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Karyopharm Therapeutics
KPTI

Overview Fund Activity

134 hedge funds and large institutions have $334M invested in Karyopharm Therapeutics in 2021 Q3 according to their latest regulatory filings, with 14 funds opening new positions, 58 increasing their positions, 34 reducing their positions, and 33 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
134
Holders Change
-19
Holders Change %
-12.42%
% of All Funds
2.35%
Holding in Top 10
1
Holding in Top 10 Change
–
Holding in Top 10 Change %
–
% of All Funds
0.02%
New
14
Increased
58
Reduced
34
Closed
33
Calls
$2.28M
Puts
$8.13M
Net Calls
-$5.85M
Net Calls Change
+$3.66M

Top Buyers

1
State Street
State Street
Massachusetts
$46.7M
2
Renaissance Technologies
Renaissance Technologies
New York
$2.88M
3
UBS Group
UBS Group
Switzerland
$3.54M
4
Two Sigma Investments
Two Sigma Investments
New York
$6.38M
5
Morgan Stanley
Morgan Stanley
New York
$11M

Top Sellers

1
HRCM
Hood River Capital Management
Florida
$0
2
GIM
Granahan Investment Management
Massachusetts
$0
3
Wellington Management Group
Wellington Management Group
Massachusetts
$0
4
JGC
J. Goldman & Co
New York
$336K
5
AAM
AMI Asset Management
California
$0
Name Holding Trade Value Shares
Change 		Shares
Change %
BlackRock
1
BlackRock
New York
$51.2M +$52.7K +604 +0.1%
State Street
2
State Street
Massachusetts
$46.7M +$12.8M +146,897 +38%
PAI
3
Palo Alto Investors
California
$31.3M – – –
Vanguard Group
4
Vanguard Group
Pennsylvania
$21.2M +$171K +1,958 +0.8%
RCMNY
5
Rubric Capital Management (New York)
New York
$19.6M -$5.11M -58,496 -21%
DMPV
6
Delphi Management Partners VIII
California
$13.2M – – –
Alkeon Capital Management
7
Alkeon Capital Management
New York
$11.4M -$4.08M -46,772 -26%
Morgan Stanley
8
Morgan Stanley
New York
$11M +$1.46M +16,684 +15%
LOAMS
9
Lombard Odier Asset Management (Switzerland)
Switzerland
$8.83M +$823K +9,429 +10%
Geode Capital Management
10
Geode Capital Management
Massachusetts
$8.19M +$1.23M +14,125 +18%
RHJA
11
Rice Hall James & Associates
California
$8.16M -$43.9K -503 -0.5%
CWG
12
C WorldWide Group
Denmark
$6.98M – – –
Nuveen Asset Management
13
Nuveen Asset Management
Illinois
$6.79M -$103K -1,127 -1%
FCM
14
Frontier Capital Management
Massachusetts
$6.42M -$2.25M -25,768 -26%
Two Sigma Investments
15
Two Sigma Investments
New York
$6.38M +$1.46M +16,704 +30%
Two Sigma Advisers
16
Two Sigma Advisers
New York
$6.3M +$580K +6,640 +10%
Goldman Sachs
17
Goldman Sachs
New York
$5.74M -$118K -1,356 -2%
Northern Trust
18
Northern Trust
Illinois
$4.46M -$106K -1,215 -2%
CS
19
Candriam SCA
Luxembourg
$4.18M – – –
UBS Group
20
UBS Group
Switzerland
$3.54M +$1.83M +20,997 +107%
Susquehanna International Group
21
Susquehanna International Group
Pennsylvania
$3.15M +$1.26M +14,486 +67%
Renaissance Technologies
22
Renaissance Technologies
New York
$2.88M +$2.78M +31,796 +2,583%
BNP Paribas Financial Markets
23
BNP Paribas Financial Markets
France
$2.73M +$439K +5,034 +19%
JPMorgan Chase & Co
24
JPMorgan Chase & Co
New York
$2.71M -$106K -1,220 -4%
HWAM
25
Hennion & Walsh Asset Management
New Jersey
$2.37M +$184K +2,112 +8%
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