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Karyopharm Therapeutics
KPTI

Overview Fund Activity

146 hedge funds and large institutions have $1.13B invested in Karyopharm Therapeutics in 2019 Q4 according to their latest regulatory filings, with 52 funds opening new positions, 41 increasing their positions, 39 reducing their positions, and 11 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
146
Holders Change
+40
Holders Change %
+37.74%
% of All Funds
2.88%
Holding in Top 10
5
Holding in Top 10 Change
+4
Holding in Top 10 Change %
+400%
% of All Funds
0.1%
New
52
Increased
41
Reduced
39
Closed
11
Calls
$16.5M
Puts
$15.6M
Net Calls
+$838K
Net Calls Change
+$955K

Top Buyers

1
Adage Capital Partners
Adage Capital Partners
Massachusetts
+$40M
2
D.E. Shaw & Co
D.E. Shaw & Co
New York
+$18.9M
3
Federated Hermes
Federated Hermes
Pennsylvania
+$15.7M
4
Two Sigma Investments
Two Sigma Investments
New York
+$14M
5
ACP
Acuta Capital Partners
California
+$6.76M

Top Sellers

1
Wellington Management Group
Wellington Management Group
Massachusetts
-$84.3M
2
Millennium Management
Millennium Management
New York
-$24.4M
3
EA
Emerald Advisers
Pennsylvania
-$19.1M
4
EMFAT
Emerald Mutual Fund Advisers Trust
Pennsylvania
-$18.1M
5
ECP
Elk Creek Partners
Colorado
-$15.5M
Name Holding Trade Value Shares
Change 		Shares
Change %
PHP
26
Parkman Healthcare Partners
Connecticut
$9.59M +$9.59M +33,333 New
EMFAT
27
Emerald Mutual Fund Advisers Trust
Pennsylvania
$9.32M -$18.1M -63,120 -66%
Nuveen Asset Management
28
Nuveen Asset Management
Illinois
$8.86M +$1.22M +4,255 +16%
ECP
29
Elk Creek Partners
Colorado
$8.82M -$15.5M -54,028 -64%
FFM
30
Fairmount Funds Management
Pennsylvania
$7.7M +$7.7M +26,774 New
Macquarie Group
31
Macquarie Group
Australia
$7.29M – – –
JPMorgan Chase & Co
32
JPMorgan Chase & Co
New York
$6.85M +$2.74M +9,518 +66%
Charles Schwab
33
Charles Schwab
California
$6.72M +$123K +427 +2%
IHAM
34
Integral Health Asset Management
New York
$6.61M +$6.61M +23,000 New
SFM
35
Sphera Funds Management
Israel
$6.33M +$6.33M +22,000 New
AI
36
Atom Investors
Texas
$6.29M -$1.49M -5,166 -19%
California Public Employees Retirement System
37
California Public Employees Retirement System
California
$5.85M +$2.37M +8,229 +68%
Marshall Wace
38
Marshall Wace
United Kingdom
$5.65M +$5.65M +19,634 New
Bank of New York Mellon
39
Bank of New York Mellon
New York
$5.58M +$974K +3,387 +21%
Invesco
40
Invesco
Georgia
$4.5M -$858K -2,983 -16%
MOACM
41
Mutual of America Capital Management
New York
$4.26M -$29.3K -102 -0.7%
EI
42
EAM Investors
California
$3.39M +$3.39M +11,778 New
T. Rowe Price Associates
43
T. Rowe Price Associates
Maryland
$3.25M +$3.25M +11,317 New
Renaissance Technologies
44
Renaissance Technologies
New York
$3.08M +$3.08M +10,700 New
QI
45
QS Investors
New York
$2.74M +$2.74M +9,753 New
Jacobs Levy Equity Management
46
Jacobs Levy Equity Management
New Jersey
$2.54M +$1.14M +3,981 +82%
LCG
47
Lisanti Capital Growth
New York
$2.43M +$2.43M +8,450 New
Alkeon Capital Management
48
Alkeon Capital Management
New York
$2.4M +$2.4M +8,333 New
RhumbLine Advisers
49
RhumbLine Advisers
Massachusetts
$2.37M +$150K +521 +7%
EGI
50
EAM Global Investors
California
$2.34M +$2.34M +8,134 New
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