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Karyopharm Therapeutics

88 hedge funds and large institutions have $415M invested in Karyopharm Therapeutics in 2018 Q1 according to their latest regulatory filings, with 13 funds opening new positions, 39 increasing their positions, 21 reducing their positions, and 14 closing their positions.

New
Increased
Maintained
Reduced
Closed

86% more repeat investments, than reductions

Existing positions increased: 39 | Existing positions reduced: 21

39% more capital invested

Capital invested by funds: $298M → $415M (+$117M)

0.23% less ownership

Funds ownership: 4.38%4.15% (-0.23%)

2% less call options, than puts

Call options by funds: $2.65M | Put options by funds: $2.7M

7% less first-time investments, than exits

New positions opened: 13 | Existing positions closed: 14

2% less funds holding

Funds holding: 9088 (-2)

Holders
88
Holders Change
-2
Holders Change %
-2.22%
% of All Funds
2.02%
Holding in Top 10
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
New
13
Increased
39
Reduced
21
Closed
14
Calls
$2.65M
Puts
$2.7M
Net Calls
-$54K
Net Calls Change
-$1M
Name Holding Trade Value Shares
Change
Change in
Stake
Morgan Stanley
26
Morgan Stanley
New York
$1.98M +$1.03M +5,179 +111%
IHM
27
Iguana Healthcare Management
New York
$1.68M -$2.33M -11,667 -58%
Two Sigma Investments
28
Two Sigma Investments
New York
$1.64M +$1.3M +6,511 +403%
Goldman Sachs
29
Goldman Sachs
New York
$1.5M +$444K +2,229 +43%
Citadel Advisors
30
Citadel Advisors
Florida
$1.26M +$527K +2,642 +73%
KCM
31
Kennedy Capital Management
Missouri
$1.24M +$1.23M +6,181 New
USAA
32
United Services Automobile Association
Texas
$1.16M +$62.4K +313 +6%
VEA
33
Virtus ETF Advisers
New York
$1.09M +$590K +2,957 +120%
GTC
34
Ghost Tree Capital
New York
$1.03M +$1.02M +5,119 New
AllianceBernstein
35
AllianceBernstein
Tennessee
$975K -$609K -3,053 -39%
Prudential Financial
36
Prudential Financial
New Jersey
$923K +$659K +3,307 +259%
Swiss National Bank
37
Swiss National Bank
Switzerland
$861K +$97.1K +487 +13%
California State Teachers Retirement System (CalSTRS)
38
California State Teachers Retirement System (CalSTRS)
California
$726K +$11K +55 +2%
Jacobs Levy Equity Management
39
Jacobs Levy Equity Management
New Jersey
$698K -$16K -80 -2%
OPPM
40
Opus Point Partners Management
New York
$671K -$665K -3,334 -50%
CS
41
Credit Suisse
Switzerland
$619K +$80.4K +403 +15%
Bank of America
42
Bank of America
North Carolina
$602K +$31.1K +156 +5%
TG
43
TCW Group
California
$583K +$37.3K +187 +7%
Barclays
44
Barclays
United Kingdom
$577K +$192K +964 +51%
New York State Common Retirement Fund
45
New York State Common Retirement Fund
New York
$506K +$95.7K +480 +24%
Wells Fargo
46
Wells Fargo
California
$483K +$67.2K +337 +16%
RhumbLine Advisers
47
RhumbLine Advisers
Massachusetts
$450K +$13K +65 +3%
TI
48
Trexquant Investment
Connecticut
$416K +$412K +2,068 New
ProShare Advisors
49
ProShare Advisors
Maryland
$368K -$39.9K -200 -10%
State of Wisconsin Investment Board
50
State of Wisconsin Investment Board
Wisconsin
$349K

KPTI Hedge Fund Activity: Q1 2018 in Review

88 of the 4,364 institutional investors tracked by Wall St. Rank reported a position in Karyopharm Therapeutics (KPTI) for Q1 2018, worth a combined $415M — up 39% from $298M a quarter earlier.

Sellers outnumbered buyers: 14 funds closed out of KPTI and 13 opened new positions — a net loss of 1 holder — while 21 trimmed existing stakes and 39 added.

The largest buyer was Millennium Management, adding an estimated $11.1M. The largest seller was Point72 Asset Management, cutting an estimated $18.5M.

  • 88 institutional investors held Karyopharm Therapeutics (KPTI) as of Q1 2018, down from 90 in Q4 2017.
  • Funds reported $415M of Karyopharm Therapeutics stock for Q1 2018, up 39% quarter-over-quarter.
  • 13 funds opened new Karyopharm Therapeutics positions in Q1 2018 and 14 closed out, a net change of -1 holder.
  • The largest Karyopharm Therapeutics buyer in Q1 2018 was Millennium Management, an estimated $11.1M added.
  • The largest Karyopharm Therapeutics seller in Q1 2018 was Point72 Asset Management, an estimated $18.5M sold.

Based on aggregated 13F filings for Q1 2018.