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Karyopharm Therapeutics

168 hedge funds and large institutions have $987M invested in Karyopharm Therapeutics in 2020 Q4 according to their latest regulatory filings, with 32 funds opening new positions, 61 increasing their positions, 44 reducing their positions, and 21 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
168
Holders Change
Holders Change %
% of All Funds
Holding in Top 10
2
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
New
Increased
Reduced
Closed
Calls
$11.2M
Puts
$7.99M
Net Calls
Net Calls Change

Top Buyers

1 +$36.1M
2 +$12.9M
3 +$9.29M
4
State Street
State Street
Massachusetts
+$8.53M
5
Alkeon Capital Management
Alkeon Capital Management
New York
+$7.76M

Top Sellers

1 -$87.6M
2 -$19.3M
3 -$15.6M
4
Adage Capital Partners
Adage Capital Partners
Massachusetts
-$11.6M
5
Two Sigma Advisers
Two Sigma Advisers
New York
-$10.5M
Name Holding Trade Value Shares
Change
Change in
Stake
51
$2.01M
52
$1.93M
53
$1.8M
54
$1.64M
55
$1.55M
56
$1.55M
57
$1.47M
58
$1.41M
59
$1.31M
60
$1.25M
61
$1.24M
62
$1.24M
63
$1.22M
64
$1.16M
65
$1.13M
66
$1.11M
67
$1.1M
68
$1.1M
69
$1.06M
70
$1.02M
71
$973K
72
$953K
73
$912K
74
$888K
75
$864K