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Karyopharm Therapeutics
KPTI

Overview Fund Activity

137 hedge funds and large institutions have $145M invested in Karyopharm Therapeutics in 2023 Q2 according to their latest regulatory filings, with 30 funds opening new positions, 43 increasing their positions, 41 reducing their positions, and 22 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
137
Holders Change
+8
Holders Change %
+6.2%
% of All Funds
2.16%
Holding in Top 10
–
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-100%
% of All Funds
–
New
30
Increased
43
Reduced
41
Closed
22
Calls
$613K
Puts
$242K
Net Calls
+$371K
Net Calls Change
-$148K

Top Buyers

1
BlackRock
BlackRock
New York
$20.7M
2
ECM
ExodusPoint Capital Management
New York
$4.27M
3
ACM
AIGH Capital Management
Maryland
$3.17M
4
Vanguard Group
Vanguard Group
Pennsylvania
$15.5M
5
Millennium Management
Millennium Management
New York
$2.06M

Top Sellers

1
State Street
State Street
Massachusetts
$3.96M
2
RCMNY
Rubric Capital Management (New York)
New York
$1.65M
3
Rafferty Asset Management
Rafferty Asset Management
New York
$0
4
Bank of America
Bank of America
North Carolina
$602K
5
Barclays
Barclays
United Kingdom
$1.98M
Name Holding Trade Value Shares
Change 		Shares
Change %
BlackRock
1
BlackRock
New York
$20.7M +$4.41M +164,339 +27%
Vanguard Group
2
Vanguard Group
Pennsylvania
$15.5M +$2.11M +78,686 +16%
APM
3
Avidity Partners Management
Texas
$15M -$2.26M -84,254 -13%
PAI
4
Palo Alto Investors
California
$10.2M – – –
Citadel Advisors
5
Citadel Advisors
Florida
$5.64M -$810K -30,185 -13%
Marshall Wace
6
Marshall Wace
United Kingdom
$4.37M +$822K +30,606 +23%
ECM
7
ExodusPoint Capital Management
New York
$4.27M +$4.27M +158,830 New
State Street
8
State Street
Massachusetts
$3.96M -$14.3M -530,908 -78%
Geode Capital Management
9
Geode Capital Management
Massachusetts
$3.83M +$654K +24,357 +21%
OM
10
Opaleye Management
Massachusetts
$3.2M -$1.84M -68,387 -36%
ACM
11
AIGH Capital Management
Maryland
$3.17M +$3.17M +118,232 New
Goldman Sachs
12
Goldman Sachs
New York
$2.9M +$272K +10,125 +10%
Deutsche Bank
13
Deutsche Bank
Germany
$2.85M -$92.6K -3,450 -3%
CWG
14
C WorldWide Group
Denmark
$2.69M – – –
CS
15
Candriam SCA
Luxembourg
$2.57M -$178K -6,622 -6%
Millennium Management
16
Millennium Management
New York
$2.06M +$2.04M +75,831 +8,260%
TC
17
Tejara Capital
United Kingdom
$2.05M +$1.15M +42,829 +128%
Barclays
18
Barclays
United Kingdom
$1.98M -$3.12M -116,069 -61%
Northern Trust
19
Northern Trust
Illinois
$1.91M +$437K +16,290 +30%
RCMNY
20
Rubric Capital Management (New York)
New York
$1.65M -$6.3M -234,790 -79%
AA
21
AlphaCentric Advisors
Puerto Rico
$1.45M +$1.02M +38,000 +238%
ACM
22
Altium Capital Management
New York
$1.32M +$419K +15,614 +46%
Qube Research & Technologies (QRT)
23
Qube Research & Technologies (QRT)
United Kingdom
$1.26M +$1.26M +46,871 New
Jacobs Levy Equity Management
24
Jacobs Levy Equity Management
New Jersey
$1.21M -$713K -26,548 -37%
Renaissance Technologies
25
Renaissance Technologies
New York
$1.2M -$122K -4,554 -9%
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