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Karyopharm Therapeutics

155 hedge funds and large institutions have $1.32B invested in Karyopharm Therapeutics in 2020 Q2 according to their latest regulatory filings, with 44 funds opening new positions, 65 increasing their positions, 33 reducing their positions, and 23 closing their positions.

New
Increased
Maintained
Reduced
Closed

133% more call options, than puts

Call options by funds: $14.8M | Put options by funds: $6.38M

97% more repeat investments, than reductions

Existing positions increased: 65 | Existing positions reduced: 33

91% more first-time investments, than exits

New positions opened: 44 | Existing positions closed: 23

14% more funds holding

Funds holding: 136155 (+19)

1% more capital invested

Capital invested by funds: $1.31B → $1.32B (+$13.4M)

0.04% more ownership

Funds ownership: 6.31%6.36% (+0.04%)

56% less funds holding in top 10

Funds holding in top 10: 94 (-5)

Holders
155
Holders Change
+19
Holders Change %
+13.97%
% of All Funds
3.18%
Holding in Top 10
4
Holding in Top 10 Change
-5
Holding in Top 10 Change %
-55.56%
% of All Funds
0.08%
New
44
Increased
65
Reduced
33
Closed
23
Calls
$14.8M
Puts
$6.38M
Net Calls
+$8.46M
Net Calls Change
+$7.97M
Name Holding Trade Value Shares
Change
Change in
Stake
ACA
1
Avoro Capital Advisors
New York
$133M
CCM
2
Consonance Capital Management
New York
$123M -$13.6M -45,926 -10%
BlackRock
3
BlackRock
New York
$121M +$21M +70,844 +20%
State Street
4
State Street
Massachusetts
$87.1M +$26.6M +90,097 +42%
PAI
5
Palo Alto Investors
California
$79.9M -$1.59M -5,363 -2%
Vanguard Group
6
Vanguard Group
Pennsylvania
$67.5M +$6.22M +21,036 +10%
Adage Capital Partners
7
Adage Capital Partners
Massachusetts
$61.5M -$9.36M -31,652 -13%
D.E. Shaw & Co
8
D.E. Shaw & Co
New York
$56.3M +$11.3M +38,082 +24%
FCM
9
Frontier Capital Management
Massachusetts
$52.9M +$18.8M +63,404 +52%
Alkeon Capital Management
10
Alkeon Capital Management
New York
$39.1M -$1.97M -6,667 -5%
Goldman Sachs
11
Goldman Sachs
New York
$37.9M +$20.5M +69,389 +109%
T. Rowe Price Associates
12
T. Rowe Price Associates
Maryland
$37.2M +$11.2M +37,789 +41%
Wellington Management Group
13
Wellington Management Group
Massachusetts
$28.5M +$2.05M +6,924 +7%
FCM
14
Farallon Capital Management
California
$25.3M
EA
15
Emerald Advisers
Pennsylvania
$23.6M +$3.92M +13,244 +19%
EMFAT
16
Emerald Mutual Fund Advisers Trust
Pennsylvania
$19.6M +$3.38M +11,415 +20%
Geode Capital Management
17
Geode Capital Management
Massachusetts
$19.6M +$1.96M +6,617 +11%
HRCM
18
Hood River Capital Management
Florida
$19.1M +$2.35M +7,939 +13%
Two Sigma Advisers
19
Two Sigma Advisers
New York
$17.1M +$3.38M +11,426 +23%
Northern Trust
20
Northern Trust
Illinois
$17.1M +$2.71M +9,151 +18%
Dimensional Fund Advisors
21
Dimensional Fund Advisors
Texas
$14.8M -$6.08M -20,550 -28%
RHJA
22
Rice Hall James & Associates
California
$14.4M +$3.25M +11,005 +28%
Fidelity Investments
23
Fidelity Investments
Massachusetts
$12.8M -$1.85M -6,260 -12%
FFM
24
Fairmount Funds Management
Pennsylvania
$12.4M +$1.77M +6,000 +16%
Susquehanna International Group
25
Susquehanna International Group
Pennsylvania
$10.5M +$8.76M +29,628 +404%

KPTI Hedge Fund Activity: Q2 2020 in Review

155 of the 4,878 institutional investors tracked by Wall St. Rank reported a position in Karyopharm Therapeutics (KPTI) for Q2 2020, worth a combined $1.32B — up 1% from $1.31B a quarter earlier.

Buyers outnumbered sellers: 44 funds opened new KPTI positions and 23 closed out — a net gain of 21 holders — while 65 added to existing stakes and 33 trimmed.

The largest buyer was State Street, adding an estimated $26.6M. The largest seller was Janus Henderson Group, exiting entirely with an estimated $62.5M sold.

  • 155 institutional investors held Karyopharm Therapeutics (KPTI) as of Q2 2020, up from 136 in Q1 2020.
  • Funds reported $1.32B of Karyopharm Therapeutics stock for Q2 2020, up 1% quarter-over-quarter.
  • 44 funds opened new Karyopharm Therapeutics positions in Q2 2020 and 23 closed out, a net change of +21 holders.
  • The largest Karyopharm Therapeutics buyer in Q2 2020 was State Street, an estimated $26.6M added.
  • The largest Karyopharm Therapeutics seller in Q2 2020 was Janus Henderson Group, an estimated $62.5M sold.

Based on aggregated 13F filings for Q2 2020.