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Karyopharm Therapeutics

85 hedge funds and large institutions have $285M invested in Karyopharm Therapeutics in 2015 Q4 according to their latest regulatory filings, with 10 funds opening new positions, 37 increasing their positions, 22 reducing their positions, and 14 closing their positions.

New
Increased
Maintained
Reduced
Closed

68% more repeat investments, than reductions

Existing positions increased: 37 | Existing positions reduced: 22

25% more call options, than puts

Call options by funds: $2.38M | Put options by funds: $1.91M

15% more capital invested

Capital invested by funds: $248M → $285M (+$37.2M)

4% less funds holding

Funds holding: 8985 (-4)

29% less first-time investments, than exits

New positions opened: 10 | Existing positions closed: 14

Holders
85
Holders Change
-4
Holders Change %
-4.49%
% of All Funds
2.23%
Holding in Top 10
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
New
10
Increased
37
Reduced
22
Closed
14
Calls
$2.38M
Puts
$1.91M
Net Calls
+$474K
Net Calls Change
-$7.02M
Name Holding Trade Value Shares
Change
Change in
Stake
PAM
76
Panagora Asset Management
Massachusetts
$24K -$6.71K -31 -20%
CLOS
77
Compagnie Lombard Odier SCmA
Switzerland
$24K
Canada Life
78
Canada Life
Manitoba, Canada
$22K
Barclays
79
Barclays
United Kingdom
$7K -$160K -738 -95%
IA
80
IFP Advisors
Florida
$7K +$7.14K +33 New
Bank of Montreal
81
Bank of Montreal
Ontario, Canada
$6K +$4.98K +23 +383%
WTB
82
Washington Trust Bank
Washington
$5K +$1.52K +7 +35%
KF
83
Krilogy Financial
Missouri
$3K
CFA
84
CT Financial Advisors
Pennsylvania
$2.65K +$2.81K +13 New
Manulife (Manufacturers Life Insurance)
85
Manulife (Manufacturers Life Insurance)
Ontario, Canada
$198 +$5.85K +27 +3%
SAM
86
Sectoral Asset Management
Quebec, Canada
-$7.51M -47,531 Closed
CAM
87
Cormorant Asset Management
Massachusetts
-$3.17M -20,066 Closed
AC
88
Ascend Capital
California
-$1.31M -8,319 Closed
PAMU
89
Pictet Asset Management (UK)
United Kingdom
-$680K -4,307 Closed
NLVP
90
New Leaf Venture Partners
New York
-$431K -2,732 Closed
UOC
91
UBS O'Connor
Illinois
-$316K -2,000 Closed
SG Americas Securities
92
SG Americas Securities
New York
-$163K -1,032 Closed
EDRH
93
Edmond de Rothschild Holding
Switzerland
-$158K -1,000 Closed
EDRS
94
Edmond de Rothschild (Suisse)
Switzerland
-$158K -1,000 Closed
TRCT
95
Tower Research Capital (TRC)
New York
-$99K -628 Closed
Goldman Sachs
96
Goldman Sachs
New York
-$47K -301 Closed
EWM
97
Edge Wealth Management
New York
-$5K -32 Closed
QT
98
Quantbot Technologies
New York
-$2K -18 Closed
NFG
99
Next Financial Group
Texas
-$1K -7 Closed

KPTI Hedge Fund Activity: Q4 2015 in Review

85 of the 3,812 institutional investors tracked by Wall St. Rank reported a position in Karyopharm Therapeutics (KPTI) for Q4 2015, worth a combined $285M — up 15% from $248M a quarter earlier.

Sellers outnumbered buyers: 14 funds closed out of KPTI and 10 opened new positions — a net loss of 4 holders — while 22 trimmed existing stakes and 37 added.

The largest buyer was Millennium Management, adding an estimated $3.88M. The largest seller was Citadel Advisors, cutting an estimated $8.02M.

  • 85 institutional investors held Karyopharm Therapeutics (KPTI) as of Q4 2015, down from 89 in Q3 2015.
  • Funds reported $285M of Karyopharm Therapeutics stock for Q4 2015, up 15% quarter-over-quarter.
  • 10 funds opened new Karyopharm Therapeutics positions in Q4 2015 and 14 closed out, a net change of -4 holders.
  • The largest Karyopharm Therapeutics buyer in Q4 2015 was Millennium Management, an estimated $3.88M added.
  • The largest Karyopharm Therapeutics seller in Q4 2015 was Citadel Advisors, an estimated $8.02M sold.

Based on aggregated 13F filings for Q4 2015.