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Karyopharm Therapeutics
KPTI

Overview Fund Activity

155 hedge funds and large institutions have $1.32B invested in Karyopharm Therapeutics in 2020 Q2 according to their latest regulatory filings, with 44 funds opening new positions, 65 increasing their positions, 33 reducing their positions, and 23 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
155
Holders Change
+19
Holders Change %
+13.97%
% of All Funds
3.19%
Holding in Top 10
4
Holding in Top 10 Change
-5
Holding in Top 10 Change %
-55.56%
% of All Funds
0.08%
New
44
Increased
65
Reduced
33
Closed
23
Calls
$14.8M
Puts
$6.38M
Net Calls
+$8.46M
Net Calls Change
+$7.98M

Top Buyers

1
State Street
State Street
Massachusetts
+$25.6M
2
BlackRock
BlackRock
New York
+$20.1M
3
Goldman Sachs
Goldman Sachs
New York
+$19.7M
4
FCM
Frontier Capital Management
Massachusetts
+$18M
5
D.E. Shaw & Co
D.E. Shaw & Co
New York
+$10.8M

Top Sellers

1
Janus Henderson Group
Janus Henderson Group
United Kingdom
-$62.5M
2
Citadel Advisors
Citadel Advisors
Florida
-$25.9M
3
CCM
Consonance Capital Management
New York
-$13M
4
CS
Candriam SCA
Luxembourg
-$11.1M
5
Adage Capital Partners
Adage Capital Partners
Massachusetts
-$8.99M
Name Holding Trade Value Shares
Change 		Shares
Change %
ACA
1
Avoro Capital Advisors
New York
$133M – – –
CCM
2
Consonance Capital Management
New York
$123M -$13M -45,926 -10%
BlackRock
3
BlackRock
New York
$121M +$20.1M +70,844 +20%
State Street
4
State Street
Massachusetts
$87.1M +$25.6M +90,097 +42%
PAI
5
Palo Alto Investors
California
$79.9M -$1.52M -5,363 -2%
Vanguard Group
6
Vanguard Group
Pennsylvania
$67.5M +$5.98M +21,036 +10%
Adage Capital Partners
7
Adage Capital Partners
Massachusetts
$61.5M -$8.99M -31,652 -13%
D.E. Shaw & Co
8
D.E. Shaw & Co
New York
$56.3M +$10.8M +38,082 +24%
FCM
9
Frontier Capital Management
Massachusetts
$52.9M +$18M +63,404 +52%
Alkeon Capital Management
10
Alkeon Capital Management
New York
$39.1M -$1.89M -6,667 -5%
Goldman Sachs
11
Goldman Sachs
New York
$37.9M +$19.7M +69,389 +109%
T. Rowe Price Associates
12
T. Rowe Price Associates
Maryland
$37.2M +$10.7M +37,789 +41%
Wellington Management Group
13
Wellington Management Group
Massachusetts
$28.5M +$1.97M +6,924 +7%
FCM
14
Farallon Capital Management
California
$25.3M – – –
EA
15
Emerald Advisers
Pennsylvania
$23.6M +$3.76M +13,244 +19%
EMFAT
16
Emerald Mutual Fund Advisers Trust
Pennsylvania
$19.6M +$3.24M +11,415 +20%
Geode Capital Management
17
Geode Capital Management
Massachusetts
$19.6M +$1.88M +6,617 +11%
HRCM
18
Hood River Capital Management
Florida
$19.1M +$2.26M +7,939 +13%
Two Sigma Advisers
19
Two Sigma Advisers
New York
$17.1M +$3.25M +11,426 +23%
Northern Trust
20
Northern Trust
Illinois
$17.1M +$2.6M +9,151 +18%
Dimensional Fund Advisors
21
Dimensional Fund Advisors
Texas
$14.8M -$5.84M -20,550 -28%
RHJA
22
Rice Hall James & Associates
California
$14.4M +$3.13M +11,005 +28%
Fidelity Investments
23
Fidelity Investments
Massachusetts
$12.8M -$1.78M -6,260 -12%
FFM
24
Fairmount Funds Management
Pennsylvania
$12.4M +$1.7M +6,000 +16%
Susquehanna International Group
25
Susquehanna International Group
Pennsylvania
$10.5M +$8.42M +29,628 +404%
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