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Karyopharm Therapeutics

115 hedge funds and large institutions have $482M invested in Karyopharm Therapeutics in 2018 Q4 according to their latest regulatory filings, with 15 funds opening new positions, 49 increasing their positions, 34 reducing their positions, and 17 closing their positions.

New
Increased
Maintained
Reduced
Closed

44% more repeat investments, than reductions

Existing positions increased: 49 | Existing positions reduced: 34

0.88% more ownership

Funds ownership: 4.77%5.65% (+0.88%)

0% more funds holding in top 10

Funds holding in top 10: 11 (0)

3% less funds holding

Funds holding: 119115 (-4)

12% less first-time investments, than exits

New positions opened: 15 | Existing positions closed: 17

35% less capital invested

Capital invested by funds: $738M → $482M (-$256M)

38% less call options, than puts

Call options by funds: $553K | Put options by funds: $894K

Holders
115
Holders Change
-4
Holders Change %
-3.36%
% of All Funds
2.56%
Holding in Top 10
1
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
0.02%
New
15
Increased
49
Reduced
34
Closed
17
Calls
$553K
Puts
$894K
Net Calls
-$341K
Net Calls Change
+$2.08M
Name Holding Trade Value Shares
Change
Change in
Stake
ProShare Advisors
76
ProShare Advisors
Maryland
$241K -$55.7K -330 -16%
AQR Capital Management
77
AQR Capital Management
Connecticut
$240K -$58.2K -345 -17%
WMSA
78
Weiss Multi-Strategy Advisers
New York
$234K +$55.2K +327 +24%
SO
79
STRS Ohio
Ohio
$226K -$19.2K -114 -7%
MIM
80
MetLife Investment Management
New Jersey
$216K
VOYA Investment Management
81
VOYA Investment Management
Georgia
$197K +$26.1K +155 +12%
TRSOTSOK
82
Teachers Retirement System of the State of Kentucky
Kentucky
$175K
Man Group
83
Man Group
United Kingdom
$172K +$207K +1,227 New
Simplex Trading
84
Simplex Trading
Illinois
$169K +$188K +1,113 +1,210%
State Board of Administration of Florida Retirement System
85
State Board of Administration of Florida Retirement System
Florida
$155K +$1.69K +10 +0.9%
MLICM
86
Metropolitan Life Insurance Company (MetLife)
New York
$152K
DekaBank Deutsche Girozentrale
87
DekaBank Deutsche Girozentrale
Germany
$152K -$38.3K -227 -17%
FRM
88
Fox Run Management
Connecticut
$152K +$6.75K +40 +4%
UBS AM
89
UBS AM
Illinois
$126K +$151K +894 New
QSS
90
Quantitative Systematic Strategies
Florida
$101K +$121K +719 New
Legal & General Group
91
Legal & General Group
United Kingdom
$95K +$27K +160 +31%
Barclays
92
Barclays
United Kingdom
$92K -$591K -3,501 -84%
IA
93
IFP Advisors
Florida
$52K +$42.2K +250 +197%
Canada Life
94
Canada Life
Manitoba, Canada
$51K
AIP
95
Ameritas Investment Partners
Nebraska
$38K
Zurich Cantonal Bank
96
Zurich Cantonal Bank
Switzerland
$36K
PNC Financial Services Group
97
PNC Financial Services Group
Pennsylvania
$36K +$37.1K +220 +667%
IUHSA
98
Itau Unibanco Holding S.A.
Brazil
$24K +$506 +3 +2%
NIT
99
NumerixS Investment Technologies
British Columbia, Canada
$20K +$24.8K +147 New
TJHA
100
Thomas J. Herzfeld Advisors
Florida
$14K

KPTI Hedge Fund Activity: Q4 2018 in Review

115 of the 4,489 institutional investors tracked by Wall St. Rank reported a position in Karyopharm Therapeutics (KPTI) for Q4 2018, worth a combined $482M — down 35% from $738M a quarter earlier.

Sellers outnumbered buyers: 17 funds closed out of KPTI and 15 opened new positions — a net loss of 2 holders — while 34 trimmed existing stakes and 49 added.

The largest buyer was Emerald Advisers, adding an estimated $8.57M. The largest seller was Vanguard Group, cutting an estimated $7.69M.

  • 115 institutional investors held Karyopharm Therapeutics (KPTI) as of Q4 2018, down from 119 in Q3 2018.
  • Funds reported $482M of Karyopharm Therapeutics stock for Q4 2018, down 35% quarter-over-quarter.
  • 15 funds opened new Karyopharm Therapeutics positions in Q4 2018 and 17 closed out, a net change of -2 holders.
  • The largest Karyopharm Therapeutics buyer in Q4 2018 was Emerald Advisers, an estimated $8.57M added.
  • The largest Karyopharm Therapeutics seller in Q4 2018 was Vanguard Group, an estimated $7.69M sold.

Based on aggregated 13F filings for Q4 2018.