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Karyopharm Therapeutics
KPTI

Overview Fund Activity

85 hedge funds and large institutions have $285M invested in Karyopharm Therapeutics in 2015 Q4 according to their latest regulatory filings, with 10 funds opening new positions, 37 increasing their positions, 22 reducing their positions, and 14 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
85
Holders Change
-4
Holders Change %
-4.49%
% of All Funds
2.23%
Holding in Top 10
–
Holding in Top 10 Change
–
Holding in Top 10 Change %
–
% of All Funds
–
New
10
Increased
37
Reduced
22
Closed
14
Calls
$2.38M
Puts
$1.91M
Net Calls
+$474K
Net Calls Change
-$7.02M

Top Buyers

1
Millennium Management
Millennium Management
New York
$17.2M
2
JPMorgan Chase & Co
JPMorgan Chase & Co
New York
$2.88M
3
Wells Fargo
Wells Fargo
California
$1.79M
4
CS
Credit Suisse
Switzerland
$630K
5
OPPM
Opus Point Partners Management
New York
$795K

Top Sellers

1
SAM
Sectoral Asset Management
Quebec, Canada
$0
2
Citadel Advisors
Citadel Advisors
Florida
$303K
3
Franklin Resources
Franklin Resources
California
$68.5M
4
TCM
Tekla Capital Management
Massachusetts
$6.63M
5
CAM
Cormorant Asset Management
Massachusetts
$0
Name Holding Trade Value Shares
Change 		Shares
Change %
Fidelity Investments
1
Fidelity Investments
Massachusetts
$71M +$41.9K +211 +0.1%
Franklin Resources
2
Franklin Resources
California
$68.5M -$5.91M -29,717 -8%
PAI
3
Palo Alto Investors
California
$41.2M +$357K +1,794 +0.9%
Millennium Management
4
Millennium Management
New York
$17.2M +$3.56M +17,908 +26%
BFA
5
BlackRock Fund Advisors
California
$13.8M -$1.01M -5,058 -7%
Vanguard Group
6
Vanguard Group
Pennsylvania
$9.3M +$50.3K +253 +0.5%
BIT
7
BlackRock Institutional Trust
California
$6.89M +$132K +666 +2%
TCM
8
Tekla Capital Management
Massachusetts
$6.63M -$5.55M -27,903 -46%
State Street
9
State Street
Massachusetts
$4.52M +$466K +2,342 +11%
Northern Trust
10
Northern Trust
Illinois
$3.31M +$111K +560 +3%
JPMorgan Chase & Co
11
JPMorgan Chase & Co
New York
$2.88M +$1.81M +9,119 +170%
BBA
12
Baker Bros. Advisors
New York
$2.88M – – –
CS
13
Candriam SCA
Luxembourg
$2.53M +$397K +2,000 +19%
Wellington Management Group
14
Wellington Management Group
Massachusetts
$2.3M +$45.5K +229 +2%
FLAM
15
First Light Asset Management
Minnesota
$2.02M -$25.8K -130 -1%
Geode Capital Management
16
Geode Capital Management
Massachusetts
$1.84M +$31.4K +158 +2%
Wells Fargo
17
Wells Fargo
California
$1.79M +$1.64M +8,263 +1,133%
GC
18
Guggenheim Capital
Illinois
$1.53M -$230K -1,156 -13%
SIP
19
Stoneridge Investment Partners
Pennsylvania
$1.42M +$28.2K +142 +2%
Bank of New York Mellon
20
Bank of New York Mellon
New York
$1.38M -$2.78K -14 -0.2%
Deutsche Bank
21
Deutsche Bank
Germany
$1.38M +$226K +1,138 +20%
MOACM
22
Mutual of America Capital Management
New York
$1.17M +$439K +2,209 +60%
New York State Common Retirement Fund
23
New York State Common Retirement Fund
New York
$1.08M – – –
BIM
24
BlackRock Investment Management
Delaware
$1.06M +$8.74K +44 +0.8%
ARTA
25
A.R.T. Advisors
New York
$1.02M -$783K -3,944 -43%
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