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Karyopharm Therapeutics
KPTI

Overview Fund Activity

146 hedge funds and large institutions have $1.13B invested in Karyopharm Therapeutics in 2019 Q4 according to their latest regulatory filings, with 52 funds opening new positions, 41 increasing their positions, 39 reducing their positions, and 11 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
146
Holders Change
+40
Holders Change %
+37.74%
% of All Funds
2.88%
Holding in Top 10
5
Holding in Top 10 Change
+4
Holding in Top 10 Change %
+400%
% of All Funds
0.1%
New
52
Increased
41
Reduced
39
Closed
11
Calls
$16.5M
Puts
$15.6M
Net Calls
+$838K
Net Calls Change
+$955K

Top Buyers

1
Adage Capital Partners
Adage Capital Partners
Massachusetts
+$40M
2
D.E. Shaw & Co
D.E. Shaw & Co
New York
+$18.9M
3
Federated Hermes
Federated Hermes
Pennsylvania
+$15.7M
4
Two Sigma Investments
Two Sigma Investments
New York
+$14M
5
ACP
Acuta Capital Partners
California
+$6.76M

Top Sellers

1
Wellington Management Group
Wellington Management Group
Massachusetts
-$84.3M
2
Millennium Management
Millennium Management
New York
-$24.4M
3
EA
Emerald Advisers
Pennsylvania
-$19.1M
4
EMFAT
Emerald Mutual Fund Advisers Trust
Pennsylvania
-$18.1M
5
ECP
Elk Creek Partners
Colorado
-$15.5M
Name Holding Trade Value Shares
Change 		Shares
Change %
AIM
76
Aigen Investment Management
New York
$924K +$924K +3,213 New
SEI Investments
77
SEI Investments
Pennsylvania
$919K +$584K +2,033 +175%
QSS
78
Quantitative Systematic Strategies
Florida
$851K +$334K +1,161 +65%
LTFS
79
Ladenburg Thalmann Financial Services
Florida
$804K +$2.3K +8 +0.3%
WP
80
Woodline Partners
California
$732K +$732K +2,546 New
VEA
81
Virtus ETF Advisers
New York
$730K -$118K -410 -14%
AIG
82
American International Group
New York
$715K +$3.74K +13 +0.5%
CCIA
83
Campbell & Co Investment Adviser
Maryland
$680K +$680K +2,364 New
Manulife (Manufacturers Life Insurance)
84
Manulife (Manufacturers Life Insurance)
Ontario, Canada
$651K -$35.1K -122 -5%
JGC
85
J. Goldman & Co
New York
$643K -$5.29M -18,403 -89%
MIM
86
MetLife Investment Management
New Jersey
$565K – – –
VOYA Investment Management
87
VOYA Investment Management
Georgia
$561K +$110K +383 +24%
Citigroup
88
Citigroup
New York
$526K -$1.93M -6,715 -79%
Simplex Trading
89
Simplex Trading
Illinois
$498K +$472K +1,644 +1,807%
FMBTD
90
First Midwest Bank Trust Division
Illinois
$476K -$480K -1,667 -50%
SEC
91
Seven Eight Capital
New York
$466K +$466K +1,620 New
Squarepoint
92
Squarepoint
New York
$448K +$448K +1,559 New
ARTA
93
A.R.T. Advisors
New York
$432K +$432K +1,502 New
ProShare Advisors
94
ProShare Advisors
Maryland
$415K -$34.5K -120 -8%
MLICM
95
Metropolitan Life Insurance Company (MetLife)
New York
$394K -$14.7K -51 -4%
Man Group
96
Man Group
United Kingdom
$380K -$23K -80 -6%
TRSOTSOK
97
Teachers Retirement System of the State of Kentucky
Kentucky
$358K – – –
State Board of Administration of Florida Retirement System
98
State Board of Administration of Florida Retirement System
Florida
$342K +$25.3K +88 +8%
RJFSA
99
Raymond James Financial Services Advisors
Florida
$318K +$318K +1,106 New
Russell Investments Group
100
Russell Investments Group
United Kingdom
$318K +$318K +1,107 New
2 3
4
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