$1.79M -3,900 -31%
NLVP
24
New Leaf Venture Partners
New York
$3.88M – – –
Geode Capital Management
25
Geode Capital Management
Massachusetts
$3.77M +$1.4M +3,054 +59%
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