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Karyopharm Therapeutics

77 hedge funds and large institutions have $187M invested in Karyopharm Therapeutics in 2016 Q1 according to their latest regulatory filings, with 8 funds opening new positions, 17 increasing their positions, 33 reducing their positions, and 16 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
77
Holders Change
-8
Holders Change %
-9.41%
% of All Funds
2.05%
Holding in Top 10
1
Holding in Top 10 Change
+1
Holding in Top 10 Change %
%
% of All Funds
0.03%
New
8
Increased
17
Reduced
33
Closed
16
Calls
$803K
Puts
$221K
Net Calls
+$582K
Net Calls Change
+$108K
Name Holding Trade Value Shares
Change
Shares
Change %
Fidelity Investments
1
Fidelity Investments
Massachusetts
$47.8M
Franklin Resources
2
Franklin Resources
California
$38.2M -$7.89M -58,985 -17%
PAI
3
Palo Alto Investors
California
$27.6M -$129K -967 -0.5%
Millennium Management
4
Millennium Management
New York
$11.7M +$107K +803 +0.9%
Wellington Management Group
5
Wellington Management Group
Massachusetts
$11.3M +$9.78M +73,068 +632%
BFA
6
BlackRock Fund Advisors
California
$9.44M +$163K +1,222 +2%
Vanguard Group
7
Vanguard Group
Pennsylvania
$6.14M -$119K -889 -2%
BIT
8
BlackRock Institutional Trust
California
$4.59M -$48.6K -363 -1%
TCM
9
Tekla Capital Management
Massachusetts
$4.46M
State Street
10
State Street
Massachusetts
$3.22M +$177K +1,319 +6%
JPMorgan Chase & Co
11
JPMorgan Chase & Co
New York
$2.5M +$562K +4,198 +29%
Northern Trust
12
Northern Trust
Illinois
$2.21M -$13.5K -101 -0.6%
BBA
13
Baker Bros. Advisors
New York
$1.94M
CS
14
Candriam SCA
Luxembourg
$1.66M -$36.3K -273 -2%
Deutsche Bank
15
Deutsche Bank
Germany
$913K -$13.4K -100 -1%
Bank of New York Mellon
16
Bank of New York Mellon
New York
$869K -$61.7K -461 -7%
SIP
17
Stoneridge Investment Partners
Pennsylvania
$840K -$113K -845 -12%
MOACM
18
Mutual of America Capital Management
New York
$780K -$5.35K -40 -0.7%
GC
19
Guggenheim Capital
Illinois
$765K -$263K -1,967 -26%
BIM
20
BlackRock Investment Management
Delaware
$729K +$12.4K +93 +2%
New York State Common Retirement Fund
21
New York State Common Retirement Fund
New York
$725K
TCIM
22
TIAA CREF Investment Management
New York
$650K -$29.7K -222 -4%
ARTA
23
A.R.T. Advisors
New York
$599K -$87.2K -652 -13%
Charles Schwab
24
Charles Schwab
California
$532K +$9.51K +71 +2%
Bank of America
25
Bank of America
North Carolina
$514K -$136K -1,021 -21%