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Karyopharm Therapeutics

85 hedge funds and large institutions have $285M invested in Karyopharm Therapeutics in 2015 Q4 according to their latest regulatory filings, with 10 funds opening new positions, 37 increasing their positions, 22 reducing their positions, and 14 closing their positions.

New
Increased
Maintained
Reduced
Closed

68% more repeat investments, than reductions

Existing positions increased: 37 | Existing positions reduced: 22

25% more call options, than puts

Call options by funds: $2.38M | Put options by funds: $1.91M

15% more capital invested

Capital invested by funds: $248M → $285M (+$37.2M)

4% less funds holding

Funds holding: 8985 (-4)

29% less first-time investments, than exits

New positions opened: 10 | Existing positions closed: 14

Holders
85
Holders Change
-4
Holders Change %
-4.49%
% of All Funds
2.23%
Holding in Top 10
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
New
10
Increased
37
Reduced
22
Closed
14
Calls
$2.38M
Puts
$1.91M
Net Calls
+$474K
Net Calls Change
-$7.02M
Name Holding Trade Value Shares
Change
Change in
Stake
Fidelity Investments
1
Fidelity Investments
Massachusetts
$71M +$45.7K +211 +0.1%
Franklin Resources
2
Franklin Resources
California
$68.5M -$6.43M -29,717 -8%
PAI
3
Palo Alto Investors
California
$41.2M +$388K +1,794 +0.9%
Millennium Management
4
Millennium Management
New York
$17.1M +$3.88M +17,908 +26%
BFA
5
BlackRock Fund Advisors
California
$13.8M -$1.1M -5,058 -7%
Vanguard Group
6
Vanguard Group
Pennsylvania
$9.3M +$54.8K +253 +0.5%
BIT
7
BlackRock Institutional Trust
California
$6.89M +$144K +666 +2%
TCM
8
Tekla Capital Management
Massachusetts
$6.63M -$6.04M -27,903 -46%
State Street
9
State Street
Massachusetts
$4.52M +$507K +2,342 +11%
Northern Trust
10
Northern Trust
Illinois
$3.31M +$121K +560 +3%
JP Morgan Chase
11
JP Morgan Chase
New York
$2.88M +$1.97M +9,119 +170%
BBA
12
Baker Bros. Advisors
New York
$2.88M
CS
13
Candriam SCA
Luxembourg
$2.53M +$433K +2,000 +19%
Wellington Management Group
14
Wellington Management Group
Massachusetts
$2.3M +$49.6K +229 +2%
FLAM
15
First Light Asset Management
Minnesota
$2.02M -$28.1K -130 -1%
Geode Capital Management
16
Geode Capital Management
Massachusetts
$1.84M +$34.2K +158 +2%
Wells Fargo
17
Wells Fargo
California
$1.79M +$1.79M +8,263 +1,133%
GC
18
Guggenheim Capital
Illinois
$1.53M -$250K -1,156 -13%
SIP
19
Stoneridge Investment Partners
Pennsylvania
$1.42M +$30.7K +142 +2%
Bank of New York Mellon
20
Bank of New York Mellon
New York
$1.38M -$3.03K -14 -0.2%
Deutsche Bank
21
Deutsche Bank
Germany
$1.38M +$246K +1,138 +20%
MOACM
22
Mutual of America Capital Management
New York
$1.17M +$478K +2,209 +60%
New York State Common Retirement Fund
23
New York State Common Retirement Fund
New York
$1.08M
BIM
24
BlackRock Investment Management
Delaware
$1.06M +$9.53K +44 +0.8%
ARTA
25
A.R.T. Advisors
New York
$1.02M -$854K -3,944 -43%

KPTI Hedge Fund Activity: Q4 2015 in Review

85 of the 3,812 institutional investors tracked by Wall St. Rank reported a position in Karyopharm Therapeutics (KPTI) for Q4 2015, worth a combined $285M — up 15% from $248M a quarter earlier.

Sellers outnumbered buyers: 14 funds closed out of KPTI and 10 opened new positions — a net loss of 4 holders — while 22 trimmed existing stakes and 37 added.

The largest buyer was Millennium Management, adding an estimated $3.88M. The largest seller was Citadel Advisors, cutting an estimated $8.02M.

  • 85 institutional investors held Karyopharm Therapeutics (KPTI) as of Q4 2015, down from 89 in Q3 2015.
  • Funds reported $285M of Karyopharm Therapeutics stock for Q4 2015, up 15% quarter-over-quarter.
  • 10 funds opened new Karyopharm Therapeutics positions in Q4 2015 and 14 closed out, a net change of -4 holders.
  • The largest Karyopharm Therapeutics buyer in Q4 2015 was Millennium Management, an estimated $3.88M added.
  • The largest Karyopharm Therapeutics seller in Q4 2015 was Citadel Advisors, an estimated $8.02M sold.

Based on aggregated 13F filings for Q4 2015.