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Karyopharm Therapeutics

157 hedge funds and large institutions have $949M invested in Karyopharm Therapeutics in 2020 Q3 according to their latest regulatory filings, with 29 funds opening new positions, 55 increasing their positions, 53 reducing their positions, and 27 closing their positions.

New
Increased
Maintained
Reduced
Closed

61% more call options, than puts

Call options by funds: $7.81M | Put options by funds: $4.85M

1% more funds holding

Funds holding: 155157 (+2)

7% more first-time investments, than exits

New positions opened: 29 | Existing positions closed: 27

4% more repeat investments, than reductions

Existing positions increased: 55 | Existing positions reduced: 53

0.45% less ownership

Funds ownership: 6.36%5.91% (-0.45%)

28% less capital invested

Capital invested by funds: $1.32B → $949M (-$372M)

50% less funds holding in top 10

Funds holding in top 10: 42 (-2)

Holders
157
Holders Change
+2
Holders Change %
+1.29%
% of All Funds
3.17%
Holding in Top 10
2
Holding in Top 10 Change
-2
Holding in Top 10 Change %
-50%
% of All Funds
0.04%
New
29
Increased
55
Reduced
53
Closed
27
Calls
$7.81M
Puts
$4.85M
Net Calls
+$2.96M
Net Calls Change
-$5.5M
Name Holding Trade Value Shares
Change
Change in
Stake
Zurich Cantonal Bank
126
Zurich Cantonal Bank
Switzerland
$87K
Royal Bank of Canada
127
Royal Bank of Canada
Ontario, Canada
$81K +$978 +4 +1%
PNC Financial Services Group
128
PNC Financial Services Group
Pennsylvania
$55K
Nisa Investment Advisors
129
Nisa Investment Advisors
Missouri
$51K +$43K +176 +309%
Bank of Montreal
130
Bank of Montreal
Ontario, Canada
$47K -$38.2K -156 -42%
Canada Life
131
Canada Life
Manitoba, Canada
$44K
GT
132
Glenmede Trust
Pennsylvania
$42K +$22K +90 +87%
QT
133
Quantbot Technologies
New York
$29K +$33.3K +136 New
TJHA
134
Thomas J. Herzfeld Advisors
Florida
$22K
PHK
135
Point72 Hong Kong
Hong Kong
$20K -$29.8K -122 -57%
TCOV
136
Trust Company of Vermont
Vermont
$20K -$9.78K -40 -30%
PCG
137
Private Capital Group
Connecticut
$15K
CHAM
138
Clear Harbor Asset Management
Connecticut
$14.6K +$16.4K +67 New
Northwestern Mutual Wealth Management
139
Northwestern Mutual Wealth Management
Wisconsin
$14K +$15.9K +65 New
ASN
140
Advisory Services Network
Georgia
$13K +$14.7K +60 New
CCM
141
Chiron Capital Management
Florida
$12K +$13K +53 New
OSAM
142
O'Shaughnessy Asset Management
Connecticut
$11K
GEA
143
Glen Eagle Advisors
New Jersey
$10.4K +$5.87K +24 +104%
AF
144
Advisornet Financial
Minnesota
$9K
PCM
145
Penserra Capital Management
California
$9K +$10.3K +42 New
CAPTRUST Financial Advisors
146
CAPTRUST Financial Advisors
North Carolina
$7K
Daiwa Securities Group
147
Daiwa Securities Group
Japan
$6K +$978 +4 +17%
KFS
148
Kelly Financial Services
Massachusetts
$3.65K
Rockefeller Capital Management
149
Rockefeller Capital Management
New York
$3K +$1.71K +7 +64%
Millennium Management
150
Millennium Management
New York
$2.41K -$1.19M -4,848 -31%

KPTI Hedge Fund Activity: Q3 2020 in Review

157 of the 4,956 institutional investors tracked by Wall St. Rank reported a position in Karyopharm Therapeutics (KPTI) for Q3 2020, worth a combined $949M — down 28% from $1.32B a quarter earlier.

Buyers outnumbered sellers: 29 funds opened new KPTI positions and 27 closed out — a net gain of 2 holders — while 55 added to existing stakes and 53 trimmed.

The largest buyer was Two Sigma Investments, adding an estimated $17.2M. The largest seller was Consonance Capital Management, exiting entirely with an estimated $123M sold.

  • 157 institutional investors held Karyopharm Therapeutics (KPTI) as of Q3 2020, up from 155 in Q2 2020.
  • Funds reported $949M of Karyopharm Therapeutics stock for Q3 2020, down 28% quarter-over-quarter.
  • 29 funds opened new Karyopharm Therapeutics positions in Q3 2020 and 27 closed out, a net change of +2 holders.
  • The largest Karyopharm Therapeutics buyer in Q3 2020 was Two Sigma Investments, an estimated $17.2M added.
  • The largest Karyopharm Therapeutics seller in Q3 2020 was Consonance Capital Management, an estimated $123M sold.

Based on aggregated 13F filings for Q3 2020.