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Karyopharm Therapeutics
KPTI

Overview Fund Activity

168 hedge funds and large institutions have $987M invested in Karyopharm Therapeutics in 2020 Q4 according to their latest regulatory filings, with 32 funds opening new positions, 61 increasing their positions, 44 reducing their positions, and 21 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
168
Holders Change
+11
Holders Change %
+7.01%
% of All Funds
2.98%
Holding in Top 10
2
Holding in Top 10 Change
–
Holding in Top 10 Change %
–
% of All Funds
0.04%
New
32
Increased
61
Reduced
44
Closed
21
Calls
$11.2M
Puts
$7.99M
Net Calls
+$3.23M
Net Calls Change
+$273K

Top Buyers

1
Millennium Management
Millennium Management
New York
+$36.1M
2
LCM
Laurion Capital Management
New York
+$12.9M
3
CWG
C WorldWide Group
Denmark
+$9.29M
4
State Street
State Street
Massachusetts
+$8.53M
5
Alkeon Capital Management
Alkeon Capital Management
New York
+$7.76M

Top Sellers

1
ACA
Avoro Capital Advisors
New York
-$87.6M
2
Two Sigma Investments
Two Sigma Investments
New York
-$19.3M
3
D.E. Shaw & Co
D.E. Shaw & Co
New York
-$15.6M
4
Adage Capital Partners
Adage Capital Partners
Massachusetts
-$11.6M
5
Two Sigma Advisers
Two Sigma Advisers
New York
-$10.5M
Name Holding Trade Value Shares
Change 		Shares
Change %
Creative Planning
76
Creative Planning
Kansas
$822K +$549K +2,363 +201%
PAM
77
Panagora Asset Management
Massachusetts
$801K – – –
VF
78
Virtu Financial
New York
$775K +$775K +3,339 New
SEC
79
Seven Eight Capital
New York
$721K -$479K -2,066 -40%
TRSOTSOK
80
Teachers Retirement System of the State of Kentucky
Kentucky
$719K +$318K +1,371 +79%
APWA
81
Atlas Private Wealth Advisors
New Jersey
$691K -$46.4K -200 -6%
Jacobs Levy Equity Management
82
Jacobs Levy Equity Management
New Jersey
$658K +$658K +2,835 New
Manulife (Manufacturers Life Insurance)
83
Manulife (Manufacturers Life Insurance)
Ontario, Canada
$632K +$19.3K +83 +3%
Two Sigma Investments
84
Two Sigma Investments
New York
$622K -$19.3M -83,162 -97%
VEA
85
Virtus ETF Advisers
New York
$605K +$63.4K +273 +12%
MS
86
Maven Securities
Jersey
$572K +$572K +2,462 New
TI
87
Trexquant Investment
Connecticut
$563K +$563K +2,427 New
DekaBank Deutsche Girozentrale
88
DekaBank Deutsche Girozentrale
Germany
$547K – – –
SEI Investments
89
SEI Investments
Pennsylvania
$532K -$10.3K -45 -2%
Principal Financial Group
90
Principal Financial Group
Iowa
$515K +$151K +651 +42%
TRCT
91
Tower Research Capital (TRC)
New York
$505K +$408K +1,756 +418%
MIM
92
MetLife Investment Management
New Jersey
$487K – – –
Lazard Asset Management
93
Lazard Asset Management
New York
$477K +$477K +2,056 New
VOYA Investment Management
94
VOYA Investment Management
Georgia
$473K -$12.8K -55 -3%
PCA
95
Private Capital Advisors
Connecticut
$456K +$456K +1,962 New
TD Asset Management
96
TD Asset Management
Ontario, Canada
$450K – – –
ProShare Advisors
97
ProShare Advisors
Maryland
$416K +$100K +431 +32%
State Board of Administration of Florida Retirement System
98
State Board of Administration of Florida Retirement System
Florida
$408K – – –
WMSA
99
Weiss Multi-Strategy Advisers
New York
$388K +$45.7K +197 +13%
Invesco
100
Invesco
Georgia
$385K +$157K +676 +69%
2 3
4
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