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Karyopharm Therapeutics

115 hedge funds and large institutions have $482M invested in Karyopharm Therapeutics in 2018 Q4 according to their latest regulatory filings, with 15 funds opening new positions, 49 increasing their positions, 34 reducing their positions, and 17 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
115
Holders Change
-4
Holders Change %
-3.36%
% of All Funds
2.57%
Holding in Top 10
1
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
0.02%
New
15
Increased
49
Reduced
34
Closed
17
Calls
$553K
Puts
$894K
Net Calls
-$341K
Net Calls Change
+$2.08M
Name Holding Trade Value Shares
Change
Shares
Change %
ProShare Advisors
76
ProShare Advisors
Maryland
$241K -$46.5K -330 -16%
AQR Capital Management
77
AQR Capital Management
Connecticut
$240K -$48.5K -345 -17%
WMSA
78
Weiss Multi-Strategy Advisers
New York
$234K +$45.9K +327 +24%
SO
79
STRS Ohio
Ohio
$226K -$16K -114 -7%
MIM
80
MetLife Investment Management
New Jersey
$216K
VOYA Investment Management
81
VOYA Investment Management
Georgia
$197K +$21.8K +155 +12%
TRSOTSOK
82
Teachers Retirement System of the State of Kentucky
Kentucky
$175K
Man Group
83
Man Group
United Kingdom
$172K +$172K +1,227 New
Simplex Trading
84
Simplex Trading
Illinois
$169K +$156K +1,113 +1,210%
State Board of Administration of Florida Retirement System
85
State Board of Administration of Florida Retirement System
Florida
$155K +$1.41K +10 +0.9%
MLICM
86
Metropolitan Life Insurance Company (MetLife)
New York
$152K
DekaBank Deutsche Girozentrale
87
DekaBank Deutsche Girozentrale
Germany
$152K -$31.6K -227 -17%
FRM
88
Fox Run Management
Connecticut
$152K +$5.62K +40 +4%
UBS AM
89
UBS AM
Illinois
$126K +$126K +894 New
QSS
90
Quantitative Systematic Strategies
Florida
$101K +$101K +719 New
Legal & General Group
91
Legal & General Group
United Kingdom
$95K +$22.6K +160 +31%
Barclays
92
Barclays
United Kingdom
$92K -$490K -3,501 -84%
IA
93
IFP Advisors
Florida
$52K +$34.5K +250 +197%
Canada Life
94
Canada Life
Manitoba, Canada
$51K
AIP
95
Ameritas Investment Partners
Nebraska
$38K
Zurich Cantonal Bank
96
Zurich Cantonal Bank
Switzerland
$36K
PNC Financial Services Group
97
PNC Financial Services Group
Pennsylvania
$36K +$31.3K +220 +667%
IUHSA
98
Itau Unibanco Holding S.A.
Brazil
$24K +$409 +3 +2%
NIT
99
NumerixS Investment Technologies
British Columbia, Canada
$20K +$20K +147 New
TJHA
100
Thomas J. Herzfeld Advisors
Florida
$14K