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Karyopharm Therapeutics

171 hedge funds and large institutions have $637M invested in Karyopharm Therapeutics in 2021 Q1 according to their latest regulatory filings, with 28 funds opening new positions, 57 increasing their positions, 57 reducing their positions, and 24 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
171
Holders Change
+3
Holders Change %
+1.79%
% of All Funds
3.01%
Holding in Top 10
1
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-50%
% of All Funds
0.02%
New
28
Increased
57
Reduced
57
Closed
24
Calls
$2.61M
Puts
$3.95M
Net Calls
-$1.34M
Net Calls Change
-$4.58M
Name Holding Trade Value Shares
Change
Shares
Change %
BlackRock
1
BlackRock
New York
$81.5M +$2.89M +18,310 +4%
PAI
2
Palo Alto Investors
California
$56.4M +$1.01M +6,400 +2%
State Street
3
State Street
Massachusetts
$56.1M -$79.8K -506 -0.1%
Vanguard Group
4
Vanguard Group
Pennsylvania
$37.4M +$800K +5,070 +2%
Alkeon Capital Management
5
Alkeon Capital Management
New York
$28.1M +$18.8K +119 +0.1%
DMPV
6
Delphi Management Partners VIII
California
$23.8M
Wellington Management Group
7
Wellington Management Group
Massachusetts
$20.2M -$2.75M -17,430 -12%
Morgan Stanley
8
Morgan Stanley
New York
$17.9M +$10.1M +63,704 +129%
RHJA
9
Rice Hall James & Associates
California
$16.4M +$111K +703 +0.7%
Two Sigma Investments
10
Two Sigma Investments
New York
$15.7M +$15.3M +96,828 +3,612%
Adage Capital Partners
11
Adage Capital Partners
Massachusetts
$14.2M -$11.7M -74,346 -45%
CS
12
Candriam SCA
Luxembourg
$14.1M -$223 -1 -0%
JGC
13
J. Goldman & Co
New York
$14M +$11.2M +71,291 +409%
FCM
14
Frontier Capital Management
Massachusetts
$12.9M -$20.1M -127,063 -61%
Goldman Sachs
15
Goldman Sachs
New York
$12.8M +$1.65M +10,481 +15%
CWG
16
C WorldWide Group
Denmark
$12.6M +$6.31M +40,000 +100%
Geode Capital Management
17
Geode Capital Management
Massachusetts
$12.1M +$1.12M +7,125 +10%
LCM
18
Laurion Capital Management
New York
$10.3M
Nuveen Asset Management
19
Nuveen Asset Management
Illinois
$9.78M -$1.03M -6,535 -10%
Two Sigma Advisers
20
Two Sigma Advisers
New York
$9.58M +$4.24M +26,887 +80%
HRCM
21
Hood River Capital Management
Florida
$8.93M -$874K -5,537 -9%
LOAMS
22
Lombard Odier Asset Management (Switzerland)
Switzerland
$8.73M +$8.73M +55,312 New
CLOS
23
Compagnie Lombard Odier SCmA
Switzerland
$8.73M +$8.73M +55,312 New
Citadel Advisors
24
Citadel Advisors
Florida
$8.65M +$5.74M +36,362 +197%
Northern Trust
25
Northern Trust
Illinois
$7.84M -$377K -2,388 -5%