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Spyre Therapeutics

55 hedge funds and large institutions have $22.6M invested in Spyre Therapeutics in 2022 Q3 according to their latest regulatory filings, with 4 funds opening new positions, 11 increasing their positions, 14 reducing their positions, and 15 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
55
Holders Change
-11
Holders Change %
-16.67%
% of All Funds
0.95%
Holding in Top 10
1
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
0.02%
New
4
Increased
11
Reduced
14
Closed
15
Calls
$8K
Puts
Net Calls
+$8K
Net Calls Change
-$15K
Name Holding Trade Value Shares
Change
Shares
Change %
YF
26
Yu Fan
$59K
FSA
27
Franklin Street Advisors
North Carolina
$56K
Two Sigma Investments
28
Two Sigma Investments
New York
$54K -$111K -8,490 -67%
William Blair & Company
29
William Blair & Company
Illinois
$40K
RWM
30
Ritholtz Wealth Management
New York
$40K
Northern Trust
31
Northern Trust
Illinois
$36K
Citadel Advisors
32
Citadel Advisors
Florida
$32K -$87.6K -6,657 -73%
IA
33
IFP Advisors
Florida
$29K
Qube Research & Technologies (QRT)
34
Qube Research & Technologies (QRT)
United Kingdom
$19K -$2.33K -179 -11%
Man Group
35
Man Group
United Kingdom
$18K +$18K +1,379 New
Franklin Resources
36
Franklin Resources
California
$16K
TSS
37
Two Sigma Securities
New York
$16K +$16K +1,242 New
TRCT
38
Tower Research Capital (TRC)
New York
$14K +$5.82K +447 +71%
BC
39
BIT Capital
Germany
$13.2K
Bank of New York Mellon
40
Bank of New York Mellon
New York
$12K -$982 -76 -8%
LP
41
LMR Partners
United Kingdom
$10K
Bank of America
42
Bank of America
North Carolina
$6K +$2.25K +175 +60%
Simplex Trading
43
Simplex Trading
Illinois
$6K +$5.99K +524 +52,400%
RCM
44
RA Capital Management
Massachusetts
$5K +$5K +418 New
Group One Trading
45
Group One Trading
Illinois
$2K
JPMorgan Chase & Co
46
JPMorgan Chase & Co
New York
$2K +$726 +53 +57%
Federated Hermes
47
Federated Hermes
Pennsylvania
$1K
Wells Fargo
48
Wells Fargo
California
$1K +$30 +3 +3%
Royal Bank of Canada
49
Royal Bank of Canada
Ontario, Canada
$1K +$518 +29 +107%
O
50
OrbiMed
New York
$945