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Karyopharm Therapeutics

52 hedge funds and large institutions have $19.5M invested in Karyopharm Therapeutics in 2025 Q3 according to their latest regulatory filings, with 7 funds opening new positions, 7 increasing their positions, 20 reducing their positions, and 5 closing their positions.

New
Increased
Maintained
Reduced
Closed

more first-time investments, than exits

New positions opened: | Existing positions closed:

more funds holding

Funds holding:

more capital invested

Capital invested by funds: $ → $

less ownership

Funds ownership:

26% less call options, than puts

Call options by funds: $5.74M | Put options by funds: $7.74M

65% less repeat investments, than reductions

Existing positions increased: 7 | Existing positions reduced: 20

Holders
52
Holders Change
Holders Change %
% of All Funds
Holding in Top 10
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
New
Increased
Reduced
Closed
Calls
$5.74M
Puts
$7.74M
Net Calls
Net Calls Change
Name Holding Trade Value Shares
Change
Change in
Stake
1
$4.58M
2
$2.76M
3
$2.67M
4
$1.52M
5
$935K
6
$880K
7
$840K
8
$654K
9
$610K
10
$448K
11
$423K
12
$390K
13
$303K
14
$262K
15
$231K
16
$228K
17
$183K
18
$178K
19
$170K
20
$169K
21
$164K
22
$163K
23
$123K
24
$95.2K
25
$94.2K