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Karyopharm Therapeutics

90 hedge funds and large institutions have $298M invested in Karyopharm Therapeutics in 2017 Q4 according to their latest regulatory filings, with 18 funds opening new positions, 32 increasing their positions, 25 reducing their positions, and 5 closing their positions.

New
Increased
Maintained
Reduced
Closed

393% more call options, than puts

Call options by funds: $1.19M | Put options by funds: $242K

260% more first-time investments, than exits

New positions opened: 18 | Existing positions closed: 5

28% more repeat investments, than reductions

Existing positions increased: 32 | Existing positions reduced: 25

17% more funds holding

Funds holding: 7790 (+13)

0.32% more ownership

Funds ownership: 4.06%4.38% (+0.32%)

6% less capital invested

Capital invested by funds: $316M → $298M (-$17.9M)

Holders
90
Holders Change
+13
Holders Change %
+16.88%
% of All Funds
2.04%
Holding in Top 10
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
New
18
Increased
32
Reduced
25
Closed
5
Calls
$1.19M
Puts
$242K
Net Calls
+$951K
Net Calls Change
-$227K
Name Holding Trade Value Shares
Change
Change in
Stake
Wellington Management Group
1
Wellington Management Group
Massachusetts
$58M -$2.63M -16,374 -4%
Fidelity Investments
2
Fidelity Investments
Massachusetts
$38.2M -$265K -1,653 -0.6%
PAI
3
Palo Alto Investors
California
$34M +$491K +3,057 +1%
Point72 Asset Management
4
Point72 Asset Management
Connecticut
$32.2M +$35.9M +223,466 New
Franklin Resources
5
Franklin Resources
California
$32M +$2.14M +13,354 +6%
BlackRock
6
BlackRock
New York
$25.3M -$4.32M -26,915 -13%
Vanguard Group
7
Vanguard Group
Pennsylvania
$17.3M +$340K +2,115 +2%
State Street
8
State Street
Massachusetts
$5.66M +$357K +2,223 +6%
Millennium Management
9
Millennium Management
New York
$4.19M +$706K +4,394 +18%
TA
10
Teachers Advisors
New York
$4.17M +$33.1K +206 +0.7%
CS
11
Candriam SCA
Luxembourg
$3.87M -$1.15M -7,133 -21%
Northern Trust
12
Northern Trust
Illinois
$3.7M -$327K -2,035 -7%
Dimensional Fund Advisors
13
Dimensional Fund Advisors
Texas
$3.03M -$33.7K -210 -1%
IHM
14
Iguana Healthcare Management
New York
$2.88M -$1.07M -6,667 -25%
JP Morgan Chase
15
JP Morgan Chase
New York
$2.87M -$84.6K -527 -3%
Geode Capital Management
16
Geode Capital Management
Massachusetts
$2.69M +$166K +1,032 +6%
SSA
17
Schonfeld Strategic Advisors
New York
$2.4M
BBA
18
Baker Bros. Advisors
New York
$2.08M
Deutsche Bank
19
Deutsche Bank
Germany
$1.81M +$279K +1,740 +16%
Bank of New York Mellon
20
Bank of New York Mellon
New York
$1.57M -$7.71K -48 -0.4%
MOACM
21
Mutual of America Capital Management
New York
$1.49M +$11.4K +71 +0.7%
Charles Schwab
22
Charles Schwab
California
$1.44M +$106K +662 +7%
PAM
23
Panagora Asset Management
Massachusetts
$1.41M +$735K +4,575 +88%
AllianceBernstein
24
AllianceBernstein
Tennessee
$1.14M +$803K +5,000 +173%
OPPM
25
Opus Point Partners Management
New York
$960K

KPTI Hedge Fund Activity: Q4 2017 in Review

90 of the 4,409 institutional investors tracked by Wall St. Rank reported a position in Karyopharm Therapeutics (KPTI) for Q4 2017, worth a combined $298M — down 5.7% from $316M a quarter earlier.

Buyers outnumbered sellers: 18 funds opened new KPTI positions and 5 closed out — a net gain of 13 holders — while 32 added to existing stakes and 25 trimmed.

The largest buyer was Point72 Asset Management, opening a new position worth an estimated $35.9M. The largest seller was Tekla Capital Management, cutting an estimated $8.1M.

  • 90 institutional investors held Karyopharm Therapeutics (KPTI) as of Q4 2017, up from 77 in Q3 2017.
  • Funds reported $298M of Karyopharm Therapeutics stock for Q4 2017, down 5.7% quarter-over-quarter.
  • 18 funds opened new Karyopharm Therapeutics positions in Q4 2017 and 5 closed out, a net change of +13 holders.
  • The largest Karyopharm Therapeutics buyer in Q4 2017 was Point72 Asset Management, an estimated $35.9M added.
  • The largest Karyopharm Therapeutics seller in Q4 2017 was Tekla Capital Management, an estimated $8.1M sold.

Based on aggregated 13F filings for Q4 2017.