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Karyopharm Therapeutics

71 hedge funds and large institutions have $587M invested in Karyopharm Therapeutics in 2014 Q3 according to their latest regulatory filings, with 15 funds opening new positions, 33 increasing their positions, 15 reducing their positions, and 22 closing their positions.

New
Increased
Maintained
Reduced
Closed

120% more repeat investments, than reductions

Existing positions increased: 33 | Existing positions reduced: 15

0% more funds holding in top 10

Funds holding in top 10: 22 (0)

10% less call options, than puts

Call options by funds: $1.99M | Put options by funds: $2.21M

9% less funds holding

Funds holding: 7871 (-7)

17% less capital invested

Capital invested by funds: $704M → $587M (-$117M)

32% less first-time investments, than exits

New positions opened: 15 | Existing positions closed: 22

Holders
71
Holders Change
-7
Holders Change %
-8.97%
% of All Funds
2.06%
Holding in Top 10
2
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
0.06%
New
15
Increased
33
Reduced
15
Closed
22
Calls
$1.99M
Puts
$2.21M
Net Calls
-$216K
Net Calls Change
-$216K
Name Holding Trade Value Shares
Change
Change in
Stake
Franklin Resources
1
Franklin Resources
California
$154M +$6.66M +11,804 +4%
Fidelity Investments
2
Fidelity Investments
Massachusetts
$142M +$24.3M +42,994 +19%
PHS
3
PFM Health Sciences
California
$39.3M +$17.4M +30,868 +70%
FCMI
4
Foresite Capital Management I
California
$37.6M -$11.3M -20,019 -22%
BA
5
BlackRock Advisors
Delaware
$25.3M -$480K -851 -2%
State Street
6
State Street
Massachusetts
$19.8M +$14.9M +26,482 +235%
SAM
7
Sectoral Asset Management
Quebec, Canada
$17.1M +$8.27M +14,653 +82%
AllianceBernstein
8
AllianceBernstein
Tennessee
$16.5M +$2.24M +3,977 +14%
CAM
9
Cormorant Asset Management
Massachusetts
$13.5M
Vanguard Group
10
Vanguard Group
Pennsylvania
$13.3M +$3.19M +5,653 +29%
Wellington Management Group
11
Wellington Management Group
Massachusetts
$11.5M -$382K -677 -3%
BFA
12
BlackRock Fund Advisors
California
$11.3M +$613K +1,087 +5%
BG
13
BlackRock Group
United Kingdom
$8.06M -$26K -46 -0.3%
Lord, Abbett & Co
14
Lord, Abbett & Co
New Jersey
$5.83M +$1.68M +2,983 +37%
Northern Trust
15
Northern Trust
Illinois
$5.28M +$2.32M +4,119 +69%
BIT
16
BlackRock Institutional Trust
California
$4.93M +$284K +503 +6%
TG
17
TCW Group
California
$4.79M +$567K +1,004 +12%
BlackRock
18
BlackRock
New York
$3.59M -$213K -377 -5%
TCM
19
Tekla Capital Management
Massachusetts
$3.56M +$3.84M +6,798 New
PC
20
PointState Capital
New York
$3.49M -$1.88M -3,333 -33%
Balyasny Asset Management
21
Balyasny Asset Management
Illinois
$3.48M +$3.75M +6,642 New
BBA
22
Baker Bros. Advisors
New York
$3.29M
GC
23
Guggenheim Capital
Illinois
$2.98M -$186K -329 -5%
Deutsche Bank
24
Deutsche Bank
Germany
$2.79M +$2.86M +5,060 +1,833%
DCM
25
Driehaus Capital Management
Illinois
$2.75M +$76.8K +136 +3%

KPTI Hedge Fund Activity: Q3 2014 in Review

71 of the 3,447 institutional investors tracked by Wall St. Rank reported a position in Karyopharm Therapeutics (KPTI) for Q3 2014, worth a combined $587M — down 17% from $704M a quarter earlier.

Sellers outnumbered buyers: 22 funds closed out of KPTI and 15 opened new positions — a net loss of 7 holders — while 15 trimmed existing stakes and 33 added.

The largest buyer was Fidelity Investments, adding an estimated $24.3M. The largest seller was Foresite Capital Management I, cutting an estimated $11.3M.

  • 71 institutional investors held Karyopharm Therapeutics (KPTI) as of Q3 2014, down from 78 in Q2 2014.
  • Funds reported $587M of Karyopharm Therapeutics stock for Q3 2014, down 17% quarter-over-quarter.
  • 15 funds opened new Karyopharm Therapeutics positions in Q3 2014 and 22 closed out, a net change of -7 holders.
  • The largest Karyopharm Therapeutics buyer in Q3 2014 was Fidelity Investments, an estimated $24.3M added.
  • The largest Karyopharm Therapeutics seller in Q3 2014 was Foresite Capital Management I, an estimated $11.3M sold.

Based on aggregated 13F filings for Q3 2014.