Karyopharm Therapeutics
KPTI
KPTI
69 hedge funds and large institutions have $69.6M invested in Karyopharm Therapeutics in 2025 Q4 according to their latest regulatory filings, with 27 funds opening new positions, 19 increasing their positions, 5 reducing their positions, and 10 closing their positions.
New
Increased
Maintained
Reduced
Closed
more repeat investments, than reductions
Existing positions increased: | Existing positions reduced:
more capital invested
Capital invested by funds: $ → $
more first-time investments, than exits
New positions opened: | Existing positions closed:
more funds holding
Funds holding: →
21.2% more ownership
Funds ownership: 34.32% → 55.52% (+21%)
1% more call options, than puts
Call options by funds: $4.81M | Put options by funds: $4.75M
Holders
69
Holding in Top 10
–
Calls
$4.81M
Puts
$4.75M
Top Buyers
| 1 | +$5.69M | |
| 2 | +$5.44M | |
| 3 | +$4.83M | |
| 4 |
IC
Ikarian Capital
Dallas,
Texas
|
+$3.16M |
| 5 |
SCM
Soleus Capital Management
Greenwich,
Connecticut
|
+$2.69M |
Top Sellers
| 1 | -$183K | |
| 2 | -$163K | |
| 3 | -$103K | |
| 4 |
GCP
GSA Capital Partners
London,
United Kingdom
|
-$92K |
| 5 |
Belvedere Trading
Chicago,
Illinois
|
-$89.1K |
