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Karyopharm Therapeutics
KPTI

Overview Fund Activity

108 hedge funds and large institutions have $737M invested in Karyopharm Therapeutics in 2018 Q2 according to their latest regulatory filings, with 32 funds opening new positions, 43 increasing their positions, 21 reducing their positions, and 10 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
108
Holders Change
+20
Holders Change %
+22.73%
% of All Funds
2.48%
Holding in Top 10
2
Holding in Top 10 Change
+2
Holding in Top 10 Change %
%
% of All Funds
0.05%
New
32
Increased
43
Reduced
21
Closed
10
Calls
$616K
Puts
$572K
Net Calls
+$44K
Net Calls Change
+$98K

Top Buyers

1
CCM
Consonance Capital Management
New York
+$81M
2
Wellington Management Group
Wellington Management Group
Massachusetts
+$24.8M
3
State Street
State Street
Massachusetts
+$22.9M
4
BlackRock
BlackRock
New York
+$22M
5
PAI
Palo Alto Investors
California
+$16.7M

Top Sellers

1
Fidelity Investments
Fidelity Investments
Massachusetts
-$25.4M
2
Point72 Asset Management
Point72 Asset Management
Connecticut
-$8.77M
3
ACA
Avoro Capital Advisors
New York
-$7.52M
4
Millennium Management
Millennium Management
New York
-$3.96M
5
JPMorgan Chase & Co
JPMorgan Chase & Co
New York
-$2.85M
Name Holding Trade Value Shares
Change 		Shares
Change %
Wellington Management Group
1
Wellington Management Group
Massachusetts
$140M +$24.8M +97,217 +21%
CCM
2
Consonance Capital Management
New York
$81M +$81M +317,805 New
PAI
3
Palo Alto Investors
California
$79.2M +$16.7M +65,556 +27%
BlackRock
4
BlackRock
New York
$68.9M +$22M +86,505 +47%
Vanguard Group
5
Vanguard Group
Pennsylvania
$42.4M +$9.47M +37,144 +29%
State Street
6
State Street
Massachusetts
$39.7M +$22.9M +89,918 +136%
Franklin Resources
7
Franklin Resources
California
$35.7M +$871K +3,418 +2%
Fidelity Investments
8
Fidelity Investments
Massachusetts
$26.2M -$25.4M -99,480 -49%
Point72 Asset Management
9
Point72 Asset Management
Connecticut
$24.5M -$8.77M -34,422 -26%
Millennium Management
10
Millennium Management
New York
$17.7M -$3.96M -15,520 -18%
Northern Trust
11
Northern Trust
Illinois
$10.2M +$3.48M +13,646 +52%
TCIM
12
TIAA CREF Investment Management
New York
$9.7M +$5.24M +20,574 +118%
EA
13
Emerald Advisers
Pennsylvania
$9.54M +$9.54M +37,421 New
Geode Capital Management
14
Geode Capital Management
Massachusetts
$8.76M +$3.3M +12,951 +60%
Goldman Sachs
15
Goldman Sachs
New York
$8.63M +$6.74M +26,430 +355%
Two Sigma Investments
16
Two Sigma Investments
New York
$8.58M +$6.51M +25,528 +314%
CS
17
Candriam SCA
Luxembourg
$8.36M +$4.62M +18,133 +124%
EMFAT
18
Emerald Mutual Fund Advisers Trust
Pennsylvania
$8.12M +$8.12M +31,846 New
PCA
19
Private Capital Advisors
Connecticut
$7.08M +$7.08M +27,793 New
SSA
20
Schonfeld Strategic Advisors
New York
$7.06M +$896K +3,514 +15%
Macquarie Group
21
Macquarie Group
Australia
$5.79M +$5.79M +22,707 New
TA
22
Teachers Advisors
New York
$5.65M -$1.73M -6,783 -23%
Deutsche Bank
23
Deutsche Bank
Germany
$5.62M +$2.4M +9,398 +74%
Dimensional Fund Advisors
24
Dimensional Fund Advisors
Texas
$5.24M -$84.9K -333 -2%
FCM
25
Frontier Capital Management
Massachusetts
$5.22M +$5.22M +20,469 New
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