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Karyopharm Therapeutics
KPTI

Overview Fund Activity

113 hedge funds and large institutions have $113M invested in Karyopharm Therapeutics in 2024 Q1 according to their latest regulatory filings, with 20 funds opening new positions, 36 increasing their positions, 31 reducing their positions, and 22 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
113
Holders Change
-4
Holders Change %
-3.42%
% of All Funds
1.64%
Holding in Top 10
–
Holding in Top 10 Change
–
Holding in Top 10 Change %
–
% of All Funds
–
New
20
Increased
36
Reduced
31
Closed
22
Calls
$330K
Puts
$321K
Net Calls
+$9K
Net Calls Change
-$421K

Top Buyers

1
EP
Eversept Partners
New York
+$7.57M
2
Adage Capital Partners
Adage Capital Partners
Massachusetts
+$2.77M
3
Marshall Wace
Marshall Wace
United Kingdom
+$1.01M
4
D.E. Shaw & Co
D.E. Shaw & Co
New York
+$522K
5
State Street
State Street
Massachusetts
+$350K

Top Sellers

1
Morgan Stanley
Morgan Stanley
New York
-$2.11M
2
Renaissance Technologies
Renaissance Technologies
New York
-$1.6M
3
GCP
GSA Capital Partners
United Kingdom
-$1.57M
4
BlackRock
BlackRock
New York
-$942K
5
TC
Tejara Capital
United Kingdom
-$892K
Name Holding Trade Value Shares
Change 		Shares
Change %
BlackRock
1
BlackRock
New York
$14.3M -$942K -41,600 -6%
Vanguard Group
2
Vanguard Group
Pennsylvania
$12.6M -$561K -24,784 -4%
APM
3
Avidity Partners Management
Texas
$12.5M – – –
PAI
4
Palo Alto Investors
California
$7.7M – – –
EP
5
Eversept Partners
New York
$7.57M +$7.57M +334,421 New
Adage Capital Partners
6
Adage Capital Partners
Massachusetts
$5.29M +$2.77M +122,446 +110%
Citadel Advisors
7
Citadel Advisors
Florida
$4.69M +$5.55K +245 +0.1%
Marshall Wace
8
Marshall Wace
United Kingdom
$3.92M +$1.01M +44,588 +35%
Geode Capital Management
9
Geode Capital Management
Massachusetts
$3.81M +$208K +9,178 +6%
State Street
10
State Street
Massachusetts
$3.45M +$350K +15,468 +11%
BNP Paribas Financial Markets
11
BNP Paribas Financial Markets
France
$2.68M +$6.91K +305 +0.3%
Goldman Sachs
12
Goldman Sachs
New York
$2.28M +$320K +14,111 +16%
CWG
13
C WorldWide Group
Denmark
$2.27M – – –
JPMorgan Chase & Co
14
JPMorgan Chase & Co
New York
$2.08M +$297K +13,098 +17%
Deutsche Bank
15
Deutsche Bank
Germany
$2M -$3.06K -135 -0.2%
GCP
16
GSA Capital Partners
United Kingdom
$1.96M -$1.57M -69,256 -44%
Millennium Management
17
Millennium Management
New York
$1.79M -$526K -23,225 -23%
AA
18
AlphaCentric Advisors
Puerto Rico
$1.7M – – –
D.E. Shaw & Co
19
D.E. Shaw & Co
New York
$1.45M +$522K +23,040 +56%
Northern Trust
20
Northern Trust
Illinois
$1.45M -$56.4K -2,490 -4%
Renaissance Technologies
21
Renaissance Technologies
New York
$1.37M -$1.6M -70,505 -54%
Barclays
22
Barclays
United Kingdom
$1.35M -$117K -5,150 -8%
ACM
23
Altium Capital Management
New York
$1.12M – – –
UOC
24
UBS O'Connor
Illinois
$1.09M -$121K -5,333 -10%
SCM
25
Silverarc Capital Management
Massachusetts
$843K -$5.28K -233 -0.6%
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