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Karyopharm Therapeutics

168 hedge funds and large institutions have $987M invested in Karyopharm Therapeutics in 2020 Q4 according to their latest regulatory filings, with 32 funds opening new positions, 61 increasing their positions, 44 reducing their positions, and 21 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
168
Holders Change
Holders Change %
% of All Funds
Holding in Top 10
2
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
New
Increased
Reduced
Closed
Calls
$11.2M
Puts
$7.99M
Net Calls
Net Calls Change

Top Buyers

1 +$36.1M
2 +$12.9M
3 +$9.29M
4
State Street
State Street
Massachusetts
+$8.53M
5
Alkeon Capital Management
Alkeon Capital Management
New York
+$7.76M

Top Sellers

1 -$87.6M
2 -$19.3M
3 -$15.6M
4
Adage Capital Partners
Adage Capital Partners
Massachusetts
-$11.6M
5
Two Sigma Advisers
Two Sigma Advisers
New York
-$10.5M
Name Holding Trade Value Shares
Change
Change in
Stake
126
$207K
127
$192K
128
$185K
129
$179K
130
$176K
131
$176K
132
$170K
133
$170K
134
$169K
135
$161K
136
$156K
137
$129K
138
$96K
139
$93K
140
$92K
141
$63K
142
$54K
143
$50K
144
$47K
145
$34K
146
$26K
147
$26K
148
$23K
149
$22K
150
$18K