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Karyopharm Therapeutics
KPTI

Overview Fund Activity

79 hedge funds and large institutions have $225M invested in Karyopharm Therapeutics in 2016 Q3 according to their latest regulatory filings, with 11 funds opening new positions, 29 increasing their positions, 19 reducing their positions, and 7 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
79
Holders Change
+4
Holders Change %
+5.33%
% of All Funds
2.11%
Holding in Top 10
–
Holding in Top 10 Change
–
Holding in Top 10 Change %
–
% of All Funds
–
New
11
Increased
29
Reduced
19
Closed
7
Calls
$762K
Puts
$186K
Net Calls
+$576K
Net Calls Change
+$442K

Top Buyers

1
Wellington Management Group
Wellington Management Group
Massachusetts
$41.4M
2
Millennium Management
Millennium Management
New York
$8.48M
3
CS
Candriam SCA
Luxembourg
$2.63M
4
BFA
BlackRock Fund Advisors
California
$11.2M
5
Vanguard Group
Vanguard Group
Pennsylvania
$8.58M

Top Sellers

1
NLVP
New Leaf Venture Partners
New York
$0
2
PAI
Palo Alto Investors
California
$30M
3
TC
TFS Capital
Pennsylvania
$0
4
SIP
Stoneridge Investment Partners
Pennsylvania
$154K
5
Bank of New York Mellon
Bank of New York Mellon
New York
$854K
Name Holding Trade Value Shares
Change 		Shares
Change %
Fidelity Investments
1
Fidelity Investments
Massachusetts
$52.2M – – –
Wellington Management Group
2
Wellington Management Group
Massachusetts
$41.4M +$26.9M +184,556 +186%
Franklin Resources
3
Franklin Resources
California
$31.9M -$8.9K -61 -0%
PAI
4
Palo Alto Investors
California
$30M -$521K -3,573 -2%
BFA
5
BlackRock Fund Advisors
California
$11.2M +$754K +5,165 +7%
Vanguard Group
6
Vanguard Group
Pennsylvania
$8.58M +$634K +4,344 +8%
Millennium Management
7
Millennium Management
New York
$8.48M +$1.53M +10,517 +22%
BIT
8
BlackRock Institutional Trust
California
$5.25M +$80.4K +551 +2%
TCM
9
Tekla Capital Management
Massachusetts
$4.87M – – –
State Street
10
State Street
Massachusetts
$3.71M +$94.6K +648 +3%
JPMorgan Chase & Co
11
JPMorgan Chase & Co
New York
$3.64M +$117K +801 +3%
Northern Trust
12
Northern Trust
Illinois
$2.65M +$144K +989 +6%
CS
13
Candriam SCA
Luxembourg
$2.63M +$1.07M +7,333 +69%
BBA
14
Baker Bros. Advisors
New York
$2.11M – – –
Geode Capital Management
15
Geode Capital Management
Massachusetts
$1.43M +$29.3K +201 +2%
BIM
16
BlackRock Investment Management
Delaware
$992K +$81.7K +560 +9%
Deutsche Bank
17
Deutsche Bank
Germany
$951K +$129K +887 +16%
Bank of New York Mellon
18
Bank of New York Mellon
New York
$854K -$134K -917 -14%
MOACM
19
Mutual of America Capital Management
New York
$851K – – –
RhumbLine Advisers
20
RhumbLine Advisers
Massachusetts
$794K +$167K +1,142 +27%
Charles Schwab
21
Charles Schwab
California
$617K +$27.9K +191 +5%
Dimensional Fund Advisors
22
Dimensional Fund Advisors
Texas
$568K +$568K +3,889 New
PCM
23
Piermont Capital Management
Missouri
$507K +$507K +3,472 New
California State Teachers Retirement System (CalSTRS)
24
California State Teachers Retirement System (CalSTRS)
California
$485K +$2.92K +20 +0.6%
Goldman Sachs
25
Goldman Sachs
New York
$472K +$70.5K +483 +18%
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