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Karyopharm Therapeutics

89 hedge funds and large institutions have $248M invested in Karyopharm Therapeutics in 2015 Q3 according to their latest regulatory filings, with 13 funds opening new positions, 37 increasing their positions, 25 reducing their positions, and 13 closing their positions.

New
Increased
Maintained
Reduced
Closed

330% more call options, than puts

Call options by funds: $9.77M | Put options by funds: $2.27M

48% more repeat investments, than reductions

Existing positions increased: 37 | Existing positions reduced: 25

0% more funds holding

Funds holding: 8989 (0)

0% more first-time investments, than exits

New positions opened: 13 | Existing positions closed: 13

59% less capital invested

Capital invested by funds: $610M → $248M (-$362M)

100% less funds holding in top 10

Funds holding in top 10: 10 (-1)

Holders
89
Holders Change
Holders Change %
0%
% of All Funds
2.48%
Holding in Top 10
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-100%
% of All Funds
New
13
Increased
37
Reduced
25
Closed
13
Calls
$9.77M
Puts
$2.27M
Net Calls
+$7.5M
Net Calls Change
+$8.8M
Name Holding Trade Value Shares
Change
Change in
Stake
Franklin Resources
1
Franklin Resources
California
$59.1M +$16.2M +60,443 +19%
Fidelity Investments
2
Fidelity Investments
Massachusetts
$56.4M +$43.6K +163 +0%
PAI
3
Palo Alto Investors
California
$32.5M +$24.1M +90,281 +78%
BFA
4
BlackRock Fund Advisors
California
$11.7M +$906K +3,386 +5%
Millennium Management
5
Millennium Management
New York
$10.8M +$11.8M +44,085 +181%
TCM
6
Tekla Capital Management
Massachusetts
$9.68M +$7.88M +29,460 +93%
SAM
7
Sectoral Asset Management
Quebec, Canada
$7.51M
Vanguard Group
8
Vanguard Group
Pennsylvania
$7.35M -$43.6K -163 -0.3%
Citadel Advisors
9
Citadel Advisors
Florida
$6.09M +$2.23M +8,346 +28%
BIT
10
BlackRock Institutional Trust
California
$5.37M +$825K +3,084 +10%
State Street
11
State Street
Massachusetts
$3.22M -$16.5M -61,880 -75%
CAM
12
Cormorant Asset Management
Massachusetts
$3.17M
Northern Trust
13
Northern Trust
Illinois
$2.54M +$1.2M +4,489 +39%
BBA
14
Baker Bros. Advisors
New York
$2.29M
Wellington Management Group
15
Wellington Management Group
Massachusetts
$1.79M +$189K +708 +7%
CS
16
Candriam SCA
Luxembourg
$1.7M +$501K +1,873 +21%
FLAM
17
First Light Asset Management
Minnesota
$1.63M +$2.76M +10,314 New
Geode Capital Management
18
Geode Capital Management
Massachusetts
$1.43M +$75.7K +283 +3%
ARTA
19
A.R.T. Advisors
New York
$1.43M +$2.43M +9,074 New
Morgan Stanley
20
Morgan Stanley
New York
$1.41M +$1.83M +6,846 +334%
GC
21
Guggenheim Capital
Illinois
$1.4M -$109K -406 -4%
AC
22
Ascend Capital
California
$1.31M -$445K -1,665 -17%
SIP
23
Stoneridge Investment Partners
Pennsylvania
$1.1M +$260K +972 +16%
Bank of New York Mellon
24
Bank of New York Mellon
New York
$1.1M -$157K -587 -8%
Deutsche Bank
25
Deutsche Bank
Germany
$914K +$93.3K +349 +6%

KPTI Hedge Fund Activity: Q3 2015 in Review

89 of the 3,582 institutional investors tracked by Wall St. Rank reported a position in Karyopharm Therapeutics (KPTI) for Q3 2015, worth a combined $248M — down 59% from $610M a quarter earlier.

Fund positioning in KPTI was balanced in Q3 2015: 13 funds opened new positions, 13 closed out, 37 added to existing stakes and 25 trimmed.

The largest buyer was Palo Alto Investors, adding an estimated $24.1M. The largest seller was PFM Health Sciences, exiting entirely with an estimated $22.4M sold.

  • 89 institutional investors held Karyopharm Therapeutics (KPTI) as of Q3 2015, unchanged from Q2 2015.
  • Funds reported $248M of Karyopharm Therapeutics stock for Q3 2015, down 59% quarter-over-quarter.
  • 13 funds opened new Karyopharm Therapeutics positions in Q3 2015 and 13 closed out, a net change of 0 holders.
  • The largest Karyopharm Therapeutics buyer in Q3 2015 was Palo Alto Investors, an estimated $24.1M added.
  • The largest Karyopharm Therapeutics seller in Q3 2015 was PFM Health Sciences, an estimated $22.4M sold.

Based on aggregated 13F filings for Q3 2015.