Karyopharm Therapeutics
KPTI
KPTI
52 hedge funds and large institutions have $19.5M invested in Karyopharm Therapeutics in 2025 Q3 according to their latest regulatory filings, with 7 funds opening new positions, 7 increasing their positions, 20 reducing their positions, and 5 closing their positions.
New
Increased
Maintained
Reduced
Closed
more first-time investments, than exits
New positions opened: | Existing positions closed:
more funds holding
Funds holding: →
more capital invested
Capital invested by funds: $ → $
less ownership
Funds ownership: →
26% less call options, than puts
Call options by funds: $5.74M | Put options by funds: $7.74M
65% less repeat investments, than reductions
Existing positions increased: 7 | Existing positions reduced: 20
Holders
52
Holding in Top 10
–
Calls
$5.74M
Puts
$7.74M
Top Buyers
| 1 | +$231K | |
| 2 | +$164K | |
| 3 | +$101K | |
| 4 |
Belvedere Trading
Chicago,
Illinois
|
+$95.2K |
| 5 |
State Street
Boston,
Massachusetts
|
+$85.3K |
Top Sellers
| 1 | -$1.67M | |
| 2 | -$1.11M | |
| 3 | -$1.1M | |
| 4 |
Citadel Advisors
Miami,
Florida
|
-$891K |
| 5 |
PAI
Palo Alto Investors
Palo Alto,
California
|
-$810K |
