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Karyopharm Therapeutics

108 hedge funds and large institutions have $300M invested in Karyopharm Therapeutics in 2019 Q1 according to their latest regulatory filings, with 19 funds opening new positions, 42 increasing their positions, 21 reducing their positions, and 26 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
108
Holders Change
-7
Holders Change %
-6.09%
% of All Funds
2.34%
Holding in Top 10
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-100%
% of All Funds
New
19
Increased
42
Reduced
21
Closed
26
Calls
$4.08M
Puts
$1.3M
Net Calls
+$2.78M
Net Calls Change
+$3.12M
Name Holding Trade Value Shares
Change
Shares
Change %
Two Sigma Advisers
26
Two Sigma Advisers
New York
$2.16M +$801K +9,140 +59%
Two Sigma Investments
27
Two Sigma Investments
New York
$2.03M -$1.54M -17,625 -43%
HM
28
HealthCor Management
New York
$1.73M +$1.73M +19,742 New
SIM
29
Spark Investment Management
New York
$1.56M +$548K +6,262 +54%
Charles Schwab
30
Charles Schwab
California
$1.48M -$86.6K -988 -6%
CIA
31
Capital Impact Advisors
Massachusetts
$1.4M
TCIM
32
TIAA CREF Investment Management
New York
$1.39M -$841K -9,605 -38%
MOACM
33
Mutual of America Capital Management
New York
$1.31M +$523K +5,969 +66%
Bank of New York Mellon
34
Bank of New York Mellon
New York
$1.28M +$3.33K +38 +0.3%
JPMorgan Chase & Co
35
JPMorgan Chase & Co
New York
$1.22M +$532K +6,070 +78%
BFM
36
Boothbay Fund Management
New York
$1.05M +$1.05M +12,024 New
California Public Employees Retirement System
37
California Public Employees Retirement System
California
$968K
Morgan Stanley
38
Morgan Stanley
New York
$960K +$458K +5,230 +91%
Goldman Sachs
39
Goldman Sachs
New York
$955K +$15.4K +176 +2%
RhumbLine Advisers
40
RhumbLine Advisers
Massachusetts
$774K +$226K +2,582 +41%
Connor, Clark & Lunn Investment Management (CC&L)
41
Connor, Clark & Lunn Investment Management (CC&L)
British Columbia, Canada
$765K +$765K +8,730 New
MWNA
42
Marshall Wace North America
New York
$663K +$663K +7,572 New
USAA
43
United Services Automobile Association
Texas
$630K
SSA
44
Schonfeld Strategic Advisors
New York
$612K -$105K -1,200 -15%
CS
45
Credit Suisse
Switzerland
$603K +$218K +2,488 +57%
MCM
46
Moore Capital Management
New York
$584K
PVI
47
Pura Vida Investments
New York
$584K +$584K +6,667 New
Federated Hermes
48
Federated Hermes
Pennsylvania
$536K -$1.18M -13,441 -69%
AllianceBernstein
49
AllianceBernstein
Tennessee
$529K +$154K +1,760 +41%
Prudential Financial
50
Prudential Financial
New Jersey
$517K +$87.6K +1,000 +20%