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Karyopharm Therapeutics

103 hedge funds and large institutions have $306M invested in Karyopharm Therapeutics in 2019 Q2 according to their latest regulatory filings, with 17 funds opening new positions, 39 increasing their positions, 30 reducing their positions, and 18 closing their positions.

New
Increased
Maintained
Reduced
Closed

463% more call options, than puts

Call options by funds: $4.58M | Put options by funds: $815K

30% more repeat investments, than reductions

Existing positions increased: 39 | Existing positions reduced: 30

2% more capital invested

Capital invested by funds: $300M → $306M (+$6.39M)

0.01% less ownership

Funds ownership: 5.61%5.6% (-0.01%)

6% less first-time investments, than exits

New positions opened: 17 | Existing positions closed: 18

5% less funds holding

Funds holding: 108103 (-5)

Holders
103
Holders Change
-5
Holders Change %
-4.63%
% of All Funds
2.24%
Holding in Top 10
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
New
17
Increased
39
Reduced
30
Closed
18
Calls
$4.58M
Puts
$815K
Net Calls
+$3.77M
Net Calls Change
+$990K
Name Holding Trade Value Shares
Change
Change in
Stake
Two Sigma Advisers
26
Two Sigma Advisers
New York
$1.77M -$398K -4,954 -20%
Bank of New York Mellon
27
Bank of New York Mellon
New York
$1.39M +$67.8K +844 +6%
MOACM
28
Mutual of America Capital Management
New York
$1.35M +$803 +10 +0.1%
JP Morgan Chase
29
JP Morgan Chase
New York
$1.26M -$17.5K -218 -2%
Goldman Sachs
30
Goldman Sachs
New York
$993K +$11.8K +147 +1%
California Public Employees Retirement System
31
California Public Employees Retirement System
California
$959K -$30.3K -377 -3%
AllianceBernstein
32
AllianceBernstein
Tennessee
$714K +$153K +1,907 +32%
RhumbLine Advisers
33
RhumbLine Advisers
Massachusetts
$692K -$91.5K -1,139 -13%
Morgan Stanley
34
Morgan Stanley
New York
$690K -$263K -3,276 -30%
USAA
35
United Services Automobile Association
Texas
$652K +$4.98K +62 +0.9%
ARTA
36
A.R.T. Advisors
New York
$617K +$474K +5,901 +614%
CS
37
Credit Suisse
Switzerland
$572K -$41K -511 -7%
Swiss National Bank
38
Swiss National Bank
Switzerland
$542K +$28.9K +360 +6%
California State Teachers Retirement System (CalSTRS)
39
California State Teachers Retirement System (CalSTRS)
California
$533K +$69.5K +866 +17%
SIM
40
Spark Investment Management
New York
$520K -$968K -12,056 -68%
Deutsche Bank
41
Deutsche Bank
Germany
$511K -$4.41M -54,888 -91%
CSS
42
Cubist Systematic Strategies
Connecticut
$506K +$357K +4,441 +372%
Renaissance Technologies
43
Renaissance Technologies
New York
$440K -$4.52M -56,352 -92%
Millennium Management
44
Millennium Management
New York
$435K -$14.2M -176,470 -97%
BC
45
Birchview Capital
Vermont
$419K
State of Wisconsin Investment Board
46
State of Wisconsin Investment Board
Wisconsin
$398K +$8.03K +100 +2%
Susquehanna International Group
47
Susquehanna International Group
Pennsylvania
$373K -$2.65M -33,049 -89%
Two Sigma Investments
48
Two Sigma Investments
New York
$371K -$1.52M -18,992 -82%
Wells Fargo
49
Wells Fargo
California
$361K +$25.5K +318 +9%
Connor, Clark & Lunn Investment Management (CC&L)
50
Connor, Clark & Lunn Investment Management (CC&L)
British Columbia, Canada
$346K -$392K -4,885 -56%

KPTI Hedge Fund Activity: Q2 2019 in Review

103 of the 4,605 institutional investors tracked by Wall St. Rank reported a position in Karyopharm Therapeutics (KPTI) for Q2 2019, worth a combined $306M — up 2.1% from $300M a quarter earlier.

Sellers outnumbered buyers: 18 funds closed out of KPTI and 17 opened new positions — a net loss of 1 holder — while 30 trimmed existing stakes and 39 added.

The largest buyer was OrbiMed, opening a new position worth an estimated $16.9M. The largest seller was Millennium Management, cutting an estimated $14.2M.

  • 103 institutional investors held Karyopharm Therapeutics (KPTI) as of Q2 2019, down from 108 in Q1 2019.
  • Funds reported $306M of Karyopharm Therapeutics stock for Q2 2019, up 2.1% quarter-over-quarter.
  • 17 funds opened new Karyopharm Therapeutics positions in Q2 2019 and 18 closed out, a net change of -1 holder.
  • The largest Karyopharm Therapeutics buyer in Q2 2019 was OrbiMed, an estimated $16.9M added.
  • The largest Karyopharm Therapeutics seller in Q2 2019 was Millennium Management, an estimated $14.2M sold.

Based on aggregated 13F filings for Q2 2019.