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Karyopharm Therapeutics

143 hedge funds and large institutions have $347M invested in Karyopharm Therapeutics in 2021 Q4 according to their latest regulatory filings, with 29 funds opening new positions, 51 increasing their positions, 46 reducing their positions, and 17 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
143
Holders Change
+9
Holders Change %
+6.72%
% of All Funds
2.21%
Holding in Top 10
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-100%
% of All Funds
New
29
Increased
51
Reduced
46
Closed
17
Calls
$4.62M
Puts
$10.3M
Net Calls
-$5.68M
Net Calls Change
+$171K
Name Holding Trade Value Shares
Change
Shares
Change %
XT
101
XTX Topco
Cayman Islands
$84K -$20.8K -215 -20%
Creative Planning
102
Creative Planning
Kansas
$84K -$19.2K -200 -19%
Teacher Retirement System of Texas
103
Teacher Retirement System of Texas
Texas
$84K +$84K +874 New
MLICM
104
Metropolitan Life Insurance Company (MetLife)
New York
$83.5K +$9.26K +96 +12%
AB
105
Amalgamated Bank
New York
$82K -$2.32K -24 -3%
AT
106
American Trust
Kentucky
$81K +$81K +837 New
GCM
107
Graham Capital Management
Connecticut
$81K +$81K +841 New
EFM
108
E Fund Management
China
$80K -$52.5K -542 -40%
Principal Financial Group
109
Principal Financial Group
Iowa
$78K -$117K -1,213 -60%
Janus Henderson Group
110
Janus Henderson Group
United Kingdom
$78K +$78K +811 New
Walleye Trading
111
Walleye Trading
New York
$59K +$59K +607 New
Marshall Wace
112
Marshall Wace
United Kingdom
$57K +$57K +600 New
Belvedere Trading
113
Belvedere Trading
Illinois
$44K +$44K +358 New
AIP
114
Ameritas Investment Partners
Nebraska
$40K
QT
115
Quantbot Technologies
New York
$39K +$37K +386 +1,838%
Zurich Cantonal Bank
116
Zurich Cantonal Bank
Switzerland
$38K
Osaic Holdings
117
Osaic Holdings
Arizona
$33K -$104K -1,074 -76%
Rockefeller Capital Management
118
Rockefeller Capital Management
New York
$26K +$2.48K +26 +11%
SCA
119
Snowden Capital Advisors
New York
$26K +$26K +273 New
PNC Financial Services Group
120
PNC Financial Services Group
Pennsylvania
$24K
Canada Life
121
Canada Life
Manitoba, Canada
$19K
FCMT
122
Founders Capital Management (Texas)
Texas
$19K
US Bancorp
123
US Bancorp
Minnesota
$18K +$4.21K +43 +30%
S
124
SignatureFD
Georgia
$11K -$746 -8 -6%
PHK
125
Point72 Hong Kong
Hong Kong
$8K -$60.4K -634 -88%