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Karyopharm Therapeutics
KPTI

106 hedge funds and large institutions have $563M invested in Karyopharm Therapeutics in 2019 Q3 according to their latest regulatory filings, with 24 funds opening new positions, 40 increasing their positions, 25 reducing their positions, and 21 closing their positions.

New
Increased
Maintained
Reduced
Closed

84% more capital invested

Capital invested by funds: $306M → $563M (+$256M)

60% more repeat investments, than reductions

Existing positions increased: 40 | Existing positions reduced: 25

14% more first-time investments, than exits

New positions opened: 24 | Existing positions closed: 21

3% more funds holding

Funds holding: 103 → 106 (+3)

0.69% more ownership

Funds ownership: 5.6% → 6.3% (+0.69%)

3% less call options, than puts

Call options by funds: $3.67M | Put options by funds: $3.78M

Holders
106
Holders Change
+3
Holders Change %
+2.91%
% of All Funds
2.32%
Holding in Top 10
1
Holding in Top 10 Change
+1
Holding in Top 10 Change %
% of All Funds
0.02%
New
24
Increased
40
Reduced
25
Closed
21
Calls
$3.67M
Puts
$3.78M
Net Calls
-$117K
Net Calls Change
-$3.89M

Top Buyers

Rank Fund Capital Flow
1
ACA
Avoro Capital Advisors
New York
+$54.7M
2
State Street
State Street
Massachusetts
+$18.3M
3
Adage Capital Partners
Adage Capital Partners
Massachusetts
+$15.4M
4
ECP
Elk Creek Partners
Colorado
+$11.5M
5
Millennium Management
Millennium Management
New York
+$11M

Top Sellers

Rank Fund Capital Flow
1
Wellington Management Group
Wellington Management Group
Massachusetts
-$24.2M
2
O
OrbiMed
New York
-$18.8M
3
Point72 Asset Management
Point72 Asset Management
Connecticut
-$15.6M
4
CS
Candriam SCA
Luxembourg
-$7.9M
5
PAI
Palo Alto Investors
California
-$3.8M
Name Holding Trade Value Shares
Change 		Change in
Stake
IUHSA
101
Itau Unibanco Holding S.A.
Brazil
$9K – – –
Daiwa Securities Group
102
Daiwa Securities Group
Japan
$4K – – –
TFS
103
TrustCore Financial Services
Tennessee
$3K – – –
US Bancorp
104
US Bancorp
Minnesota
$2K -$36.5K -269 -95%
MAM
105
Meeder Asset Management
Ohio
$2K +$2.17K +16 New
NFG
106
Next Financial Group
Texas
$1K -$8.68K -64 -90%
Point72 Asset Management
107
Point72 Asset Management
Connecticut
– -$15.6M -173,088 Closed
BI
108
BVF Inc
California
– -$2.13M -23,684 Closed
USAA
109
United Services Automobile Association
Texas
– -$652K -7,259 Closed
ARTA
110
A.R.T. Advisors
New York
– -$617K -6,862 Closed
SIM
111
Spark Investment Management
New York
– -$520K -5,797 Closed
CSS
112
Cubist Systematic Strategies
Connecticut
– -$506K -5,634 Closed
Renaissance Technologies
113
Renaissance Technologies
New York
– -$440K -4,901 Closed
Connor, Clark & Lunn Investment Management (CC&L)
114
Connor, Clark & Lunn Investment Management (CC&L)
British Columbia, Canada
– -$346K -3,845 Closed
BFM
115
Boothbay Fund Management
New York
– -$333K -2,455 Closed
CM
116
Caption Management
Oklahoma
– -$271K -2,000 Closed
PAM
117
Premier Asset Management
Illinois
– -$160K -1,783 Closed
Squarepoint
118
Squarepoint
New York
– -$117K -1,304 Closed
TI
119
Trexquant Investment
Connecticut
– -$101K -1,127 Closed
Envestnet Asset Management
120
Envestnet Asset Management
Illinois
– -$72K -799 Closed
Canada Life
121
Canada Life
Manitoba, Canada
– -$34K -379 Closed
AG
122
Aperio Group
California
– -$24K -262 Closed
PCM
123
Prelude Capital Management
New York
– -$9K -102 Closed
FIA
124
FNY Investment Advisers
New York
– -$5K -67 Closed
JFA
125
JNBA Financial Advisors
Minnesota
– -$2K -27 Closed
2 3 4
5
6

KPTI Hedge Fund Activity: Q3 2019 in Review

106 of the 4,561 institutional investors tracked by Wall St. Rank reported a position in Karyopharm Therapeutics (KPTI) for Q3 2019, worth a combined $563M — up 84% from $306M a quarter earlier.

Buyers outnumbered sellers: 24 funds opened new KPTI positions and 21 closed out — a net gain of 3 holders — while 40 added to existing stakes and 25 trimmed.

The largest buyer was Avoro Capital Advisors, opening a new position worth an estimated $54.7M. The largest seller was Wellington Management Group, cutting an estimated $24.2M.

  • 106 institutional investors held Karyopharm Therapeutics (KPTI) as of Q3 2019, up from 103 in Q2 2019.
  • Funds reported $563M of Karyopharm Therapeutics stock for Q3 2019, up 84% quarter-over-quarter.
  • 24 funds opened new Karyopharm Therapeutics positions in Q3 2019 and 21 closed out, a net change of +3 holders.
  • The largest Karyopharm Therapeutics buyer in Q3 2019 was Avoro Capital Advisors, an estimated $54.7M added.
  • The largest Karyopharm Therapeutics seller in Q3 2019 was Wellington Management Group, an estimated $24.2M sold.

Based on aggregated 13F filings for Q3 2019.