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Karyopharm Therapeutics

146 hedge funds and large institutions have $1.13B invested in Karyopharm Therapeutics in 2019 Q4 according to their latest regulatory filings, with 52 funds opening new positions, 41 increasing their positions, 39 reducing their positions, and 11 closing their positions.

New
Increased
Maintained
Reduced
Closed

400% more funds holding in top 10

Funds holding in top 10: 15 (+4)

373% more first-time investments, than exits

New positions opened: 52 | Existing positions closed: 11

101% more capital invested

Capital invested by funds: $563M → $1.13B (+$567M)

38% more funds holding

Funds holding: 106146 (+40)

5% more call options, than puts

Call options by funds: $16.5M | Put options by funds: $15.6M

5% more repeat investments, than reductions

Existing positions increased: 41 | Existing positions reduced: 39

0.04% less ownership

Funds ownership: 6.3%6.26% (-0.04%)

Holders
146
Holders Change
+40
Holders Change %
+37.74%
% of All Funds
2.88%
Holding in Top 10
5
Holding in Top 10 Change
+4
Holding in Top 10 Change %
+400%
% of All Funds
0.1%
New
52
Increased
41
Reduced
39
Closed
11
Calls
$16.5M
Puts
$15.6M
Net Calls
+$838K
Net Calls Change
+$955K
Name Holding Trade Value Shares
Change
Change in
Stake
PHP
26
Parkman Healthcare Partners
Connecticut
$9.59M +$7.23M +33,333 New
EMFAT
27
Emerald Mutual Fund Advisers Trust
Pennsylvania
$9.32M -$13.7M -63,120 -66%
N
28
Nuveen
North Carolina
$8.86M +$923K +4,255 +16%
ECP
29
Elk Creek Partners
Colorado
$8.82M -$11.7M -54,028 -64%
FFM
30
Fairmount Funds Management
Pennsylvania
$7.7M +$5.81M +26,774 New
Macquarie Group
31
Macquarie Group
Australia
$7.29M
JP Morgan Chase
32
JP Morgan Chase
New York
$6.85M +$2.06M +9,518 +66%
Charles Schwab
33
Charles Schwab
California
$6.72M +$92.6K +427 +2%
IHAM
34
Integral Health Asset Management
New York
$6.61M +$4.99M +23,000 New
SFM
35
Sphera Funds Management
Israel
$6.33M +$4.77M +22,000 New
AI
36
Atom Investors
Texas
$6.29M -$1.12M -5,166 -19%
California Public Employees Retirement System
37
California Public Employees Retirement System
California
$5.85M +$1.79M +8,229 +68%
Marshall Wace
38
Marshall Wace
United Kingdom
$5.64M +$4.26M +19,634 New
Bank of New York Mellon
39
Bank of New York Mellon
New York
$5.58M +$735K +3,387 +21%
Invesco
40
Invesco
Georgia
$4.5M -$647K -2,983 -16%
MOACM
41
Mutual of America Capital Management
New York
$4.26M -$22.1K -102 -0.7%
EI
42
EAM Investors
California
$3.39M +$2.56M +11,778 New
T. Rowe Price Associates
43
T. Rowe Price Associates
Maryland
$3.25M +$2.46M +11,317 New
Renaissance Technologies
44
Renaissance Technologies
New York
$3.08M +$2.32M +10,700 New
QI
45
QS Investors
New York
$2.74M +$2.12M +9,753 New
Jacobs Levy Equity Management
46
Jacobs Levy Equity Management
New Jersey
$2.54M +$864K +3,981 +82%
LCG
47
Lisanti Capital Growth
New York
$2.43M +$1.83M +8,450 New
Alkeon Capital Management
48
Alkeon Capital Management
New York
$2.4M +$1.81M +8,333 New
RhumbLine Advisers
49
RhumbLine Advisers
Massachusetts
$2.37M +$113K +521 +7%
EGI
50
EAM Global Investors
California
$2.34M +$1.76M +8,134 New

KPTI Hedge Fund Activity: Q4 2019 in Review

146 of the 5,076 institutional investors tracked by Wall St. Rank reported a position in Karyopharm Therapeutics (KPTI) for Q4 2019, worth a combined $1.13B — up 101% from $563M a quarter earlier.

Buyers outnumbered sellers: 52 funds opened new KPTI positions and 11 closed out — a net gain of 41 holders — while 41 added to existing stakes and 39 trimmed.

The largest buyer was Adage Capital Partners, adding an estimated $30.2M. The largest seller was Wellington Management Group, cutting an estimated $63.6M.

  • 146 institutional investors held Karyopharm Therapeutics (KPTI) as of Q4 2019, up from 106 in Q3 2019.
  • Funds reported $1.13B of Karyopharm Therapeutics stock for Q4 2019, up 101% quarter-over-quarter.
  • 52 funds opened new Karyopharm Therapeutics positions in Q4 2019 and 11 closed out, a net change of +41 holders.
  • The largest Karyopharm Therapeutics buyer in Q4 2019 was Adage Capital Partners, an estimated $30.2M added.
  • The largest Karyopharm Therapeutics seller in Q4 2019 was Wellington Management Group, an estimated $63.6M sold.

Based on aggregated 13F filings for Q4 2019.