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Karyopharm Therapeutics

60 hedge funds and large institutions have $311M invested in Karyopharm Therapeutics in 2014 Q1 according to their latest regulatory filings, with 15 funds opening new positions, 18 increasing their positions, 24 reducing their positions, and 9 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
60
Holders Change
+6
Holders Change %
+11.11%
% of All Funds
1.73%
Holding in Top 10
1
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
0.03%
New
15
Increased
18
Reduced
24
Closed
9
Calls
Puts
Net Calls
Net Calls Change
Name Holding Trade Value Shares
Change
Shares
Change %
Fidelity Investments
1
Fidelity Investments
Massachusetts
$72.5M
Franklin Resources
2
Franklin Resources
California
$62M +$37.7M +81,414 +155%
FCMI
3
Foresite Capital Management I
California
$49M
BA
4
BlackRock Advisors
Delaware
$19.7M +$9.6M +20,721 +95%
AllianceBernstein
5
AllianceBernstein
Tennessee
$13.8M -$247K -534 -2%
Wellington Management Group
6
Wellington Management Group
Massachusetts
$11.8M -$3.78M -8,162 -24%
PHS
7
PFM Health Sciences
California
$9.56M -$17.9M -38,662 -65%
CAM
8
Cormorant Asset Management
Massachusetts
$8.65M +$5.56M +12,000 +180%
BFA
9
BlackRock Fund Advisors
California
$6.83M +$242K +523 +4%
Vanguard Group
10
Vanguard Group
Pennsylvania
$4.44M +$2.02M +4,351 +83%
BG
11
BlackRock Group
United Kingdom
$4.2M +$1.63M +3,508 +63%
TG
12
TCW Group
California
$3.88M -$3.57M -7,715 -48%
State Street
13
State Street
Massachusetts
$3.36M -$18.5K -40 -0.5%
Northern Trust
14
Northern Trust
Illinois
$2.96M -$309K -666 -9%
BIT
15
BlackRock Institutional Trust
California
$2.5M -$1.32M -2,846 -35%
BlackRock
16
BlackRock
New York
$2.45M +$2.37M +5,117 +2,958%
GC
17
Guggenheim Capital
Illinois
$2.27M +$2.27M +4,889 New
JPMorgan Chase & Co
18
JPMorgan Chase & Co
New York
$2.21M -$1.15M -2,476 -34%
DCM
19
Driehaus Capital Management
Illinois
$2.11M -$673K -1,452 -24%
EAM
20
Eventide Asset Management
Massachusetts
$2.09M +$1.18M +2,547 +129%
Principal Financial Group
21
Principal Financial Group
Iowa
$1.98M -$1.45M -3,133 -42%
EI
22
EAM Investors
California
$1.97M +$1.97M +4,253 New
BBA
23
Baker Bros. Advisors
New York
$1.83M -$69K -149 -4%
Bank of New York Mellon
24
Bank of New York Mellon
New York
$1.69M +$861K +1,858 +103%
PC
25
PointState Capital
New York
$1.55M +$1.55M +3,333 New