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Karyopharm Therapeutics

103 hedge funds and large institutions have $306M invested in Karyopharm Therapeutics in 2019 Q2 according to their latest regulatory filings, with 17 funds opening new positions, 39 increasing their positions, 30 reducing their positions, and 18 closing their positions.

New
Increased
Maintained
Reduced
Closed

463% more call options, than puts

Call options by funds: $4.58M | Put options by funds: $815K

30% more repeat investments, than reductions

Existing positions increased: 39 | Existing positions reduced: 30

2% more capital invested

Capital invested by funds: $300M → $306M (+$6.39M)

0.01% less ownership

Funds ownership: 5.61%5.6% (-0.01%)

6% less first-time investments, than exits

New positions opened: 17 | Existing positions closed: 18

5% less funds holding

Funds holding: 108103 (-5)

Holders
103
Holders Change
-5
Holders Change %
-4.63%
% of All Funds
2.24%
Holding in Top 10
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
New
17
Increased
39
Reduced
30
Closed
18
Calls
$4.58M
Puts
$815K
Net Calls
+$3.77M
Net Calls Change
+$990K
Name Holding Trade Value Shares
Change
Change in
Stake
Wellington Management Group
1
Wellington Management Group
Massachusetts
$50.5M +$5.62K +70 +0%
CCM
2
Consonance Capital Management
New York
$34.8M +$3.45M +42,956 +12%
PAI
3
Palo Alto Investors
California
$31.5M
BlackRock
4
BlackRock
New York
$27.1M +$1.86M +23,180 +8%
O
5
OrbiMed
New York
$18.9M +$16.9M +209,898 New
Vanguard Group
6
Vanguard Group
Pennsylvania
$17.9M +$1.98M +24,639 +14%
Point72 Asset Management
7
Point72 Asset Management
Connecticut
$15.6M +$13.9M +173,088 New
CS
8
Candriam SCA
Luxembourg
$11.6M +$428K +5,333 +4%
EA
9
Emerald Advisers
Pennsylvania
$8.84M -$171K -2,124 -2%
EMFAT
10
Emerald Mutual Fund Advisers Trust
Pennsylvania
$8.24M -$5.78K -72 -0.1%
State Street
11
State Street
Massachusetts
$6.71M +$835K +10,403 +16%
Dimensional Fund Advisors
12
Dimensional Fund Advisors
Texas
$6.62M -$134K -1,674 -2%
Fidelity Investments
13
Fidelity Investments
Massachusetts
$6.28M -$2.6M -32,380 -32%
Citadel Advisors
14
Citadel Advisors
Florida
$5.28M -$4.88M -60,765 -51%
D.E. Shaw & Co
15
D.E. Shaw & Co
New York
$4.82M +$1.92M +23,939 +80%
Geode Capital Management
16
Geode Capital Management
Massachusetts
$4.62M +$990K +12,336 +32%
FCM
17
Frontier Capital Management
Massachusetts
$4.09M -$2.73K -34 -0.1%
Northern Trust
18
Northern Trust
Illinois
$3.68M +$64.3K +801 +2%
PCA
19
Private Capital Advisors
Connecticut
$3.16M +$439K +5,467 +18%
FMBTD
20
First Midwest Bank Trust Division
Illinois
$2.64M -$909K -11,323 -28%
AI
21
Atom Investors
Texas
$2.52M +$2.25M +28,025 New
N
22
Nuveen
North Carolina
$2.31M +$2.06M +25,714 New
Macquarie Group
23
Macquarie Group
Australia
$2.28M
BI
24
BVF Inc
California
$2.13M +$1.9M +23,684 New
Charles Schwab
25
Charles Schwab
California
$1.82M +$269K +3,349 +20%

KPTI Hedge Fund Activity: Q2 2019 in Review

103 of the 4,605 institutional investors tracked by Wall St. Rank reported a position in Karyopharm Therapeutics (KPTI) for Q2 2019, worth a combined $306M — up 2.1% from $300M a quarter earlier.

Sellers outnumbered buyers: 18 funds closed out of KPTI and 17 opened new positions — a net loss of 1 holder — while 30 trimmed existing stakes and 39 added.

The largest buyer was OrbiMed, opening a new position worth an estimated $16.9M. The largest seller was Millennium Management, cutting an estimated $14.2M.

  • 103 institutional investors held Karyopharm Therapeutics (KPTI) as of Q2 2019, down from 108 in Q1 2019.
  • Funds reported $306M of Karyopharm Therapeutics stock for Q2 2019, up 2.1% quarter-over-quarter.
  • 17 funds opened new Karyopharm Therapeutics positions in Q2 2019 and 18 closed out, a net change of -1 holder.
  • The largest Karyopharm Therapeutics buyer in Q2 2019 was OrbiMed, an estimated $16.9M added.
  • The largest Karyopharm Therapeutics seller in Q2 2019 was Millennium Management, an estimated $14.2M sold.

Based on aggregated 13F filings for Q2 2019.