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Karyopharm Therapeutics

78 hedge funds and large institutions have $704M invested in Karyopharm Therapeutics in 2014 Q2 according to their latest regulatory filings, with 29 funds opening new positions, 30 increasing their positions, 18 reducing their positions, and 10 closing their positions.

New
Increased
Maintained
Reduced
Closed

190% more first-time investments, than exits

New positions opened: 29 | Existing positions closed: 10

126% more capital invested

Capital invested by funds: $311M → $704M (+$393M)

100% more funds holding in top 10

Funds holding in top 10: 12 (+1)

67% more repeat investments, than reductions

Existing positions increased: 30 | Existing positions reduced: 18

30% more funds holding

Funds holding: 6078 (+18)

Holders
78
Holders Change
+18
Holders Change %
+30%
% of All Funds
2.24%
Holding in Top 10
2
Holding in Top 10 Change
+1
Holding in Top 10 Change %
+100%
% of All Funds
0.06%
New
29
Increased
30
Reduced
18
Closed
10
Calls
Puts
Net Calls
Net Calls Change
Name Holding Trade Value Shares
Change
Change in
Stake
Franklin Resources
1
Franklin Resources
California
$198M +$69.3M +148,989 +111%
Fidelity Investments
2
Fidelity Investments
Massachusetts
$159M +$33.1M +71,209 +46%
FCMI
3
Foresite Capital Management I
California
$64.1M -$6.46M -13,889 -13%
BA
4
BlackRock Advisors
Delaware
$34.3M +$3.08M +6,620 +16%
PHS
5
PFM Health Sciences
California
$30.9M +$11M +23,550 +114%
AllianceBernstein
6
AllianceBernstein
Tennessee
$19.2M -$1.05M -2,262 -8%
CAM
7
Cormorant Asset Management
Massachusetts
$17.9M +$3.26M +7,000 +37%
Wellington Management Group
8
Wellington Management Group
Massachusetts
$15.7M -$1.38M -2,974 -12%
BFA
9
BlackRock Fund Advisors
California
$14.2M +$2.64M +5,669 +38%
Vanguard Group
10
Vanguard Group
Pennsylvania
$13.8M +$4.74M +10,187 +106%
SAM
11
Sectoral Asset Management
Quebec, Canada
$12.5M +$8.33M +17,903 New
BG
12
BlackRock Group
United Kingdom
$10.8M +$2.96M +6,366 +70%
State Street
13
State Street
Massachusetts
$7.87M +$1.87M +4,017 +55%
PC
14
PointState Capital
New York
$6.98M +$3.1M +6,667 +200%
VAM
15
Visium Asset Management
New York
$6.98M +$4.65M +10,000 New
BIT
16
BlackRock Institutional Trust
California
$6.21M +$1.63M +3,500 +65%
Lord, Abbett & Co
17
Lord, Abbett & Co
New Jersey
$5.68M +$3.79M +8,142 New
TG
18
TCW Group
California
$5.68M -$108K -231 -3%
BlackRock
19
BlackRock
New York
$5.04M +$899K +1,931 +37%
BBA
20
Baker Bros. Advisors
New York
$4.38M +$1.09M +2,333 +59%
GC
21
Guggenheim Capital
Illinois
$4.19M +$519K +1,116 +23%
Northern Trust
22
Northern Trust
Illinois
$4.16M -$202K -434 -7%
EAM
23
EverPoint Asset Management
Connecticut
$3.72M +$2.48M +5,333 New
Citadel Advisors
24
Citadel Advisors
Florida
$3.67M +$2.45M +5,260 New
DCM
25
Driehaus Capital Management
Illinois
$3.58M +$260K +559 +12%

KPTI Hedge Fund Activity: Q2 2014 in Review

78 of the 3,480 institutional investors tracked by Wall St. Rank reported a position in Karyopharm Therapeutics (KPTI) for Q2 2014, worth a combined $704M — up 126% from $311M a quarter earlier.

Buyers outnumbered sellers: 29 funds opened new KPTI positions and 10 closed out — a net gain of 19 holders — while 30 added to existing stakes and 18 trimmed.

The largest buyer was Franklin Resources, adding an estimated $69.3M. The largest seller was Foresite Capital Management I, cutting an estimated $6.46M.

  • 78 institutional investors held Karyopharm Therapeutics (KPTI) as of Q2 2014, up from 60 in Q1 2014.
  • Funds reported $704M of Karyopharm Therapeutics stock for Q2 2014, up 126% quarter-over-quarter.
  • 29 funds opened new Karyopharm Therapeutics positions in Q2 2014 and 10 closed out, a net change of +19 holders.
  • The largest Karyopharm Therapeutics buyer in Q2 2014 was Franklin Resources, an estimated $69.3M added.
  • The largest Karyopharm Therapeutics seller in Q2 2014 was Foresite Capital Management I, an estimated $6.46M sold.

Based on aggregated 13F filings for Q2 2014.