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Karyopharm Therapeutics

80 hedge funds and large institutions have $345M invested in Karyopharm Therapeutics in 2017 Q1 according to their latest regulatory filings, with 13 funds opening new positions, 31 increasing their positions, 22 reducing their positions, and 13 closing their positions.

New
Increased
Maintained
Reduced
Closed

158% more call options, than puts

Call options by funds: $2.04M | Put options by funds: $790K

44% more capital invested

Capital invested by funds: $239M → $345M (+$105M)

41% more repeat investments, than reductions

Existing positions increased: 31 | Existing positions reduced: 22

0.15% more ownership

Funds ownership: 4.12%4.27% (+0.15%)

0% more first-time investments, than exits

New positions opened: 13 | Existing positions closed: 13

7% less funds holding

Funds holding: 8680 (-6)

Holders
80
Holders Change
-6
Holders Change %
-6.98%
% of All Funds
1.99%
Holding in Top 10
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
New
13
Increased
31
Reduced
22
Closed
13
Calls
$2.04M
Puts
$790K
Net Calls
+$1.25M
Net Calls Change
+$280K
Name Holding Trade Value Shares
Change
Change in
Stake
Wellington Management Group
1
Wellington Management Group
Massachusetts
$74.2M +$579K +3,609 +0.9%
Fidelity Investments
2
Fidelity Investments
Massachusetts
$55.5M -$4.34M -27,020 -9%
PAI
3
Palo Alto Investors
California
$43.7M +$2.21M +13,738 +6%
Franklin Resources
4
Franklin Resources
California
$40.4M -$887K -5,528 -3%
BlackRock
5
BlackRock
New York
$32.2M +$26.8M +166,870 +60,242%
Vanguard Group
6
Vanguard Group
Pennsylvania
$15.9M +$1.18M +7,340 +10%
TCM
7
Tekla Capital Management
Massachusetts
$7.77M +$1.12M +6,993 +21%
JP Morgan Chase
8
JP Morgan Chase
New York
$6.66M +$1.14M +7,082 +26%
State Street
9
State Street
Massachusetts
$5.97M +$628K +3,912 +14%
TA
10
Teachers Advisors
New York
$5.4M +$4.06M +25,276 +915%
SSA
11
Schonfeld Strategic Advisors
New York
$4.37M +$3.64M +22,667 New
Northern Trust
12
Northern Trust
Illinois
$3.81M +$70.6K +440 +2%
Dimensional Fund Advisors
13
Dimensional Fund Advisors
Texas
$3.54M +$160K +994 +6%
IHM
14
Iguana Healthcare Management
New York
$3.53M +$2.94M +18,333 New
EI
15
EAM Investors
California
$3.46M +$2.89M +17,974 New
Millennium Management
16
Millennium Management
New York
$3.32M -$4.84M -30,177 -64%
BBA
17
Baker Bros. Advisors
New York
$2.79M
Bank of New York Mellon
18
Bank of New York Mellon
New York
$2.33M +$742K +4,621 +62%
CS
19
Candriam SCA
Luxembourg
$2.21M -$2.33M -14,533 -56%
Geode Capital Management
20
Geode Capital Management
Massachusetts
$2.17M +$131K +818 +8%
MOACM
21
Mutual of America Capital Management
New York
$2.05M +$779K +4,852 +84%
D.E. Shaw & Co
22
D.E. Shaw & Co
New York
$1.87M +$1.12M +6,967 +253%
Deutsche Bank
23
Deutsche Bank
Germany
$1.72M +$164K +1,020 +13%
Ameriprise
24
Ameriprise
Minnesota
$1.13M +$940K +5,859 New
Charles Schwab
25
Charles Schwab
California
$1.11M +$40.3K +251 +5%

KPTI Hedge Fund Activity: Q1 2017 in Review

80 of the 4,018 institutional investors tracked by Wall St. Rank reported a position in Karyopharm Therapeutics (KPTI) for Q1 2017, worth a combined $345M — up 44% from $239M a quarter earlier.

Fund positioning in KPTI was balanced in Q1 2017: 13 funds opened new positions, 13 closed out, 31 added to existing stakes and 22 trimmed.

The largest buyer was BlackRock, adding an estimated $26.8M. The largest seller was Millennium Management, cutting an estimated $4.84M.

  • 80 institutional investors held Karyopharm Therapeutics (KPTI) as of Q1 2017, down from 86 in Q4 2016.
  • Funds reported $345M of Karyopharm Therapeutics stock for Q1 2017, up 44% quarter-over-quarter.
  • 13 funds opened new Karyopharm Therapeutics positions in Q1 2017 and 13 closed out, a net change of 0 holders.
  • The largest Karyopharm Therapeutics buyer in Q1 2017 was BlackRock, an estimated $26.8M added.
  • The largest Karyopharm Therapeutics seller in Q1 2017 was Millennium Management, an estimated $4.84M sold.

Based on aggregated 13F filings for Q1 2017.