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Karyopharm Therapeutics

168 hedge funds and large institutions have $987M invested in Karyopharm Therapeutics in 2020 Q4 according to their latest regulatory filings, with 32 funds opening new positions, 61 increasing their positions, 44 reducing their positions, and 21 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
168
Holders Change
Holders Change %
% of All Funds
Holding in Top 10
2
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
New
Increased
Reduced
Closed
Calls
$11.2M
Puts
$7.99M
Net Calls
Net Calls Change

Top Buyers

1 +$36.1M
2 +$12.9M
3 +$9.29M
4
State Street
State Street
Massachusetts
+$8.53M
5
Alkeon Capital Management
Alkeon Capital Management
New York
+$7.76M

Top Sellers

1 -$87.6M
2 -$19.3M
3 -$15.6M
4
Adage Capital Partners
Adage Capital Partners
Massachusetts
-$11.6M
5
Two Sigma Advisers
Two Sigma Advisers
New York
-$10.5M
Name Holding Trade Value Shares
Change
Change in
Stake
101
$363K
102
$359K
103
$356K
104
$349K
105
$345K
106
$339K
107
$337K
108
$330K
109
$310K
110
$297K
111
$294K
112
$285K
113
$279K
114
$272K
115
$267K
116
$267K
117
$263K
118
$263K
119
$262K
120
$247K
121
$239K
122
$233K
123
$232K
124
$231K
125
$226K