Karyopharm TherapeuticsKPTI
KPTI
0
Funds holding %
of 7,390 funds
0
Analysts bullish %
of 3 analysts
Fund manager confidence
Based on 2024 Q4 regulatory filings by fund managers ($100M+ AUM)
317% more call options, than puts
Call options by funds: $196K | Put options by funds: $47K
0.49% less ownership
Funds ownership: 48.76% [Q3] → 48.27% (-0.49%) [Q4]
9% less repeat investments, than reductions
Existing positions increased: 21 | Existing positions reduced: 23
4% less funds holding
Funds holding: 90 [Q3] → 86 (-4) [Q4]
18% less capital invested
Capital invested by funds: $50.4M [Q3] → $41.2M (-$9.17M) [Q4]
22% less first-time investments, than exits
New positions opened: 14 | Existing positions closed: 18
Research analyst outlook
3 Wall Street Analysts provided 1 year price targets over the past 3 months
Low target
$45
601%
upside
Avg. target
$52
705%
upside
High target
$56
772%
upside
3 analyst ratings
3 positive
100%
0 neutral
0%
0 negative
0%
Baird Michael Ulz 22% 1-year accuracy 4 / 18 met price target | 741%upside $54 | Outperform Maintained | 3 Mar 2025 |
HC Wainwright & Co. Edward White 28% 1-year accuracy 40 / 143 met price target | 772%upside $56 | Buy Maintained | 26 Feb 2025 |
RBC Capital Brian Abrahams 17% 1-year accuracy 12 / 72 met price target | 601%upside $45 | Outperform Reiterated | 20 Feb 2025 |
Financial journalist opinion
Based on 3 articles about KPTI published over the past 30 days
Neutral
PRNewsWire
2 weeks ago
XPOVIO® (selinexor) Approved for Commercialization in Indonesia, Further Expanding Antengene's Commercial Presence in APAC
- XPOVIO ® is the first and only approved XPO1 inhibitor in Indonesia. - From the second half of 2024 to now, XPOVIO ® was successively approved in Thailand, Malaysia and Indonesia, significantly expanding Antengene's commercial presence in APAC.

Neutral
PRNewsWire
2 weeks ago
Karyopharm Therapeutics Reports Inducement Grants Under Nasdaq Listing Rule 5635(c)(4)
NEWTON, Mass. , March 3, 2025 /PRNewswire/ -- Karyopharm Therapeutics Inc. (Nasdaq: KPTI), a commercial-stage pharmaceutical company pioneering novel cancer therapies, today announced that the Company granted an aggregate of 3,316 restricted stock units (RSUs) to five newly-hired employees.

Neutral
PRNewsWire
3 weeks ago
Karyopharm Announces 1-for-15 Reverse Stock Split
NEWTON, Mass. , Feb. 24, 2025 /PRNewswire/ -- Karyopharm Therapeutics Inc. (Nasdaq: KPTI), a commercial-stage pharmaceutical company pioneering novel cancer therapies, today announced that it will implement a 1-for-15 reverse stock split of the issued shares of the Company's common stock ("Reverse Stock Split"), effective at 5:00 p.m.

Neutral
Seeking Alpha
1 month ago
Karyopharm Therapeutics Inc. (KPTI) Q4 2024 Earnings Call Transcript
Karyopharm Therapeutics Inc. (NASDAQ:KPTI ) Q4 2024 Earnings Call February 19, 2025 8:00 AM ET Company Participants Brendan Strong - SVP, IR Richard Paulson - President and CEO Reshma Rangwala - CMO & Head of Research Sohanya Cheng - CCO & Head of Business Development Lori Macomber - EVP, CFO, & Treasurer Conference Call Participants Colleen Kusy - Baird Maury Raycroft - Jefferies Unidentified Analyst - Barclays Jonathan Chang - Leerink Partners Unidentified Analyst - RBC Capital Markets Ed White - H.C. Wainwright Operator Good morning.

