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Karyopharm Therapeutics

168 hedge funds and large institutions have $987M invested in Karyopharm Therapeutics in 2020 Q4 according to their latest regulatory filings, with 32 funds opening new positions, 61 increasing their positions, 44 reducing their positions, and 21 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
168
Holders Change
Holders Change %
% of All Funds
Holding in Top 10
2
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
New
Increased
Reduced
Closed
Calls
$11.2M
Puts
$7.99M
Net Calls
Net Calls Change

Top Buyers

1 +$36.1M
2 +$12.9M
3 +$9.29M
4
State Street
State Street
Massachusetts
+$8.53M
5
Alkeon Capital Management
Alkeon Capital Management
New York
+$7.76M

Top Sellers

1 -$87.6M
2 -$19.3M
3 -$15.6M
4
Adage Capital Partners
Adage Capital Partners
Massachusetts
-$11.6M
5
Two Sigma Advisers
Two Sigma Advisers
New York
-$10.5M
Name Holding Trade Value Shares
Change
Change in
Stake
26
$7.85M
27
$7.78M
28
$7.23M
29
$6.21M
30
$5.9M
31
$5.61M
32
$5.53M
33
$5.19M
34
$5.09M
35
$4.75M
36
$4.29M
37
$4.05M
38
$3.57M
39
$3.37M
40
$3.31M
41
$2.91M
42
$2.63M
43
$2.58M
44
$2.49M
45
$2.49M
46
$2.42M
47
$2.27M
48
$2.18M
49
$2.1M
50
$2.07M