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Karyopharm Therapeutics

118 hedge funds and large institutions have $103M invested in Karyopharm Therapeutics in 2023 Q3 according to their latest regulatory filings, with 16 funds opening new positions, 40 increasing their positions, 29 reducing their positions, and 35 closing their positions.

New
Increased
Maintained
Reduced
Closed

331% more call options, than puts

Call options by funds: $785K | Put options by funds: $182K

38% more repeat investments, than reductions

Existing positions increased: 40 | Existing positions reduced: 29

0.27% less ownership

Funds ownership: 4.77%4.5% (-0.27%)

14% less funds holding

Funds holding: 137118 (-19)

29% less capital invested

Capital invested by funds: $145M → $103M (-$42.2M)

54% less first-time investments, than exits

New positions opened: 16 | Existing positions closed: 35

Holders
118
Holders Change
-19
Holders Change %
-13.87%
% of All Funds
1.87%
Holding in Top 10
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
New
16
Increased
40
Reduced
29
Closed
35
Calls
$785K
Puts
$182K
Net Calls
+$603K
Net Calls Change
+$232K
Name Holding Trade Value Shares
Change
Change in
Stake
BlackRock
1
BlackRock
New York
$14.9M -$674K -30,050 -4%
Vanguard Group
2
Vanguard Group
Pennsylvania
$11.8M +$203K +9,053 +2%
APM
3
Avidity Partners Management
Texas
$11.1M -$107K -4,769 -0.9%
PAI
4
Palo Alto Investors
California
$7.61M
Citadel Advisors
5
Citadel Advisors
Florida
$4.16M -$68.5K -3,053 -1%
Jacobs Levy Equity Management
6
Jacobs Levy Equity Management
New Jersey
$3.15M +$2.51M +111,778 +248%
Geode Capital Management
7
Geode Capital Management
Massachusetts
$3.07M +$224K +10,003 +7%
Marshall Wace
8
Marshall Wace
United Kingdom
$2.93M -$390K -17,386 -11%
State Street
9
State Street
Massachusetts
$2.74M -$253K -11,291 -8%
Goldman Sachs
10
Goldman Sachs
New York
$2.57M +$440K +19,602 +18%
ACM
11
AIGH Capital Management
Maryland
$2.38M
BNP Paribas Financial Markets
12
BNP Paribas Financial Markets
France
$2.23M +$1.8M +79,987 +260%
CWG
13
C WorldWide Group
Denmark
$2.01M
ECM
14
ExodusPoint Capital Management
New York
$1.87M -$1.47M -65,660 -41%
Barclays
15
Barclays
United Kingdom
$1.54M +$68.7K +3,063 +4%
JP Morgan Chase
16
JP Morgan Chase
New York
$1.53M +$1.57M +70,113 +1,176%
CS
17
Candriam SCA
Luxembourg
$1.53M -$441K -19,667 -21%
AA
18
AlphaCentric Advisors
Puerto Rico
$1.51M +$471K +21,000 +39%
Millennium Management
19
Millennium Management
New York
$1.5M -$49.9K -2,222 -3%
TC
20
Tejara Capital
United Kingdom
$1.44M -$99.6K -4,440 -6%
Morgan Stanley
21
Morgan Stanley
New York
$1.4M +$931K +41,477 +147%
Northern Trust
22
Northern Trust
Illinois
$1.32M -$125K -5,558 -8%
UBS Group
23
UBS Group
Switzerland
$1.21M +$702K +31,269 +107%
UOC
24
UBS O'Connor
Illinois
$1.17M +$404K +18,000 +45%
ACM
25
Altium Capital Management
New York
$992K

KPTI Hedge Fund Activity: Q3 2023 in Review

118 of the 6,301 institutional investors tracked by Wall St. Rank reported a position in Karyopharm Therapeutics (KPTI) for Q3 2023, worth a combined $103M — down 29% from $145M a quarter earlier.

Sellers outnumbered buyers: 35 funds closed out of KPTI and 16 opened new positions — a net loss of 19 holders — while 29 trimmed existing stakes and 40 added.

The largest buyer was Jacobs Levy Equity Management, adding an estimated $2.51M. The largest seller was Opaleye Management, exiting entirely with an estimated $3.2M sold.

  • 118 institutional investors held Karyopharm Therapeutics (KPTI) as of Q3 2023, down from 137 in Q2 2023.
  • Funds reported $103M of Karyopharm Therapeutics stock for Q3 2023, down 29% quarter-over-quarter.
  • 16 funds opened new Karyopharm Therapeutics positions in Q3 2023 and 35 closed out, a net change of -19 holders.
  • The largest Karyopharm Therapeutics buyer in Q3 2023 was Jacobs Levy Equity Management, an estimated $2.51M added.
  • The largest Karyopharm Therapeutics seller in Q3 2023 was Opaleye Management, an estimated $3.2M sold.

Based on aggregated 13F filings for Q3 2023.