Negative
Zacks Investment Research
1 month ago
Karyopharm Therapeutics (KPTI) Reports Q4 Loss, Tops Revenue Estimates
Karyopharm Therapeutics (KPTI) came out with a quarterly loss of $0.24 per share versus the Zacks Consensus Estimate of a loss of $0.26. This compares to loss of $0.36 per share a year ago.

Neutral
PRNewsWire
1 month ago
Karyopharm Reports Fourth Quarter and Full Year 2024 Financial Results, Announces Update to Phase 3 XPORT-EC-042 Trial and Highlights Recent Company Progress
– Total Revenue of $145 Million and U.S. XPOVIO® (selinexor) Net Product Revenue of $113 Million for Full Year 2024 – – Top-Line Data Readout from Phase 3 SENTRY Trial Evaluating Selinexor in Combination with Ruxolitinib in Patients with JAKi-Naïve Myelofibrosis Anticipated in 2H 2025; Company on Track to Complete Enrollment in 1H 2025 – – Company Announces Update to Phase 3 XPORT-EC-042 Trial of Selinexor as Maintenance Therapy in Advanced or Recurrent TP53 Wild-Type Endometrial Cancer. Following Dialogue with the FDA Regarding the Evolving Treatment Landscape, Trial to Focus Enrollment on Patients with Either pMMR Tumors or Patients with dMMR Tumors that are Medically Ineligible for Checkpoint Inhibitors.

Neutral
PRNewsWire
1 month ago
Antengene Announces XPOVIO® Approved for Public Health Insurance Coverage in Taiwan Market, Benefiting More Patients with R/R MM in the Region
XPOVIO® is the first XPO1 inhibitor approved in Taiwan for the treatment of adult patients with relapsed/refractory multiple myeloma (R/R MM). After the mainland of China, South Korea, Australia and Singapore, Taiwan market is the fifth APAC market in which XPOVIO® has been approved for public health insurance coverage.

Neutral
PRNewsWire
1 month ago
Karyopharm to Report Fourth Quarter and Full Year 2024 Financial Results on February 19, 2025
-- Conference Call Scheduled for Wednesday, February 19, 2025, at 8:00 a.m. ET -- NEWTON, Mass.

Neutral
PRNewsWire
1 month ago
Karyopharm Therapeutics Reports Inducement Grants Under Nasdaq Listing Rule 5635(c)(4)
NEWTON, Mass. , Feb. 3, 2025 /PRNewswire/ -- Karyopharm Therapeutics Inc. (Nasdaq: KPTI), a commercial-stage pharmaceutical company pioneering novel cancer therapies, today announced that the Company granted an aggregate of 28,000 restricted stock units (RSUs) to three newly-hired employees.

Neutral
PRNewsWire
2 months ago
Karyopharm Announces Preliminary Unaudited 2024 Revenue and 2025 Objectives
– Opportunity to Define a New Myelofibrosis Treatment Paradigm with Top-Line Data Readout from Phase 3 SENTRY Trial Evaluating Selinexor in Combination with Ruxolitinib in Patients with JAKi-Naïve Myelofibrosis Anticipated in 2H 2025; Company On Track to Complete Enrollment in 1H 2025 – – Recently Announced Key Leadership Changes, including the Appointment of Lori Macomber as Chief Financial Officer and Brendan Strong as SVP of Investor Relations and Corporate Communications – – Preliminary Unaudited Full Year 2024 Total Revenue and U.S. XPOVIO® (selinexor) Net Product Revenue Expected to be Approximately $145 Million and $113 Million, Respectively – NEWTON, Mass. , Jan. 13, 2025 /PRNewswire/ -- Karyopharm Therapeutics Inc. (Nasdaq: KPTI), a commercial-stage pharmaceutical company pioneering novel cancer therapies, today announced preliminary unaudited fourth quarter and full year 2024 total revenue and U.S. XPOVIO net product revenue estimates and outlined its 2024 achievements and 2025 objectives.

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