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Karyopharm Therapeutics

89 hedge funds and large institutions have $610M invested in Karyopharm Therapeutics in 2015 Q2 according to their latest regulatory filings, with 16 funds opening new positions, 41 increasing their positions, 18 reducing their positions, and 12 closing their positions.

New
Increased
Maintained
Reduced
Closed

128% more repeat investments, than reductions

Existing positions increased: 41 | Existing positions reduced: 18

33% more first-time investments, than exits

New positions opened: 16 | Existing positions closed: 12

5% more funds holding

Funds holding: 8589 (+4)

0% more funds holding in top 10

Funds holding in top 10: 11 (0)

4% less capital invested

Capital invested by funds: $636M → $610M (-$25.8M)

31% less call options, than puts

Call options by funds: $2.86M | Put options by funds: $4.16M

Holders
89
Holders Change
+4
Holders Change %
+4.71%
% of All Funds
2.4%
Holding in Top 10
1
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
0.03%
New
16
Increased
41
Reduced
18
Closed
12
Calls
$2.86M
Puts
$4.16M
Net Calls
-$1.3M
Net Calls Change
+$460K
Name Holding Trade Value Shares
Change
Change in
Stake
Fidelity Investments
1
Fidelity Investments
Massachusetts
$146M +$5.04M +11,654 +3%
Franklin Resources
2
Franklin Resources
California
$128M -$4.07M -9,411 -3%
PAI
3
Palo Alto Investors
California
$47.1M +$22.5M +52,033 +82%
State Street
4
State Street
Massachusetts
$33.6M +$7.12M +16,464 +25%
BFA
5
BlackRock Fund Advisors
California
$29M +$5.62M +13,005 +22%
PHS
6
PFM Health Sciences
California
$22.4M -$8.72M -20,164 -27%
SAM
7
Sectoral Asset Management
Quebec, Canada
$19.4M +$164K +380 +0.8%
Vanguard Group
8
Vanguard Group
Pennsylvania
$19.1M +$4M +9,244 +25%
AllianceBernstein
9
AllianceBernstein
Tennessee
$15.9M +$5.02M +11,622 +43%
TCM
10
Tekla Capital Management
Massachusetts
$13M
BIT
11
BlackRock Institutional Trust
California
$12.6M +$1.11M +2,568 +9%
Citadel Advisors
12
Citadel Advisors
Florida
$12.3M +$12.3M +28,519 +1,680%
Millennium Management
13
Millennium Management
New York
$9.92M +$7.73M +17,889 +279%
CAM
14
Cormorant Asset Management
Massachusetts
$8.19M
BA
15
BlackRock Advisors
Delaware
$7.71M +$134K +310 +2%
BBA
16
Baker Bros. Advisors
New York
$5.9M
Northern Trust
17
Northern Trust
Illinois
$4.73M +$82.6K +191 +2%
Wellington Management Group
18
Wellington Management Group
Massachusetts
$4.34M -$475K -1,099 -9%
AC
19
Ascend Capital
California
$4.08M +$4.32M +9,984 New
GC
20
Guggenheim Capital
Illinois
$3.77M +$229K +530 +6%
CS
21
Candriam SCA
Luxembourg
$3.62M -$3.92M -9,066 -51%
Geode Capital Management
22
Geode Capital Management
Massachusetts
$3.59M +$257K +594 +7%
NLVP
23
New Leaf Venture Partners
New York
$3.45M
Bank of America
24
Bank of America
North Carolina
$3.41M -$675K -1,562 -16%
Bank of New York Mellon
25
Bank of New York Mellon
New York
$3.08M +$927K +2,144 +40%

KPTI Hedge Fund Activity: Q2 2015 in Review

89 of the 3,712 institutional investors tracked by Wall St. Rank reported a position in Karyopharm Therapeutics (KPTI) for Q2 2015, worth a combined $610M — down 4.1% from $636M a quarter earlier.

Buyers outnumbered sellers: 16 funds opened new KPTI positions and 12 closed out — a net gain of 4 holders — while 41 added to existing stakes and 18 trimmed.

The largest buyer was Palo Alto Investors, adding an estimated $22.5M. The largest seller was PFM Health Sciences, cutting an estimated $8.72M.

  • 89 institutional investors held Karyopharm Therapeutics (KPTI) as of Q2 2015, up from 85 in Q1 2015.
  • Funds reported $610M of Karyopharm Therapeutics stock for Q2 2015, down 4.1% quarter-over-quarter.
  • 16 funds opened new Karyopharm Therapeutics positions in Q2 2015 and 12 closed out, a net change of +4 holders.
  • The largest Karyopharm Therapeutics buyer in Q2 2015 was Palo Alto Investors, an estimated $22.5M added.
  • The largest Karyopharm Therapeutics seller in Q2 2015 was PFM Health Sciences, an estimated $8.72M sold.

Based on aggregated 13F filings for Q2 2015.