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Karyopharm Therapeutics
KPTI

Overview Fund Activity

71 hedge funds and large institutions have $587M invested in Karyopharm Therapeutics in 2014 Q3 according to their latest regulatory filings, with 15 funds opening new positions, 33 increasing their positions, 15 reducing their positions, and 22 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
71
Holders Change
-7
Holders Change %
-8.97%
% of All Funds
2.06%
Holding in Top 10
2
Holding in Top 10 Change
–
Holding in Top 10 Change %
–
% of All Funds
0.06%
New
15
Increased
33
Reduced
15
Closed
22
Calls
$1.99M
Puts
$2.21M
Net Calls
-$216K
Net Calls Change
-$216K

Top Buyers

1
Fidelity Investments
Fidelity Investments
Massachusetts
$142M
2
PHS
PFM Health Sciences
California
$39.3M
3
State Street
State Street
Massachusetts
$19.8M
4
SAM
Sectoral Asset Management
Quebec, Canada
$17.1M
5
Franklin Resources
Franklin Resources
California
$154M

Top Sellers

1
FCMI
Foresite Capital Management I
California
$37.6M
2
VAM
Visium Asset Management
New York
$0
3
Citadel Advisors
Citadel Advisors
Florida
$0
4
GPP
Great Point Partners
Connecticut
$0
5
PA
Perceptive Advisors
New York
$0
Name Holding Trade Value Shares
Change 		Shares
Change %
Franklin Resources
1
Franklin Resources
California
$154M +$6.19M +11,804 +4%
Fidelity Investments
2
Fidelity Investments
Massachusetts
$142M +$22.5M +42,994 +19%
PHS
3
PFM Health Sciences
California
$39.3M +$16.2M +30,868 +70%
FCMI
4
Foresite Capital Management I
California
$37.6M -$10.5M -20,019 -22%
BA
5
BlackRock Advisors
Delaware
$25.3M -$446K -851 -2%
State Street
6
State Street
Massachusetts
$19.8M +$13.9M +26,482 +235%
SAM
7
Sectoral Asset Management
Quebec, Canada
$17.1M +$7.68M +14,653 +82%
AllianceBernstein
8
AllianceBernstein
Tennessee
$16.5M +$2.08M +3,977 +14%
CAM
9
Cormorant Asset Management
Massachusetts
$13.5M – – –
Vanguard Group
10
Vanguard Group
Pennsylvania
$13.3M +$2.96M +5,653 +29%
Wellington Management Group
11
Wellington Management Group
Massachusetts
$11.5M -$355K -677 -3%
BFA
12
BlackRock Fund Advisors
California
$11.3M +$570K +1,087 +5%
BG
13
BlackRock Group
United Kingdom
$8.07M -$24.1K -46 -0.3%
Lord, Abbett & Co
14
Lord, Abbett & Co
New Jersey
$5.83M +$1.56M +2,983 +37%
Northern Trust
15
Northern Trust
Illinois
$5.28M +$2.16M +4,119 +69%
BIT
16
BlackRock Institutional Trust
California
$4.93M +$264K +503 +6%
TG
17
TCW Group
California
$4.79M +$526K +1,004 +12%
BlackRock
18
BlackRock
New York
$3.59M -$198K -377 -5%
TCM
19
Tekla Capital Management
Massachusetts
$3.56M +$3.56M +6,798 New
PC
20
PointState Capital
New York
$3.49M -$1.75M -3,333 -33%
Balyasny Asset Management
21
Balyasny Asset Management
Illinois
$3.48M +$3.48M +6,642 New
BBA
22
Baker Bros. Advisors
New York
$3.29M – – –
GC
23
Guggenheim Capital
Illinois
$2.98M -$172K -329 -5%
Deutsche Bank
24
Deutsche Bank
Germany
$2.8M +$2.65M +5,060 +1,833%
DCM
25
Driehaus Capital Management
Illinois
$2.76M +$71.3K +136 +3%
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