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Karyopharm Therapeutics
KPTI

81 hedge funds and large institutions have $701M invested in Karyopharm Therapeutics in 2014 Q4 according to their latest regulatory filings, with 19 funds opening new positions, 29 increasing their positions, 19 reducing their positions, and 8 closing their positions.

New
Increased
Maintained
Reduced
Closed

138% more first-time investments, than exits

New positions opened: 19 | Existing positions closed: 8

53% more repeat investments, than reductions

Existing positions increased: 29 | Existing positions reduced: 19

19% more capital invested

Capital invested by funds: $587M → $701M (+$114M)

14% more funds holding

Funds holding: 71 → 81 (+10)

0% more funds holding in top 10

Funds holding in top 10: 2 → 2 (0)

19% less call options, than puts

Call options by funds: $1.34M | Put options by funds: $1.65M

Holders
81
Holders Change
+10
Holders Change %
+14.08%
% of All Funds
2.16%
Holding in Top 10
2
Holding in Top 10 Change
–
Holding in Top 10 Change %
–
% of All Funds
0.05%
New
19
Increased
29
Reduced
19
Closed
8
Calls
$1.34M
Puts
$1.65M
Net Calls
-$306K
Net Calls Change
-$90K

Top Buyers

Rank Fund Capital Flow
1
Fidelity Investments
Fidelity Investments
Massachusetts
+$32M
2
BFA
BlackRock Fund Advisors
California
+$16.8M
3
Franklin Resources
Franklin Resources
California
+$8.81M
4
State Street
State Street
Massachusetts
+$4.07M
5
UBS AM
UBS AM
Illinois
+$3.95M

Top Sellers

Rank Fund Capital Flow
1
PHS
PFM Health Sciences
California
-$10.4M
2
BA
BlackRock Advisors
Delaware
-$4.43M
3
Wellington Management Group
Wellington Management Group
Massachusetts
-$4.23M
4
Lord, Abbett & Co
Lord, Abbett & Co
New Jersey
-$3.69M
5
Balyasny Asset Management
Balyasny Asset Management
Illinois
-$3.48M
Name Holding Trade Value Shares
Change 		Change in
Stake
BlackRock
26
BlackRock
New York
$3.12M -$731K -1,287 -19%
DCM
27
Driehaus Capital Management
Illinois
$3.03M +$82.9K +146 +3%
Geode Capital Management
28
Geode Capital Management
Massachusetts
$2.89M -$13.1K -23 -0.4%
TA
29
Teachers Advisors
New York
$2.63M -$3.41K -6 -0.1%
BIM
30
BlackRock Investment Management
Delaware
$2.6M -$15.3K -27 -0.6%
Lord, Abbett & Co
31
Lord, Abbett & Co
New Jersey
$2.59M -$3.69M -6,504 -58%
Bank of New York Mellon
32
Bank of New York Mellon
New York
$2.36M +$5.68K +10 +0.2%
Millennium Management
33
Millennium Management
New York
$1.87M +$1.89M +3,333 New
JP Morgan Chase
34
JP Morgan Chase
New York
$1.86M -$180K -317 -9%
TCIM
35
TIAA CREF Investment Management
New York
$1.8M +$54.5K +96 +3%
Morgan Stanley
36
Morgan Stanley
New York
$1.79M -$27.8K -49 -2%
PAMU
37
Pictet Asset Management (UK)
United Kingdom
$1.72M +$405K +713 +30%
Goldman Sachs
38
Goldman Sachs
New York
$1.64M +$1.29M +2,277 +357%
MOACM
39
Mutual of America Capital Management
New York
$1.52M +$24.4K +43 +2%
Bank of America
40
Bank of America
North Carolina
$1.45M +$834K +1,469 +132%
Charles Schwab
41
Charles Schwab
California
$1.16M +$11.9K +21 +1%
EAM
42
Eventide Asset Management
Massachusetts
$1.12M – – –
California State Teachers Retirement System (CalSTRS)
43
California State Teachers Retirement System (CalSTRS)
California
$941K +$3.98K +7 +0.4%
ProShare Advisors
44
ProShare Advisors
Maryland
$920K +$930K +1,638 New
Swiss National Bank
45
Swiss National Bank
Switzerland
$734K – – –
CS
46
Credit Suisse
Switzerland
$685K +$398K +700 +134%
WC
47
Woodstock Corp
Massachusetts
$655K +$663K +1,167 New
PIM
48
Partner Investment Management
California
$614K -$195K -344 -24%
Susquehanna International Group
49
Susquehanna International Group
Pennsylvania
$544K +$550K +968 New
AQR Capital Management
50
AQR Capital Management
Connecticut
$453K +$458K +807 New
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KPTI Hedge Fund Activity: Q4 2014 in Review

81 of the 3,751 institutional investors tracked by Wall St. Rank reported a position in Karyopharm Therapeutics (KPTI) for Q4 2014, worth a combined $701M — up 19% from $587M a quarter earlier.

Buyers outnumbered sellers: 19 funds opened new KPTI positions and 8 closed out — a net gain of 11 holders — while 29 added to existing stakes and 19 trimmed.

The largest buyer was Fidelity Investments, adding an estimated $32M. The largest seller was PFM Health Sciences, cutting an estimated $10.4M.

  • 81 institutional investors held Karyopharm Therapeutics (KPTI) as of Q4 2014, up from 71 in Q3 2014.
  • Funds reported $701M of Karyopharm Therapeutics stock for Q4 2014, up 19% quarter-over-quarter.
  • 19 funds opened new Karyopharm Therapeutics positions in Q4 2014 and 8 closed out, a net change of +11 holders.
  • The largest Karyopharm Therapeutics buyer in Q4 2014 was Fidelity Investments, an estimated $32M added.
  • The largest Karyopharm Therapeutics seller in Q4 2014 was PFM Health Sciences, an estimated $10.4M sold.

Based on aggregated 13F filings for Q4 2014.