KPTI icon

Karyopharm Therapeutics
KPTI

Overview Fund Activity

154 hedge funds and large institutions have $334M invested in Karyopharm Therapeutics in 2022 Q4 according to their latest regulatory filings, with 32 funds opening new positions, 63 increasing their positions, 39 reducing their positions, and 24 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
154
Holders Change
+7
Holders Change %
+4.76%
% of All Funds
2.48%
Holding in Top 10
–
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-100%
% of All Funds
–
New
32
Increased
63
Reduced
39
Closed
24
Calls
$1.83M
Puts
$1.12M
Net Calls
+$703K
Net Calls Change
-$761K

Top Buyers

1
APM
Avidity Partners Management
Texas
$32.8M
2
RCMNY
Rubric Capital Management (New York)
New York
$28.2M
3
AC
Armistice Capital
New York
$13.1M
4
Marshall Wace
Marshall Wace
United Kingdom
$7.51M
5
Point72 Asset Management
Point72 Asset Management
Connecticut
$6.77M

Top Sellers

1
RHJA
Rice Hall James & Associates
California
$0
2
ACM
Altium Capital Management
New York
$0
3
FCM
Frontier Capital Management
Massachusetts
$0
4
LOAMS
Lombard Odier Asset Management (Switzerland)
Switzerland
$0
5
State Street
State Street
Massachusetts
$28.2M
Name Holding Trade Value Shares
Change 		Shares
Change %
APM
1
Avidity Partners Management
Texas
$32.8M +$32.8M +642,261 New
BlackRock
2
BlackRock
New York
$28.9M +$2.02M +39,686 +8%
RCMNY
3
Rubric Capital Management (New York)
New York
$28.2M +$14.6M +286,967 +108%
State Street
4
State Street
Massachusetts
$28.2M -$2.46M -48,220 -8%
PAI
5
Palo Alto Investors
California
$19.2M +$116K +2,276 +0.6%
Vanguard Group
6
Vanguard Group
Pennsylvania
$17.7M +$1.31M +25,607 +8%
AC
7
Armistice Capital
New York
$13.1M +$13.1M +256,904 New
Citadel Advisors
8
Citadel Advisors
Florida
$12.3M +$6.3M +126,901 +105%
Jacobs Levy Equity Management
9
Jacobs Levy Equity Management
New Jersey
$7.65M +$2.27M +44,458 +42%
Marshall Wace
10
Marshall Wace
United Kingdom
$7.51M +$6.97M +136,739 +1,289%
Point72 Asset Management
11
Point72 Asset Management
Connecticut
$6.77M +$6.76M +132,541 +56,885%
CC
12
Commodore Capital
New York
$6.58M – – –
ITP
13
Iron Triangle Partners
Connecticut
$6.55M +$6.55M +128,452 New
Nuveen Asset Management
14
Nuveen Asset Management
Illinois
$5.42M -$1.28M -25,156 -19%
CS
15
Candriam SCA
Luxembourg
$5.22M +$680K +13,333 +15%
Bank of America
16
Bank of America
North Carolina
$5.14M +$2.65M +51,953 +106%
CWG
17
C WorldWide Group
Denmark
$5.1M – – –
JPMorgan Chase & Co
18
JPMorgan Chase & Co
New York
$5.04M +$4.43M +86,863 +727%
Geode Capital Management
19
Geode Capital Management
Massachusetts
$4.68M +$159K +3,113 +4%
WP
20
Woodline Partners
California
$4.5M -$640K -12,558 -12%
Morgan Stanley
21
Morgan Stanley
New York
$4.38M +$712K +13,970 +19%
OM
22
Opaleye Management
Massachusetts
$4.28M +$4.28M +80,456 New
CH
23
CVI Holdings
Delaware
$4.26M +$4.26M +83,494 New
ECM
24
ExodusPoint Capital Management
New York
$3.76M +$1.36M +26,590 +56%
Goldman Sachs
25
Goldman Sachs
New York
$3.59M -$1.02M -19,903 -22%
1
2 3 4 5