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Karyopharm Therapeutics
KPTI

Overview Fund Activity

77 hedge funds and large institutions have $316M invested in Karyopharm Therapeutics in 2017 Q3 according to their latest regulatory filings, with 8 funds opening new positions, 37 increasing their positions, 14 reducing their positions, and 4 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
77
Holders Change
+4
Holders Change %
+5.48%
% of All Funds
1.92%
Holding in Top 10
–
Holding in Top 10 Change
–
Holding in Top 10 Change %
–
% of All Funds
–
New
8
Increased
37
Reduced
14
Closed
4
Calls
$1.3M
Puts
$123K
Net Calls
+$1.18M
Net Calls Change
+$751K

Top Buyers

1
JPMorgan Chase & Co
JPMorgan Chase & Co
New York
+$2.95M
2
Wellington Management Group
Wellington Management Group
Massachusetts
+$2.47M
3
Millennium Management
Millennium Management
New York
+$1.67M
4
Vanguard Group
Vanguard Group
Pennsylvania
+$1.63M
5
IHM
Iguana Healthcare Management
New York
+$1.1M

Top Sellers

1
Fidelity Investments
Fidelity Investments
Massachusetts
-$3.48M
2
SSA
Schonfeld Strategic Advisors
New York
-$823K
3
Citadel Advisors
Citadel Advisors
Florida
-$452K
4
Barclays
Barclays
United Kingdom
-$325K
5
RJA
Raymond James & Associates
Florida
-$222K
Name Holding Trade Value Shares
Change 		Shares
Change %
Wellington Management Group
1
Wellington Management Group
Massachusetts
$69M +$2.47M +14,978 +4%
Fidelity Investments
2
Fidelity Investments
Massachusetts
$44M -$3.48M -21,133 -7%
PAI
3
Palo Alto Investors
California
$38.4M +$340K +2,067 +0.9%
Franklin Resources
4
Franklin Resources
California
$34.4M +$384K +2,329 +1%
BlackRock
5
BlackRock
New York
$33.4M +$910K +5,528 +3%
Vanguard Group
6
Vanguard Group
Pennsylvania
$19.4M +$1.63M +9,883 +9%
TCM
7
Tekla Capital Management
Massachusetts
$8.31M – – –
State Street
8
State Street
Massachusetts
$6.11M +$489K +2,968 +9%
CS
9
Candriam SCA
Luxembourg
$5.6M +$791K +4,800 +16%
TA
10
Teachers Advisors
New York
$4.74M +$1.65K +10 +0%
Northern Trust
11
Northern Trust
Illinois
$4.57M +$119K +724 +3%
IHM
12
Iguana Healthcare Management
New York
$4.39M +$1.1M +6,667 +33%
Millennium Management
13
Millennium Management
New York
$4.07M +$1.67M +10,118 +69%
Dimensional Fund Advisors
14
Dimensional Fund Advisors
Texas
$3.5M -$50.9K -309 -1%
JPMorgan Chase & Co
15
JPMorgan Chase & Co
New York
$3.34M +$2.95M +18,081 +754%
Geode Capital Management
16
Geode Capital Management
Massachusetts
$2.91M +$51.7K +314 +2%
SSA
17
Schonfeld Strategic Advisors
New York
$2.75M -$823K -5,000 -23%
BBA
18
Baker Bros. Advisors
New York
$2.38M – – –
Bank of New York Mellon
19
Bank of New York Mellon
New York
$1.8M +$12.5K +76 +0.7%
Deutsche Bank
20
Deutsche Bank
Germany
$1.78M -$90K -547 -5%
MOACM
21
Mutual of America Capital Management
New York
$1.7M – – –
Charles Schwab
22
Charles Schwab
California
$1.54M +$267K +1,621 +21%
NFA
23
Nationwide Fund Advisors
Ohio
$1.16M +$926K +5,624 +396%
OPPM
24
Opus Point Partners Management
New York
$1.1M – – –
TCIM
25
TIAA CREF Investment Management
New York
$996K -$140K -851 -12%
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