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Karyopharm Therapeutics
KPTI

Overview Fund Activity

117 hedge funds and large institutions have $64.2M invested in Karyopharm Therapeutics in 2023 Q4 according to their latest regulatory filings, with 22 funds opening new positions, 25 increasing their positions, 41 reducing their positions, and 23 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
117
Holders Change
-1
Holders Change %
-0.85%
% of All Funds
1.72%
Holding in Top 10
–
Holding in Top 10 Change
–
Holding in Top 10 Change %
–
% of All Funds
–
New
22
Increased
25
Reduced
41
Closed
23
Calls
$456K
Puts
$26K
Net Calls
+$430K
Net Calls Change
-$173K

Top Buyers

1
GCP
GSA Capital Partners
United Kingdom
$2.02M
2
Adage Capital Partners
Adage Capital Partners
Massachusetts
$1.44M
3
Deutsche Bank
Deutsche Bank
Germany
$1.15M
4
Renaissance Technologies
Renaissance Technologies
New York
$1.7M
5
Morgan Stanley
Morgan Stanley
New York
$1.46M

Top Sellers

1
ACM
AIGH Capital Management
Maryland
$0
2
ECM
ExodusPoint Capital Management
New York
$0
3
Jacobs Levy Equity Management
Jacobs Levy Equity Management
New Jersey
$246K
4
BlackRock
BlackRock
New York
$8.71M
5
PL
Parkwood LLC
Ohio
$0
Name Holding Trade Value Shares
Change 		Shares
Change %
BlackRock
1
BlackRock
New York
$8.71M -$878K -67,657 -9%
Vanguard Group
2
Vanguard Group
Pennsylvania
$7.53M -$95K -7,318 -1%
APM
3
Avidity Partners Management
Texas
$7.18M – – –
PAI
4
Palo Alto Investors
California
$4.41M -$496K -38,246 -10%
Citadel Advisors
5
Citadel Advisors
Florida
$2.68M -$2.15K -166 -0.1%
Geode Capital Management
6
Geode Capital Management
Massachusetts
$2.06M +$82.4K +6,353 +4%
GCP
7
GSA Capital Partners
United Kingdom
$2.02M +$1.53M +117,979 +311%
State Street
8
State Street
Massachusetts
$1.78M +$9.32K +718 +0.5%
Renaissance Technologies
9
Renaissance Technologies
New York
$1.7M +$1.07M +82,265 +169%
Marshall Wace
10
Marshall Wace
United Kingdom
$1.66M -$221K -17,095 -12%
BNP Paribas Financial Markets
11
BNP Paribas Financial Markets
France
$1.53M +$93.7K +7,219 +7%
Morgan Stanley
12
Morgan Stanley
New York
$1.46M +$559K +43,056 +62%
Adage Capital Partners
13
Adage Capital Partners
Massachusetts
$1.44M +$1.44M +110,887 New
Millennium Management
14
Millennium Management
New York
$1.33M +$360K +27,757 +37%
CWG
15
C WorldWide Group
Denmark
$1.3M – – –
Deutsche Bank
16
Deutsche Bank
Germany
$1.15M +$1.1M +84,585 +2,179%
Goldman Sachs
17
Goldman Sachs
New York
$1.12M -$535K -41,230 -32%
JPMorgan Chase & Co
18
JPMorgan Chase & Co
New York
$1.02M +$34.6K +2,666 +4%
AA
19
AlphaCentric Advisors
Puerto Rico
$973K – – –
TC
20
Tejara Capital
United Kingdom
$892K -$39.8K -3,069 -4%
Northern Trust
21
Northern Trust
Illinois
$862K +$9.02K +695 +1%
Barclays
22
Barclays
United Kingdom
$838K -$157K -12,149 -16%
UOC
23
UBS O'Connor
Illinois
$694K -$64.3K -4,959 -8%
ACM
24
Altium Capital Management
New York
$640K – – –
D.E. Shaw & Co
25
D.E. Shaw & Co
New York
$534K -$4.88K -376 -0.9%
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