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Karyopharm Therapeutics
KPTI

Overview Fund Activity

81 hedge funds and large institutions have $701M invested in Karyopharm Therapeutics in 2014 Q4 according to their latest regulatory filings, with 19 funds opening new positions, 29 increasing their positions, 19 reducing their positions, and 8 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
81
Holders Change
+10
Holders Change %
+14.08%
% of All Funds
2.16%
Holding in Top 10
2
Holding in Top 10 Change
–
Holding in Top 10 Change %
–
% of All Funds
0.05%
New
19
Increased
29
Reduced
19
Closed
8
Calls
$1.34M
Puts
$1.65M
Net Calls
-$306K
Net Calls Change
-$90K

Top Buyers

1
Fidelity Investments
Fidelity Investments
Massachusetts
+$31.7M
2
BFA
BlackRock Fund Advisors
California
+$16.6M
3
Franklin Resources
Franklin Resources
California
+$8.71M
4
State Street
State Street
Massachusetts
+$4.02M
5
UBS AM
UBS AM
Illinois
+$3.9M

Top Sellers

1
PHS
PFM Health Sciences
California
-$10.3M
2
BA
BlackRock Advisors
Delaware
-$4.37M
3
Wellington Management Group
Wellington Management Group
Massachusetts
-$4.18M
4
Lord, Abbett & Co
Lord, Abbett & Co
New Jersey
-$3.65M
5
Balyasny Asset Management
Balyasny Asset Management
Illinois
-$3.48M
Name Holding Trade Value Shares
Change 		Shares
Change %
Fidelity Investments
1
Fidelity Investments
Massachusetts
$184M +$31.7M +56,403 +21%
Franklin Resources
2
Franklin Resources
California
$174M +$8.71M +15,517 +5%
FCMI
3
Foresite Capital Management I
California
$37.4M -$2.91M -5,190 -7%
PHS
4
PFM Health Sciences
California
$31.8M -$10.3M -18,368 -24%
BFA
5
BlackRock Fund Advisors
California
$28.6M +$16.6M +29,533 +137%
State Street
6
State Street
Massachusetts
$25.2M +$4.02M +7,163 +19%
BA
7
BlackRock Advisors
Delaware
$22.7M -$4.37M -7,792 -16%
SAM
8
Sectoral Asset Management
Quebec, Canada
$19.8M +$1.56M +2,772 +9%
AllianceBernstein
9
AllianceBernstein
Tennessee
$15.7M -$2M -3,564 -11%
Vanguard Group
10
Vanguard Group
Pennsylvania
$15.6M +$1.29M +2,300 +9%
CAM
11
Cormorant Asset Management
Massachusetts
$14.4M – – –
CS
12
Candriam SCA
Luxembourg
$11.2M +$11.2M +19,867 New
BIT
13
BlackRock Institutional Trust
California
$8.2M +$2.92M +5,204 +55%
Wellington Management Group
14
Wellington Management Group
Massachusetts
$8.09M -$4.18M -7,452 -34%
BG
15
BlackRock Group
United Kingdom
$7.86M -$783K -1,394 -9%
GC
16
Guggenheim Capital
Illinois
$7.08M +$3.9M +6,941 +122%
UBS Group
17
UBS Group
Switzerland
$6.95M +$6.95M +12,383 New
TG
18
TCW Group
California
$6.29M +$1.16M +2,063 +23%
Northern Trust
19
Northern Trust
Illinois
$5.56M -$100K -178 -2%
TCM
20
Tekla Capital Management
Massachusetts
$5.16M +$1.34M +2,386 +35%
NLVP
21
New Leaf Venture Partners
New York
$4.74M +$4.74M +8,446 New
UBS AM
22
UBS AM
Illinois
$4.2M +$3.9M +6,947 +1,286%
Deutsche Bank
23
Deutsche Bank
Germany
$4.02M +$1.03M +1,833 +34%
PC
24
PointState Capital
New York
$3.74M – – –
BBA
25
Baker Bros. Advisors
New York
$3.52M – – –
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