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Karyopharm Therapeutics

108 hedge funds and large institutions have $737M invested in Karyopharm Therapeutics in 2018 Q2 according to their latest regulatory filings, with 32 funds opening new positions, 43 increasing their positions, 21 reducing their positions, and 10 closing their positions.

New
Increased
Maintained
Reduced
Closed

220% more first-time investments, than exits

New positions opened: 32 | Existing positions closed: 10

105% more repeat investments, than reductions

Existing positions increased: 43 | Existing positions reduced: 21

78% more capital invested

Capital invested by funds: $415M → $737M (+$322M)

23% more funds holding

Funds holding: 88108 (+20)

8% more call options, than puts

Call options by funds: $616K | Put options by funds: $572K

0.65% more ownership

Funds ownership: 4.15%4.8% (+0.65%)

Holders
108
Holders Change
+20
Holders Change %
+22.73%
% of All Funds
2.47%
Holding in Top 10
2
Holding in Top 10 Change
+2
Holding in Top 10 Change %
% of All Funds
0.05%
New
32
Increased
43
Reduced
21
Closed
10
Calls
$616K
Puts
$572K
Net Calls
+$44K
Net Calls Change
+$98K
Name Holding Trade Value Shares
Change
Change in
Stake
Wellington Management Group
1
Wellington Management Group
Massachusetts
$140M +$24M +97,217 +21%
CCM
2
Consonance Capital Management
New York
$81M +$78.6M +317,805 New
PAI
3
Palo Alto Investors
California
$79.2M +$16.2M +65,556 +27%
BlackRock
4
BlackRock
New York
$68.9M +$21.4M +86,505 +47%
Vanguard Group
5
Vanguard Group
Pennsylvania
$42.4M +$9.19M +37,144 +29%
State Street
6
State Street
Massachusetts
$39.7M +$22.2M +89,918 +136%
Franklin Resources
7
Franklin Resources
California
$35.7M +$845K +3,418 +2%
Fidelity Investments
8
Fidelity Investments
Massachusetts
$26.2M -$24.6M -99,480 -49%
Point72 Asset Management
9
Point72 Asset Management
Connecticut
$24.5M -$8.51M -34,422 -26%
Millennium Management
10
Millennium Management
New York
$17.7M -$3.84M -15,520 -18%
Northern Trust
11
Northern Trust
Illinois
$10.2M +$3.38M +13,646 +52%
TCIM
12
TIAA CREF Investment Management
New York
$9.7M +$5.09M +20,574 +118%
EA
13
Emerald Advisers
Pennsylvania
$9.54M +$9.26M +37,421 New
Geode Capital Management
14
Geode Capital Management
Massachusetts
$8.76M +$3.2M +12,951 +60%
Goldman Sachs
15
Goldman Sachs
New York
$8.63M +$6.54M +26,430 +355%
Two Sigma Investments
16
Two Sigma Investments
New York
$8.58M +$6.31M +25,528 +314%
CS
17
Candriam SCA
Luxembourg
$8.36M +$4.49M +18,133 +124%
EMFAT
18
Emerald Mutual Fund Advisers Trust
Pennsylvania
$8.12M +$7.88M +31,846 New
PCA
19
Private Capital Advisors
Connecticut
$7.08M +$6.87M +27,793 New
SSA
20
Schonfeld Strategic Advisors
New York
$7.06M +$869K +3,514 +15%
Macquarie Group
21
Macquarie Group
Australia
$5.79M +$5.62M +22,707 New
TA
22
Teachers Advisors
New York
$5.65M -$1.68M -6,783 -23%
Deutsche Bank
23
Deutsche Bank
Germany
$5.62M +$2.32M +9,398 +74%
Dimensional Fund Advisors
24
Dimensional Fund Advisors
Texas
$5.24M -$82.4K -333 -2%
FCM
25
Frontier Capital Management
Massachusetts
$5.22M +$5.06M +20,469 New

KPTI Hedge Fund Activity: Q2 2018 in Review

108 of the 4,369 institutional investors tracked by Wall St. Rank reported a position in Karyopharm Therapeutics (KPTI) for Q2 2018, worth a combined $737M — up 78% from $415M a quarter earlier.

Buyers outnumbered sellers: 32 funds opened new KPTI positions and 10 closed out — a net gain of 22 holders — while 43 added to existing stakes and 21 trimmed.

The largest buyer was Consonance Capital Management, opening a new position worth an estimated $78.6M. The largest seller was Fidelity Investments, cutting an estimated $24.6M.

  • 108 institutional investors held Karyopharm Therapeutics (KPTI) as of Q2 2018, up from 88 in Q1 2018.
  • Funds reported $737M of Karyopharm Therapeutics stock for Q2 2018, up 78% quarter-over-quarter.
  • 32 funds opened new Karyopharm Therapeutics positions in Q2 2018 and 10 closed out, a net change of +22 holders.
  • The largest Karyopharm Therapeutics buyer in Q2 2018 was Consonance Capital Management, an estimated $78.6M added.
  • The largest Karyopharm Therapeutics seller in Q2 2018 was Fidelity Investments, an estimated $24.6M sold.

Based on aggregated 13F filings for Q2 2018.