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Karyopharm Therapeutics

75 hedge funds and large institutions have $135M invested in Karyopharm Therapeutics in 2016 Q2 according to their latest regulatory filings, with 11 funds opening new positions, 31 increasing their positions, 18 reducing their positions, and 13 closing their positions.

New
Increased
Maintained
Reduced
Closed

76% more call options, than puts

Call options by funds: $310K | Put options by funds: $176K

72% more repeat investments, than reductions

Existing positions increased: 31 | Existing positions reduced: 18

3% less funds holding

Funds holding: 7775 (-2)

15% less first-time investments, than exits

New positions opened: 11 | Existing positions closed: 13

28% less capital invested

Capital invested by funds: $187M → $135M (-$53M)

100% less funds holding in top 10

Funds holding in top 10: 10 (-1)

Holders
75
Holders Change
-2
Holders Change %
-2.6%
% of All Funds
2%
Holding in Top 10
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-100%
% of All Funds
New
11
Increased
31
Reduced
18
Closed
13
Calls
$310K
Puts
$176K
Net Calls
+$134K
Net Calls Change
-$448K
Name Holding Trade Value Shares
Change
Change in
Stake
Fidelity Investments
1
Fidelity Investments
Massachusetts
$36M
Franklin Resources
2
Franklin Resources
California
$22M -$8.71M -67,071 -23%
PAI
3
Palo Alto Investors
California
$21.1M +$358K +2,753 +1%
Wellington Management Group
4
Wellington Management Group
Massachusetts
$10M +$1.92M +14,744 +17%
BFA
5
BlackRock Fund Advisors
California
$7.18M +$103K +794 +1%
Vanguard Group
6
Vanguard Group
Pennsylvania
$5.48M +$1.11M +8,515 +19%
Millennium Management
7
Millennium Management
New York
$4.79M -$5.13M -39,486 -45%
BIT
8
BlackRock Institutional Trust
California
$3.56M +$142K +1,093 +3%
TCM
9
Tekla Capital Management
Massachusetts
$3.36M
State Street
10
State Street
Massachusetts
$2.49M +$90.3K +695 +3%
JP Morgan Chase
11
JP Morgan Chase
New York
$2.43M +$708K +5,452 +29%
Northern Trust
12
Northern Trust
Illinois
$1.73M +$80.8K +622 +4%
NLVP
13
New Leaf Venture Partners
New York
$1.5M +$1.83M +14,048 +1,724%
BBA
14
Baker Bros. Advisors
New York
$1.46M
CS
15
Candriam SCA
Luxembourg
$1.07M -$234K -1,800 -14%
Geode Capital Management
16
Geode Capital Management
Massachusetts
$962K +$41.2K +317 +3%
Bank of New York Mellon
17
Bank of New York Mellon
New York
$682K +$36.2K +279 +4%
BIM
18
BlackRock Investment Management
Delaware
$628K +$103K +791 +15%
MOACM
19
Mutual of America Capital Management
New York
$587K
Deutsche Bank
20
Deutsche Bank
Germany
$567K -$155K -1,190 -17%
TCIM
21
TIAA CREF Investment Management
New York
$512K +$29.8K +229 +5%
RhumbLine Advisers
22
RhumbLine Advisers
Massachusetts
$433K +$365K +2,808 +189%
Charles Schwab
23
Charles Schwab
California
$406K +$7.67K +59 +1%
Bank of America
24
Bank of America
North Carolina
$385K -$3.25K -25 -0.7%
TC
25
TFS Capital
Pennsylvania
$335K +$432K +3,326 New

KPTI Hedge Fund Activity: Q2 2016 in Review

75 of the 3,749 institutional investors tracked by Wall St. Rank reported a position in Karyopharm Therapeutics (KPTI) for Q2 2016, worth a combined $135M — down 28% from $187M a quarter earlier.

Sellers outnumbered buyers: 13 funds closed out of KPTI and 11 opened new positions — a net loss of 2 holders — while 18 trimmed existing stakes and 31 added.

The largest buyer was Wellington Management Group, adding an estimated $1.92M. The largest seller was Franklin Resources, cutting an estimated $8.71M.

  • 75 institutional investors held Karyopharm Therapeutics (KPTI) as of Q2 2016, down from 77 in Q1 2016.
  • Funds reported $135M of Karyopharm Therapeutics stock for Q2 2016, down 28% quarter-over-quarter.
  • 11 funds opened new Karyopharm Therapeutics positions in Q2 2016 and 13 closed out, a net change of -2 holders.
  • The largest Karyopharm Therapeutics buyer in Q2 2016 was Wellington Management Group, an estimated $1.92M added.
  • The largest Karyopharm Therapeutics seller in Q2 2016 was Franklin Resources, an estimated $8.71M sold.

Based on aggregated 13F filings for Q2 2016.