KPTI icon

Karyopharm Therapeutics
KPTI

Overview Fund Activity

87 hedge funds and large institutions have $41.2M invested in Karyopharm Therapeutics in 2024 Q4 according to their latest regulatory filings, with 14 funds opening new positions, 21 increasing their positions, 23 reducing their positions, and 18 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
87
Holders Change
-4
Holders Change %
-4.4%
% of All Funds
1.16%
Holding in Top 10
–
Holding in Top 10 Change
–
Holding in Top 10 Change %
–
% of All Funds
–
New
14
Increased
21
Reduced
23
Closed
18
Calls
$196K
Puts
$47K
Net Calls
+$149K
Net Calls Change
-$712K

Top Buyers

1
Morgan Stanley
Morgan Stanley
New York
$2.38M
2
Adage Capital Partners
Adage Capital Partners
Massachusetts
$4.27M
3
Jane Street
Jane Street
New York
$506K
4
Susquehanna International Group
Susquehanna International Group
Pennsylvania
$449K
5
Marshall Wace
Marshall Wace
United Kingdom
$1.63M

Top Sellers

1
EP
Eversept Partners
New York
$1.41M
2
AA
AlphaCentric Advisors
Puerto Rico
$0
3
JPMorgan Chase & Co
JPMorgan Chase & Co
New York
$187K
4
D.E. Shaw & Co
D.E. Shaw & Co
New York
$155K
5
BNP Paribas Financial Markets
BNP Paribas Financial Markets
France
$889K
Name Holding Trade Value Shares
Change 		Shares
Change %
Vanguard Group
1
Vanguard Group
Pennsylvania
$5.17M – – –
Adage Capital Partners
2
Adage Capital Partners
Massachusetts
$4.27M +$1.35M +133,334 +46%
PAI
3
Palo Alto Investors
California
$3.32M -$132K -13,013 -4%
BlackRock
4
BlackRock
New York
$2.55M +$88.2K +8,699 +4%
Morgan Stanley
5
Morgan Stanley
New York
$2.38M +$2.29M +225,970 +2,741%
Citadel Advisors
6
Citadel Advisors
Florida
$2.1M – – –
Marshall Wace
7
Marshall Wace
United Kingdom
$1.63M +$217K +21,279 +15%
CCM
8
Catalio Capital Management
New York
$1.58M +$1.58M +155,625 New
EP
9
Eversept Partners
New York
$1.41M -$2.34M -230,609 -62%
APM
10
Avidity Partners Management
Texas
$1.37M – – –
GCP
11
GSA Capital Partners
United Kingdom
$1.08M -$120K -11,818 -10%
CWG
12
C WorldWide Group
Denmark
$1.01M – – –
UOC
13
UBS O'Connor
Illinois
$1M +$194K +19,170 +24%
Geode Capital Management
14
Geode Capital Management
Massachusetts
$942K +$25K +2,462 +3%
Goldman Sachs
15
Goldman Sachs
New York
$903K -$639 -63 -0.1%
BNP Paribas Financial Markets
16
BNP Paribas Financial Markets
France
$889K -$452K -44,564 -34%
Deutsche Bank
17
Deutsche Bank
Germany
$863K – – –
Renaissance Technologies
18
Renaissance Technologies
New York
$813K -$26.2K -2,587 -3%
KCM
19
Kennedy Capital Management
Missouri
$808K -$5.89K -581 -0.7%
Millennium Management
20
Millennium Management
New York
$781K -$68.2K -6,723 -8%
Jane Street
21
Jane Street
New York
$506K +$368K +36,237 +265%
ACM
22
Altium Capital Management
New York
$500K – – –
Susquehanna International Group
23
Susquehanna International Group
Pennsylvania
$449K +$245K +24,106 +120%
SCM
24
Silverarc Capital Management
Massachusetts
$403K +$25.4K +2,502 +7%
Macquarie Group
25
Macquarie Group
Australia
$338K – – –
1
2 3 4 5