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Karyopharm Therapeutics

89 hedge funds and large institutions have $248M invested in Karyopharm Therapeutics in 2015 Q3 according to their latest regulatory filings, with 13 funds opening new positions, 37 increasing their positions, 25 reducing their positions, and 13 closing their positions.

New
Increased
Maintained
Reduced
Closed

330% more call options, than puts

Call options by funds: $9.77M | Put options by funds: $2.27M

48% more repeat investments, than reductions

Existing positions increased: 37 | Existing positions reduced: 25

0% more funds holding

Funds holding: 8989 (0)

0% more first-time investments, than exits

New positions opened: 13 | Existing positions closed: 13

59% less capital invested

Capital invested by funds: $610M → $248M (-$362M)

100% less funds holding in top 10

Funds holding in top 10: 10 (-1)

Holders
89
Holders Change
Holders Change %
0%
% of All Funds
2.48%
Holding in Top 10
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-100%
% of All Funds
New
13
Increased
37
Reduced
25
Closed
13
Calls
$9.77M
Puts
$2.27M
Net Calls
+$7.5M
Net Calls Change
+$8.8M
Name Holding Trade Value Shares
Change
Change in
Stake
New York State Common Retirement Fund
26
New York State Common Retirement Fund
New York
$855K +$161K +602 +13%
JP Morgan Chase
27
JP Morgan Chase
New York
$846K -$64.7K -242 -4%
BIM
28
BlackRock Investment Management
Delaware
$839K -$346K -1,294 -20%
Bank of America
29
Bank of America
North Carolina
$809K -$866K -3,238 -39%
TCIM
30
TIAA CREF Investment Management
New York
$802K -$11.8K -44 -0.9%
Susquehanna International Group
31
Susquehanna International Group
Pennsylvania
$713K +$587K +2,196 +95%
PAMU
32
Pictet Asset Management (UK)
United Kingdom
$680K
Charles Schwab
33
Charles Schwab
California
$603K -$65.8K -246 -6%
MOACM
34
Mutual of America Capital Management
New York
$578K +$275K +1,030 +39%
D.E. Shaw & Co
35
D.E. Shaw & Co
New York
$513K +$868K +3,247 New
TG
36
TCW Group
California
$447K -$357K -1,334 -32%
California State Teachers Retirement System (CalSTRS)
37
California State Teachers Retirement System (CalSTRS)
California
$443K -$1.87K -7 -0.2%
NLVP
38
New Leaf Venture Partners
New York
$431K -$1.53M -5,714 -68%
Connor, Clark & Lunn Investment Management (CC&L)
39
Connor, Clark & Lunn Investment Management (CC&L)
British Columbia, Canada
$422K -$100K -375 -12%
AllianceBernstein
40
AllianceBernstein
Tennessee
$390K -$9.74M -36,437 -94%
TA
41
Teachers Advisors
New York
$355K -$938K -3,508 -61%
HCM
42
Highbridge Capital Management
New York
$354K +$600K +2,242 New
TAM
43
Tocqueville Asset Management
New York
$316K +$4.55K +17 +0.9%
UOC
44
UBS O'Connor
Illinois
$316K +$535K +2,000 New
ProShare Advisors
45
ProShare Advisors
Maryland
$310K -$35.6K -133 -6%
Swiss National Bank
46
Swiss National Bank
Switzerland
$294K +$35.6K +133 +8%
RhumbLine Advisers
47
RhumbLine Advisers
Massachusetts
$218K +$21.7K +81 +6%
DekaBank Deutsche Girozentrale
48
DekaBank Deutsche Girozentrale
Germany
$190K +$12.6K +47 +4%
Balyasny Asset Management
49
Balyasny Asset Management
Illinois
$180K +$305K +1,140 New
MLICM
50
Metropolitan Life Insurance Company (MetLife)
New York
$178K

KPTI Hedge Fund Activity: Q3 2015 in Review

89 of the 3,582 institutional investors tracked by Wall St. Rank reported a position in Karyopharm Therapeutics (KPTI) for Q3 2015, worth a combined $248M — down 59% from $610M a quarter earlier.

Fund positioning in KPTI was balanced in Q3 2015: 13 funds opened new positions, 13 closed out, 37 added to existing stakes and 25 trimmed.

The largest buyer was Palo Alto Investors, adding an estimated $24.1M. The largest seller was PFM Health Sciences, exiting entirely with an estimated $22.4M sold.

  • 89 institutional investors held Karyopharm Therapeutics (KPTI) as of Q3 2015, unchanged from Q2 2015.
  • Funds reported $248M of Karyopharm Therapeutics stock for Q3 2015, down 59% quarter-over-quarter.
  • 13 funds opened new Karyopharm Therapeutics positions in Q3 2015 and 13 closed out, a net change of 0 holders.
  • The largest Karyopharm Therapeutics buyer in Q3 2015 was Palo Alto Investors, an estimated $24.1M added.
  • The largest Karyopharm Therapeutics seller in Q3 2015 was PFM Health Sciences, an estimated $22.4M sold.

Based on aggregated 13F filings for Q3 2015.