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Karyopharm Therapeutics
KPTI

Overview Fund Activity

89 hedge funds and large institutions have $610M invested in Karyopharm Therapeutics in 2015 Q2 according to their latest regulatory filings, with 16 funds opening new positions, 41 increasing their positions, 18 reducing their positions, and 12 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
89
Holders Change
+4
Holders Change %
+4.71%
% of All Funds
2.4%
Holding in Top 10
1
Holding in Top 10 Change
–
Holding in Top 10 Change %
–
% of All Funds
0.03%
New
16
Increased
41
Reduced
18
Closed
12
Calls
$2.86M
Puts
$4.16M
Net Calls
-$1.3M
Net Calls Change
+$460K

Top Buyers

1
PAI
Palo Alto Investors
California
$47.1M
2
Citadel Advisors
Citadel Advisors
Florida
$12.3M
3
Millennium Management
Millennium Management
New York
$9.92M
4
State Street
State Street
Massachusetts
$33.6M
5
BFA
BlackRock Fund Advisors
California
$29M

Top Sellers

1
PHS
PFM Health Sciences
California
$22.4M
2
CGI
CI Global Investments
California
$0
3
PC
PointState Capital
New York
$0
4
Franklin Resources
Franklin Resources
California
$128M
5
CS
Candriam SCA
Luxembourg
$3.62M
Name Holding Trade Value Shares
Change 		Shares
Change %
Fidelity Investments
1
Fidelity Investments
Massachusetts
$146M +$4.76M +11,654 +3%
Franklin Resources
2
Franklin Resources
California
$128M -$3.84M -9,411 -3%
PAI
3
Palo Alto Investors
California
$47.1M +$21.2M +52,033 +82%
State Street
4
State Street
Massachusetts
$33.6M +$6.72M +16,464 +25%
BFA
5
BlackRock Fund Advisors
California
$29M +$5.31M +13,005 +22%
PHS
6
PFM Health Sciences
California
$22.4M -$8.23M -20,164 -27%
SAM
7
Sectoral Asset Management
Quebec, Canada
$19.4M +$155K +380 +0.8%
Vanguard Group
8
Vanguard Group
Pennsylvania
$19.1M +$3.77M +9,244 +25%
AllianceBernstein
9
AllianceBernstein
Tennessee
$15.9M +$4.74M +11,622 +43%
TCM
10
Tekla Capital Management
Massachusetts
$13M – – –
BIT
11
BlackRock Institutional Trust
California
$12.6M +$1.05M +2,568 +9%
Citadel Advisors
12
Citadel Advisors
Florida
$12.3M +$11.6M +28,519 +1,680%
Millennium Management
13
Millennium Management
New York
$9.92M +$7.3M +17,889 +279%
CAM
14
Cormorant Asset Management
Massachusetts
$8.19M – – –
BA
15
BlackRock Advisors
Delaware
$7.71M +$127K +310 +2%
BBA
16
Baker Bros. Advisors
New York
$5.9M – – –
Northern Trust
17
Northern Trust
Illinois
$4.73M +$77.9K +191 +2%
Wellington Management Group
18
Wellington Management Group
Massachusetts
$4.34M -$449K -1,099 -9%
AC
19
Ascend Capital
California
$4.08M +$4.08M +9,984 New
GC
20
Guggenheim Capital
Illinois
$3.78M +$216K +530 +6%
CS
21
Candriam SCA
Luxembourg
$3.62M -$3.7M -9,066 -51%
Geode Capital Management
22
Geode Capital Management
Massachusetts
$3.59M +$242K +594 +7%
NLVP
23
New Leaf Venture Partners
New York
$3.45M – – –
Bank of America
24
Bank of America
North Carolina
$3.41M -$638K -1,562 -16%
Bank of New York Mellon
25
Bank of New York Mellon
New York
$3.08M +$875K +2,144 +40%
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