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Karyopharm Therapeutics

117 hedge funds and large institutions have $64.2M invested in Karyopharm Therapeutics in 2023 Q4 according to their latest regulatory filings, with 22 funds opening new positions, 25 increasing their positions, 41 reducing their positions, and 23 closing their positions.

New
Increased
Maintained
Reduced
Closed

1,654% more call options, than puts

Call options by funds: $456K | Put options by funds: $26K

0.18% less ownership

Funds ownership: 4.5%4.33% (-0.18%)

1% less funds holding

Funds holding: 118117 (-1)

4% less first-time investments, than exits

New positions opened: 22 | Existing positions closed: 23

38% less capital invested

Capital invested by funds: $103M → $64.2M (-$38.6M)

39% less repeat investments, than reductions

Existing positions increased: 25 | Existing positions reduced: 41

Holders
117
Holders Change
-1
Holders Change %
-0.85%
% of All Funds
1.71%
Holding in Top 10
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
New
22
Increased
25
Reduced
41
Closed
23
Calls
$456K
Puts
$26K
Net Calls
+$430K
Net Calls Change
-$173K
Name Holding Trade Value Shares
Change
Change in
Stake
BlackRock
1
BlackRock
New York
$8.71M -$912K -67,657 -9%
Vanguard Group
2
Vanguard Group
Pennsylvania
$7.53M -$98.6K -7,318 -1%
APM
3
Avidity Partners Management
Texas
$7.18M
PAI
4
Palo Alto Investors
California
$4.41M -$515K -38,246 -10%
Citadel Advisors
5
Citadel Advisors
Florida
$2.68M -$2.24K -166 -0.1%
Geode Capital Management
6
Geode Capital Management
Massachusetts
$2.06M +$85.6K +6,353 +4%
GCP
7
GSA Capital Partners
United Kingdom
$2.02M +$1.59M +117,979 +311%
State Street
8
State Street
Massachusetts
$1.78M +$9.68K +718 +0.5%
Renaissance Technologies
9
Renaissance Technologies
New York
$1.7M +$1.11M +82,265 +169%
Marshall Wace
10
Marshall Wace
United Kingdom
$1.66M -$230K -17,095 -12%
BNP Paribas Financial Markets
11
BNP Paribas Financial Markets
France
$1.53M +$97.3K +7,219 +7%
Morgan Stanley
12
Morgan Stanley
New York
$1.46M +$580K +43,056 +62%
Adage Capital Partners
13
Adage Capital Partners
Massachusetts
$1.44M +$1.49M +110,887 New
Millennium Management
14
Millennium Management
New York
$1.33M +$374K +27,757 +37%
CWG
15
C WorldWide Group
Denmark
$1.3M
Deutsche Bank
16
Deutsche Bank
Germany
$1.15M +$1.14M +84,585 +2,179%
Goldman Sachs
17
Goldman Sachs
New York
$1.12M -$556K -41,230 -32%
JP Morgan Chase
18
JP Morgan Chase
New York
$1.02M +$35.9K +2,666 +4%
AA
19
AlphaCentric Advisors
Puerto Rico
$973K
TC
20
Tejara Capital
United Kingdom
$892K -$41.4K -3,069 -4%
Northern Trust
21
Northern Trust
Illinois
$862K +$9.37K +695 +1%
Barclays
22
Barclays
United Kingdom
$839K -$164K -12,149 -16%
UOC
23
UBS O'Connor
Illinois
$694K -$66.8K -4,959 -8%
ACM
24
Altium Capital Management
New York
$640K
D.E. Shaw & Co
25
D.E. Shaw & Co
New York
$534K -$5.07K -376 -0.9%

KPTI Hedge Fund Activity: Q4 2023 in Review

117 of the 6,859 institutional investors tracked by Wall St. Rank reported a position in Karyopharm Therapeutics (KPTI) for Q4 2023, worth a combined $64.2M — down 38% from $103M a quarter earlier.

Sellers outnumbered buyers: 23 funds closed out of KPTI and 22 opened new positions — a net loss of 1 holder — while 41 trimmed existing stakes and 25 added.

The largest buyer was GSA Capital Partners, adding an estimated $1.59M. The largest seller was AIGH Capital Management, exiting entirely with an estimated $2.38M sold.

  • 117 institutional investors held Karyopharm Therapeutics (KPTI) as of Q4 2023, down from 118 in Q3 2023.
  • Funds reported $64.2M of Karyopharm Therapeutics stock for Q4 2023, down 38% quarter-over-quarter.
  • 22 funds opened new Karyopharm Therapeutics positions in Q4 2023 and 23 closed out, a net change of -1 holder.
  • The largest Karyopharm Therapeutics buyer in Q4 2023 was GSA Capital Partners, an estimated $1.59M added.
  • The largest Karyopharm Therapeutics seller in Q4 2023 was AIGH Capital Management, an estimated $2.38M sold.

Based on aggregated 13F filings for Q4 2023.