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Karyopharm Therapeutics
KPTI

Overview Fund Activity

115 hedge funds and large institutions have $482M invested in Karyopharm Therapeutics in 2018 Q4 according to their latest regulatory filings, with 15 funds opening new positions, 49 increasing their positions, 34 reducing their positions, and 17 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
115
Holders Change
-4
Holders Change %
-3.36%
% of All Funds
2.57%
Holding in Top 10
1
Holding in Top 10 Change
–
Holding in Top 10 Change %
–
% of All Funds
0.02%
New
15
Increased
49
Reduced
34
Closed
17
Calls
$553K
Puts
$894K
Net Calls
-$341K
Net Calls Change
+$2.08M

Top Buyers

1
EA
Emerald Advisers
Pennsylvania
+$7.14M
2
EMFAT
Emerald Mutual Fund Advisers Trust
Pennsylvania
+$6.8M
3
CS
Candriam SCA
Luxembourg
+$6.62M
4
Point72 Asset Management
Point72 Asset Management
Connecticut
+$6.48M
5
Fidelity Investments
Fidelity Investments
Massachusetts
+$5.97M

Top Sellers

1
Vanguard Group
Vanguard Group
Pennsylvania
-$6.41M
2
Millennium Management
Millennium Management
New York
-$3.64M
3
SSA
Schonfeld Strategic Advisors
New York
-$2.77M
4
DAM
Doheny Asset Management
California
-$1.58M
5
Wellington Management Group
Wellington Management Group
Massachusetts
-$1.38M
Name Holding Trade Value Shares
Change 		Shares
Change %
Wellington Management Group
1
Wellington Management Group
Massachusetts
$77M -$1.38M -9,833 -2%
CCM
2
Consonance Capital Management
New York
$45.1M -$159K -1,133 -0.4%
PAI
3
Palo Alto Investors
California
$43.9M +$206K +1,469 +0.5%
BlackRock
4
BlackRock
New York
$39.9M -$24.5K -174 -0.1%
RCI
5
Ridgeback Capital Investments
Florida
$37M +$37M +263,013 New
State Street
6
State Street
Massachusetts
$23.6M +$5.46M +38,845 +30%
Fidelity Investments
7
Fidelity Investments
Massachusetts
$17.6M +$5.97M +42,490 +51%
Franklin Resources
8
Franklin Resources
California
$16.9M -$378K -2,688 -2%
CS
9
Candriam SCA
Luxembourg
$16.8M +$6.62M +47,136 +65%
Vanguard Group
10
Vanguard Group
Pennsylvania
$16.2M -$6.41M -45,600 -28%
Point72 Asset Management
11
Point72 Asset Management
Connecticut
$14.4M +$6.48M +46,081 +81%
EA
12
Emerald Advisers
Pennsylvania
$13.6M +$7.14M +50,827 +110%
EMFAT
13
Emerald Mutual Fund Advisers Trust
Pennsylvania
$12.9M +$6.8M +48,408 +112%
Dimensional Fund Advisors
14
Dimensional Fund Advisors
Texas
$6.31M +$3.87M +27,560 +159%
Two Sigma Investments
15
Two Sigma Investments
New York
$5.73M +$1.99M +14,147 +53%
Northern Trust
16
Northern Trust
Illinois
$5.7M -$125K -889 -2%
Geode Capital Management
17
Geode Capital Management
Massachusetts
$5.23M +$247K +1,757 +5%
Deutsche Bank
18
Deutsche Bank
Germany
$4.49M +$1.24M +8,850 +38%
DM
19
Deerfield Management
New York
$4.45M – – –
Millennium Management
20
Millennium Management
New York
$4.19M -$3.64M -25,889 -46%
PCA
21
Private Capital Advisors
Connecticut
$4.17M -$272K -1,933 -6%
Renaissance Technologies
22
Renaissance Technologies
New York
$3.99M +$3.33M +23,704 +503%
TCIM
23
TIAA CREF Investment Management
New York
$3.58M -$1.3M -9,239 -27%
Macquarie Group
24
Macquarie Group
Australia
$3.56M +$394K +2,806 +12%
TA
25
Teachers Advisors
New York
$3.2M +$32.6K +232 +1%
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