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Karyopharm Therapeutics

103 hedge funds and large institutions have $306M invested in Karyopharm Therapeutics in 2019 Q2 according to their latest regulatory filings, with 17 funds opening new positions, 39 increasing their positions, 30 reducing their positions, and 18 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
103
Holders Change
-5
Holders Change %
-4.63%
% of All Funds
2.24%
Holding in Top 10
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
New
17
Increased
39
Reduced
30
Closed
18
Calls
$4.59M
Puts
$815K
Net Calls
+$3.77M
Net Calls Change
+$990K
Name Holding Trade Value Shares
Change
Shares
Change %
Two Sigma Advisers
26
Two Sigma Advisers
New York
$1.78M -$445K -4,954 -20%
Bank of New York Mellon
27
Bank of New York Mellon
New York
$1.39M +$75.9K +844 +6%
MOACM
28
Mutual of America Capital Management
New York
$1.35M +$899 +10 +0.1%
JPMorgan Chase & Co
29
JPMorgan Chase & Co
New York
$1.26M -$20K -218 -2%
Goldman Sachs
30
Goldman Sachs
New York
$993K +$13.2K +147 +1%
California Public Employees Retirement System
31
California Public Employees Retirement System
California
$959K -$33.9K -377 -3%
AllianceBernstein
32
AllianceBernstein
Tennessee
$714K +$171K +1,907 +32%
RhumbLine Advisers
33
RhumbLine Advisers
Massachusetts
$692K -$102K -1,139 -13%
Morgan Stanley
34
Morgan Stanley
New York
$690K -$294K -3,276 -30%
USAA
35
United Services Automobile Association
Texas
$652K +$5.57K +62 +0.9%
ARTA
36
A.R.T. Advisors
New York
$617K +$531K +5,901 +614%
CS
37
Credit Suisse
Switzerland
$572K -$45.8K -511 -7%
Swiss National Bank
38
Swiss National Bank
Switzerland
$542K +$32.3K +360 +6%
California State Teachers Retirement System (CalSTRS)
39
California State Teachers Retirement System (CalSTRS)
California
$533K +$77.9K +866 +17%
SIM
40
Spark Investment Management
New York
$520K -$1.08M -12,056 -68%
Deutsche Bank
41
Deutsche Bank
Germany
$511K -$4.91M -54,888 -91%
CSS
42
Cubist Systematic Strategies
Connecticut
$506K +$399K +4,441 +372%
Renaissance Technologies
43
Renaissance Technologies
New York
$440K -$5.06M -56,352 -92%
Millennium Management
44
Millennium Management
New York
$435K -$15.8M -176,470 -97%
BC
45
Birchview Capital
Vermont
$419K
State of Wisconsin Investment Board
46
State of Wisconsin Investment Board
Wisconsin
$398K +$8.99K +100 +2%
Susquehanna International Group
47
Susquehanna International Group
Pennsylvania
$373K -$2.97M -33,049 -89%
Two Sigma Investments
48
Two Sigma Investments
New York
$371K -$1.71M -18,992 -82%
Wells Fargo
49
Wells Fargo
California
$361K +$28.5K +318 +9%
Connor, Clark & Lunn Investment Management (CC&L)
50
Connor, Clark & Lunn Investment Management (CC&L)
British Columbia, Canada
$346K -$440K -4,885 -56%