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Karyopharm Therapeutics

77 hedge funds and large institutions have $187M invested in Karyopharm Therapeutics in 2016 Q1 according to their latest regulatory filings, with 8 funds opening new positions, 17 increasing their positions, 33 reducing their positions, and 16 closing their positions.

New
Increased
Maintained
Reduced
Closed

263% more call options, than puts

Call options by funds: $803K | Put options by funds: $221K

9% less funds holding

Funds holding: 8577 (-8)

34% less capital invested

Capital invested by funds: $285M → $187M (-$97.6M)

48% less repeat investments, than reductions

Existing positions increased: 17 | Existing positions reduced: 33

50% less first-time investments, than exits

New positions opened: 8 | Existing positions closed: 16

Holders
77
Holders Change
-8
Holders Change %
-9.41%
% of All Funds
2.05%
Holding in Top 10
1
Holding in Top 10 Change
+1
Holding in Top 10 Change %
% of All Funds
0.03%
New
8
Increased
17
Reduced
33
Closed
16
Calls
$803K
Puts
$221K
Net Calls
+$582K
Net Calls Change
+$108K
Name Holding Trade Value Shares
Change
Change in
Stake
Fidelity Investments
1
Fidelity Investments
Massachusetts
$47.8M
Franklin Resources
2
Franklin Resources
California
$38.2M -$6.51M -58,985 -17%
PAI
3
Palo Alto Investors
California
$27.6M -$107K -967 -0.5%
Millennium Management
4
Millennium Management
New York
$11.7M +$88.6K +803 +0.9%
Wellington Management Group
5
Wellington Management Group
Massachusetts
$11.3M +$8.06M +73,068 +632%
BFA
6
BlackRock Fund Advisors
California
$9.44M +$135K +1,222 +2%
Vanguard Group
7
Vanguard Group
Pennsylvania
$6.14M -$98.1K -889 -2%
BIT
8
BlackRock Institutional Trust
California
$4.59M -$40.1K -363 -1%
TCM
9
Tekla Capital Management
Massachusetts
$4.46M
State Street
10
State Street
Massachusetts
$3.22M +$146K +1,319 +6%
JP Morgan Chase
11
JP Morgan Chase
New York
$2.5M +$463K +4,198 +29%
Northern Trust
12
Northern Trust
Illinois
$2.21M -$11.1K -101 -0.6%
BBA
13
Baker Bros. Advisors
New York
$1.94M
CS
14
Candriam SCA
Luxembourg
$1.66M -$30.1K -273 -2%
Deutsche Bank
15
Deutsche Bank
Germany
$913K -$11K -100 -1%
Bank of New York Mellon
16
Bank of New York Mellon
New York
$869K -$50.9K -461 -7%
SIP
17
Stoneridge Investment Partners
Pennsylvania
$840K -$93.3K -845 -12%
MOACM
18
Mutual of America Capital Management
New York
$780K -$4.42K -40 -0.7%
GC
19
Guggenheim Capital
Illinois
$765K -$217K -1,967 -26%
BIM
20
BlackRock Investment Management
Delaware
$729K +$10.3K +93 +2%
New York State Common Retirement Fund
21
New York State Common Retirement Fund
New York
$725K
TCIM
22
TIAA CREF Investment Management
New York
$650K -$24.5K -222 -4%
ARTA
23
A.R.T. Advisors
New York
$599K -$72K -652 -13%
Charles Schwab
24
Charles Schwab
California
$532K +$7.84K +71 +2%
Bank of America
25
Bank of America
North Carolina
$514K -$113K -1,021 -21%

KPTI Hedge Fund Activity: Q1 2016 in Review

77 of the 3,753 institutional investors tracked by Wall St. Rank reported a position in Karyopharm Therapeutics (KPTI) for Q1 2016, worth a combined $187M — down 34% from $285M a quarter earlier.

Sellers outnumbered buyers: 16 funds closed out of KPTI and 8 opened new positions — a net loss of 8 holders — while 33 trimmed existing stakes and 17 added.

The largest buyer was Wellington Management Group, adding an estimated $8.06M. The largest seller was Franklin Resources, cutting an estimated $6.51M.

  • 77 institutional investors held Karyopharm Therapeutics (KPTI) as of Q1 2016, down from 85 in Q4 2015.
  • Funds reported $187M of Karyopharm Therapeutics stock for Q1 2016, down 34% quarter-over-quarter.
  • 8 funds opened new Karyopharm Therapeutics positions in Q1 2016 and 16 closed out, a net change of -8 holders.
  • The largest Karyopharm Therapeutics buyer in Q1 2016 was Wellington Management Group, an estimated $8.06M added.
  • The largest Karyopharm Therapeutics seller in Q1 2016 was Franklin Resources, an estimated $6.51M sold.

Based on aggregated 13F filings for Q1 2016.