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Karyopharm Therapeutics
KPTI

Overview Fund Activity

75 hedge funds and large institutions have $135M invested in Karyopharm Therapeutics in 2016 Q2 according to their latest regulatory filings, with 11 funds opening new positions, 31 increasing their positions, 18 reducing their positions, and 13 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
75
Holders Change
-2
Holders Change %
-2.6%
% of All Funds
2%
Holding in Top 10
–
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-100%
% of All Funds
–
New
11
Increased
31
Reduced
18
Closed
13
Calls
$310K
Puts
$176K
Net Calls
+$134K
Net Calls Change
-$448K

Top Buyers

1
Wellington Management Group
Wellington Management Group
Massachusetts
$10M
2
NLVP
New Leaf Venture Partners
New York
$1.5M
3
Vanguard Group
Vanguard Group
Pennsylvania
$5.48M
4
JPMorgan Chase & Co
JPMorgan Chase & Co
New York
$2.43M
5
TC
TFS Capital
Pennsylvania
$335K

Top Sellers

1
Franklin Resources
Franklin Resources
California
$22M
2
Millennium Management
Millennium Management
New York
$4.79M
3
GC
Guggenheim Capital
Illinois
$0
4
ARTA
A.R.T. Advisors
New York
$0
5
OPPM
Opus Point Partners Management
New York
$0
Name Holding Trade Value Shares
Change 		Shares
Change %
Fidelity Investments
1
Fidelity Investments
Massachusetts
$36M – – –
Franklin Resources
2
Franklin Resources
California
$22M -$6.75M -67,071 -23%
PAI
3
Palo Alto Investors
California
$21.1M +$277K +2,753 +1%
Wellington Management Group
4
Wellington Management Group
Massachusetts
$10M +$1.48M +14,744 +17%
BFA
5
BlackRock Fund Advisors
California
$7.18M +$79.9K +794 +1%
Vanguard Group
6
Vanguard Group
Pennsylvania
$5.48M +$857K +8,515 +19%
Millennium Management
7
Millennium Management
New York
$4.79M -$3.97M -39,486 -45%
BIT
8
BlackRock Institutional Trust
California
$3.56M +$110K +1,093 +3%
TCM
9
Tekla Capital Management
Massachusetts
$3.36M – – –
State Street
10
State Street
Massachusetts
$2.49M +$69.9K +695 +3%
JPMorgan Chase & Co
11
JPMorgan Chase & Co
New York
$2.43M +$549K +5,452 +29%
Northern Trust
12
Northern Trust
Illinois
$1.73M +$62.6K +622 +4%
NLVP
13
New Leaf Venture Partners
New York
$1.5M +$1.41M +14,048 +1,724%
BBA
14
Baker Bros. Advisors
New York
$1.46M – – –
CS
15
Candriam SCA
Luxembourg
$1.07M -$181K -1,800 -14%
Geode Capital Management
16
Geode Capital Management
Massachusetts
$962K +$31.9K +317 +3%
Bank of New York Mellon
17
Bank of New York Mellon
New York
$682K +$28.1K +279 +4%
BIM
18
BlackRock Investment Management
Delaware
$628K +$79.6K +791 +15%
MOACM
19
Mutual of America Capital Management
New York
$587K – – –
Deutsche Bank
20
Deutsche Bank
Germany
$567K -$120K -1,190 -17%
TCIM
21
TIAA CREF Investment Management
New York
$512K +$23K +229 +5%
RhumbLine Advisers
22
RhumbLine Advisers
Massachusetts
$433K +$283K +2,808 +189%
Charles Schwab
23
Charles Schwab
California
$406K +$5.94K +59 +1%
Bank of America
24
Bank of America
North Carolina
$385K -$2.52K -25 -0.7%
TC
25
TFS Capital
Pennsylvania
$335K +$335K +3,326 New
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