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Karyopharm Therapeutics
KPTI

Overview Fund Activity

153 hedge funds and large institutions have $608M invested in Karyopharm Therapeutics in 2021 Q2 according to their latest regulatory filings, with 21 funds opening new positions, 54 increasing their positions, 56 reducing their positions, and 38 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
153
Holders Change
-18
Holders Change %
-10.53%
% of All Funds
2.67%
Holding in Top 10
1
Holding in Top 10 Change
–
Holding in Top 10 Change %
–
% of All Funds
0.02%
New
21
Increased
54
Reduced
56
Closed
38
Calls
$4.62M
Puts
$14.1M
Net Calls
-$9.52M
Net Calls Change
-$8.17M

Top Buyers

1
RCMNY
Rubric Capital Management (New York)
New York
$43.9M
2
BlackRock
BlackRock
New York
$90.6M
3
LOAMS
Lombard Odier Asset Management (Switzerland)
Switzerland
$14.2M
4
State Street
State Street
Massachusetts
$60M
5
BNP Paribas Financial Markets
BNP Paribas Financial Markets
France
$4.05M

Top Sellers

1
Adage Capital Partners
Adage Capital Partners
Massachusetts
$0
2
Wellington Management Group
Wellington Management Group
Massachusetts
$6.15M
3
LCM
Laurion Capital Management
New York
$627K
4
CLOS
Compagnie Lombard Odier SCmA
Switzerland
$0
5
Two Sigma Investments
Two Sigma Investments
New York
$8.73M
Name Holding Trade Value Shares
Change 		Shares
Change %
BlackRock
1
BlackRock
New York
$90.6M +$10.6M +68,767 +13%
State Street
2
State Street
Massachusetts
$60M +$5M +32,285 +9%
PAI
3
Palo Alto Investors
California
$55.6M +$200K +1,293 +0.4%
RCMNY
4
Rubric Capital Management (New York)
New York
$43.9M +$43.9M +283,547 New
Vanguard Group
5
Vanguard Group
Pennsylvania
$37.3M +$587K +3,792 +2%
Alkeon Capital Management
6
Alkeon Capital Management
New York
$27.5M -$51.9K -335 -0.2%
DMPV
7
Delphi Management Partners VIII
California
$23.4M – – –
Morgan Stanley
8
Morgan Stanley
New York
$17M -$576K -3,720 -3%
FCM
9
Frontier Capital Management
Massachusetts
$15.4M +$2.76M +17,821 +22%
RHJA
10
Rice Hall James & Associates
California
$14.5M -$1.59M -10,243 -10%
LOAMS
11
Lombard Odier Asset Management (Switzerland)
Switzerland
$14.2M +$5.64M +36,446 +66%
CWG
12
C WorldWide Group
Denmark
$12.4M – – –
Geode Capital Management
13
Geode Capital Management
Massachusetts
$12.3M +$501K +3,237 +4%
Nuveen Asset Management
14
Nuveen Asset Management
Illinois
$11.7M +$2.13M +13,757 +22%
Goldman Sachs
15
Goldman Sachs
New York
$10.4M -$2.13M -13,750 -17%
JGC
16
J. Goldman & Co
New York
$10.4M -$3.37M -21,743 -25%
Two Sigma Advisers
17
Two Sigma Advisers
New York
$10.1M +$745K +4,813 +8%
Two Sigma Investments
18
Two Sigma Investments
New York
$8.73M -$6.67M -43,101 -43%
HRCM
19
Hood River Capital Management
Florida
$8.28M -$479K -3,097 -5%
Northern Trust
20
Northern Trust
Illinois
$8.11M +$415K +2,683 +5%
GIM
21
Granahan Investment Management
Massachusetts
$7.55M +$425K +2,744 +6%
CS
22
Candriam SCA
Luxembourg
$7.41M -$2.41M -15,593 -25%
Wellington Management Group
23
Wellington Management Group
Massachusetts
$6.15M -$13.6M -88,118 -69%
AAM
24
AMI Asset Management
California
$5.31M +$133K +862 +3%
JPMorgan Chase & Co
25
JPMorgan Chase & Co
New York
$4.99M +$1.48M +9,565 +42%
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