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Karyopharm Therapeutics
KPTI

Overview Fund Activity

114 hedge funds and large institutions have $58.6M invested in Karyopharm Therapeutics in 2024 Q2 according to their latest regulatory filings, with 27 funds opening new positions, 24 increasing their positions, 33 reducing their positions, and 26 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
114
Holders Change
+1
Holders Change %
+0.88%
% of All Funds
1.66%
Holding in Top 10
–
Holding in Top 10 Change
–
Holding in Top 10 Change %
–
% of All Funds
–
New
27
Increased
24
Reduced
33
Closed
26
Calls
$1.19M
Puts
$89K
Net Calls
+$1.1M
Net Calls Change
+$1.09M

Top Buyers

1
OM
Opaleye Management
Massachusetts
+$1.24M
2
Jane Street
Jane Street
New York
+$1.2M
3
KCM
Kennedy Capital Management
Missouri
+$1.04M
4
Millennium Management
Millennium Management
New York
+$787K
5
Adage Capital Partners
Adage Capital Partners
Massachusetts
+$711K

Top Sellers

1
APM
Avidity Partners Management
Texas
-$5.45M
2
BlackRock
BlackRock
New York
-$4.58M
3
State Street
State Street
Massachusetts
-$1.59M
4
Geode Capital Management
Geode Capital Management
Massachusetts
-$1.05M
5
Nuveen Asset Management
Nuveen Asset Management
Illinois
-$743K
Name Holding Trade Value Shares
Change 		Shares
Change %
HI
101
Harbour Investments
Wisconsin
$1.13K – – –
New York State Common Retirement Fund
102
New York State Common Retirement Fund
New York
$1K -$21K -1,346 -95%
AWM
103
Activest Wealth Management
Florida
$868 +$868 +67 New
AAP
104
Arax Advisory Partners
Colorado
$467 +$467 +36 New
AF
105
Allworth Financial
California
$445 – – –
BGAI
106
Bruce G. Allen Investments
Colorado
$440 – – –
PCA
107
Providence Capital Advisors
North Carolina
$271 – – –
KFS
108
Kelly Financial Services
Massachusetts
$217 – – –
AF
109
Advisornet Financial
Minnesota
$174 – – –
Nisa Investment Advisors
110
Nisa Investment Advisors
Missouri
$43 -$143 -10 -77%
WBC
111
West Branch Capital
Massachusetts
$42 – – –
CIBC Private Wealth Group
112
CIBC Private Wealth Group
Georgia
$40 – – –
JWM
113
Janiczek Wealth Management
Colorado
$15 – – –
Wells Fargo
114
Wells Fargo
California
$12 -$27.1K -2,259 -100%
Nuveen Asset Management
115
Nuveen Asset Management
Illinois
– -$743K -32,824 Closed
PAM
116
Panagora Asset Management
Massachusetts
– -$347K -15,328 Closed
AllianceBernstein
117
AllianceBernstein
Tennessee
– -$291K -12,854 Closed
Connor, Clark & Lunn Investment Management (CC&L)
118
Connor, Clark & Lunn Investment Management (CC&L)
British Columbia, Canada
– -$115K -5,088 Closed
MIM
119
MetLife Investment Management
New Jersey
– -$91.4K -4,037 Closed
Simplex Trading
120
Simplex Trading
Illinois
– -$84K -3,732 Closed
AIG
121
American International Group
New York
– -$84.3K -3,721 Closed
VOYA Investment Management
122
VOYA Investment Management
Georgia
– -$58.6K -2,587 Closed
Group One Trading
123
Group One Trading
Illinois
– -$56.1K -2,475 Closed
Manulife (Manufacturers Life Insurance)
124
Manulife (Manufacturers Life Insurance)
Ontario, Canada
– -$54.2K -2,391 Closed
Principal Financial Group
125
Principal Financial Group
Iowa
– -$50.1K -2,211 Closed
2 3 4
5
6